Regulating Apoptosis by Degradation: The N-End Rule-Mediated Regulation of Apoptotic Proteolytic Fragments in Mammalian Cells
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Regulating Apoptosis by Degradation: The N-End Rule-Mediated Regulation of Apoptotic Proteolytic Fragments in Mammalian Cells
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 11, Pages 3414
Publisher
MDPI AG
Online
2018-10-31
DOI
10.3390/ijms19113414
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Emerging branches of the N-end rule pathways are revealing the sequence complexities of N-termini dependent protein degradation
- (2018) Mohamed A. Eldeeb et al. Biochemistry and Cell Biology
- Novel roles of apoptotic caspases in tumor repopulation, epigenetic reprogramming, carcinogenesis, and beyond
- (2018) Ruya Zhao et al. CANCER AND METASTASIS REVIEWS
- Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells
- (2018) Min Zhou et al. INTERNATIONAL JOURNAL OF CANCER
- Apoptosis Reversal Promotes Cancer Stem Cell-Like Cell Formation
- (2018) Yiyue Xu et al. NEOPLASIA
- Post-translational N-terminal Arginylation of Protein Fragments: A Pivotal Portal to Proteolysis.
- (2018) Mohamed A. Eldeeb et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- A molecular signature for anastasis, recovery from the brink of apoptotic cell death
- (2017) Gongping Sun et al. JOURNAL OF CELL BIOLOGY
- Life and death of proteins after protease cleavage: protein degradation by the N-end rule pathway
- (2017) Nico Dissmeyer et al. NEW PHYTOLOGIST
- An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes
- (2017) Shun-Jia Chen et al. SCIENCE
- A picorna-like virus suppresses the N-end rule pathway to inhibit apoptosis
- (2017) Zhaowei Wang et al. eLife
- Phosphorylation Impacts N-end Rule Degradation of the Proteolytically Activated Form of BMX Kinase
- (2016) Mohamed A. Eldeeb et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The-N-End Rule: The Beginning Determines the End
- (2016) Mohamed Eldeeb et al. PROTEIN AND PEPTIDE LETTERS
- Posttranslational arginylation enzyme Ate1 affects DNA mutagenesis by regulating stress response
- (2016) Akhilesh Kumar et al. Cell Death & Disease
- Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers
- (2015) R Rai et al. ONCOGENE
- Cell Death Signaling
- (2015) Douglas R. Green et al. Cold Spring Harbor Perspectives in Biology
- In vivo CaspaseTracker biosensor system for detecting anastasis and non-apoptotic caspase activity
- (2015) Ho Lam Tang et al. Scientific Reports
- The anti-apoptotic form of tyrosine kinase Lyn that is generated by proteolysis is degraded by the N-end rule pathway
- (2015) Mohamed A. Eldeeb et al. Oncotarget
- Mutation of a Self-Processing Site in Caspase-8 Compromises Its Apoptotic but Not Its Nonapoptotic Functions in Bacterial Artificial Chromosome-Transgenic Mice
- (2014) T.-B. Kang et al. JOURNAL OF IMMUNOLOGY
- The N-Terminal Methionine of Cellular Proteins as a Degradation Signal
- (2013) Heon-Ki Kim et al. CELL
- Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway
- (2013) Anna Shemorry et al. MOLECULAR CELL
- Caspase Functions in Cell Death and Disease
- (2013) D. R. McIlwain et al. Cold Spring Harbor Perspectives in Biology
- Cellular Mechanisms Controlling Caspase Activation and Function
- (2013) A. B. Parrish et al. Cold Spring Harbor Perspectives in Biology
- The Ubiquitin System, an Immense Realm
- (2012) Alexander Varshavsky Annual Review of Biochemistry
- Regulation of Pluripotency and Cellular Reprogramming by the Ubiquitin-Proteasome System
- (2012) Shannon M. Buckley et al. Cell Stem Cell
- The C-terminal Proteolytic Fragment of the Breast Cancer Susceptibility Type 1 Protein (BRCA1) Is Degraded by the N-end Rule Pathway
- (2012) Zhizhong Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The DegraBase: A Database of Proteolysis in Healthy and Apoptotic Human Cells
- (2012) Emily D. Crawford et al. MOLECULAR & CELLULAR PROTEOMICS
- Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic response
- (2012) Ho Lam Tang et al. MOLECULAR BIOLOGY OF THE CELL
- The Auto-Generated Fragment of the Usp1 Deubiquitylase Is a Physiological Substrate of the N-End Rule Pathway
- (2012) Konstantin I. Piatkov et al. MOLECULAR CELL
- Quantitative profiling of caspase-cleaved substrates reveals different drug-induced and cell-type patterns in apoptosis
- (2012) K. Shimbo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments
- (2012) K. I. Piatkov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Granzyme B in injury, inflammation, and repair
- (2012) Paul R. Hiebert et al. TRENDS IN MOLECULAR MEDICINE
- Tyrosine kinase Etk/BMX protects nasopharyngeal carcinoma cells from apoptosis induced by radiation
- (2011) Zhenhua Zhang et al. CANCER BIOLOGY & THERAPY
- Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants
- (2011) Daniel J. Gibbs et al. NATURE
- The N-end rule pathway and regulation by proteolysis
- (2011) Alexander Varshavsky PROTEIN SCIENCE
- Activation of Specific Apoptotic Caspases with an Engineered Small-Molecule-Activated Protease
- (2010) Daniel C. Gray et al. CELL
- Apoptotic Caspases Regulate Induction of iPSCs from Human Fibroblasts
- (2010) Fang Li et al. Cell Stem Cell
- Gradients of a Ubiquitin E3 Ligase Inhibitor and a Caspase Inhibitor Determine Differentiation or Death in Spermatids
- (2010) Yosef Kaplan et al. DEVELOPMENTAL CELL
- Mutational effects and the evolution of new protein functions
- (2010) Misha Soskine et al. NATURE REVIEWS GENETICS
- Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases
- (2010) Woo Suk Choi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis of substrate recognition and specificity in the N-end rule pathway
- (2010) Edna Matta-Camacho et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The molecular principles of N-end rule recognition
- (2010) Shashikanth M Sriram et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals
- (2010) C.-S. Hwang et al. SCIENCE
- Caspase-mediated protein kinase C-δ cleavage is necessary for apoptosis of vascular smooth muscle cells
- (2009) Kaori Kato et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS
- (2009) Verena J Schuenemann et al. EMBO REPORTS
- Life and death by death receptors
- (2009) Maria Eugenia Guicciardi et al. FASEB JOURNAL
- Human Caspases: Activation, Specificity, and Regulation
- (2009) Cristina Pop et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells
- (2009) P Gamas et al. LEUKEMIA
- Cell Death
- (2009) Richard S. Hotchkiss et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molecular basis of substrate selection by the N-end rule adaptor protein ClpS
- (2009) G. Roman-Hernandez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP21
- (2008) John W. Blankenship et al. BIOCHEMICAL JOURNAL
- Reversibility of apoptosis in cancer cells
- (2008) H L Tang et al. BRITISH JOURNAL OF CANCER
- Killing of macrophages by anthrax lethal toxin: involvement of the N-end rule pathway
- (2008) Katherine E. Wickliffe et al. CELLULAR MICROBIOLOGY
- Regulation of apoptosis by XIAP ubiquitin-ligase activity
- (2008) A. J. Schile et al. GENES & DEVELOPMENT
- Senescence, Apoptosis or Autophagy?
- (2008) José Miguel Vicencio et al. GERONTOLOGY
- The Substrate Recognition Domains of the N-end Rule Pathway
- (2008) Takafumi Tasaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrate-binding Sites of UBR1, the Ubiquitin Ligase of the N-end Rule Pathway
- (2008) Zanxian Xia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis
- (2008) Mads Gyrd-Hansen et al. NATURE CELL BIOLOGY
- Apoptosis: controlled demolition at the cellular level
- (2007) Rebecca C. Taylor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started