Elevated Levels of Selenium Species in Cerebrospinal Fluid of Amyotrophic Lateral Sclerosis Patients with Disease-Associated Gene Mutations

OldversusNew Mechanisms in the Pathogenesis of ALS

(2016) Simona Rossi et al.   BRAIN PATHOLOGY

New ALS-Related Genes Expand theSpectrum Paradigmof Amyotrophic Lateral Sclerosis

(2016) Mario Sabatelli et al.   BRAIN PATHOLOGY

Long-term mortality patterns in a residential cohort exposed to inorganic selenium in drinking water

(2016) Marco Vinceti et al.   ENVIRONMENTAL RESEARCH

Reduced levels of alpha-1-antitrypsin in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a novel approach for a potential treatment

(2016) Uri Wormser et al.   Journal of Neuroinflammation

High Dietary Selenium Intake Alters Lipid Metabolism and Protein Synthesis in Liver and Muscle of Pigs

(2016) Zeping Zhao et al.   JOURNAL OF NUTRITION

Distribution of selenium in zebrafish larvae after exposure to organic and inorganic selenium forms

(2016) N. V. Dolgova et al.   Metallomics

Differing cytotoxicity and bioavailability of selenite, methylselenocysteine, selenomethionine, selenosugar 1 and trimethylselenonium ion and their underlying metabolic transformations in human cells

(2016) Talke Anu Marschall et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Decoding ALS: from genes to mechanism

(2016) J. Paul Taylor et al.   NATURE

ALS: A bucket of genes, environment, metabolism and unknown ingredients

(2016) Mónica Zufiría et al.   PROGRESS IN NEUROBIOLOGY

Selenite induces DNA damage and specific mitochondrial degeneration in human bladder cancer cells

(2016) K. Řezáčová et al.   TOXICOLOGY IN VITRO

Embryo Microinjection of Selenomethionine Reduces Hatchability and Modifies Oxidant Responsive Gene Expression in Zebrafish

(2016) J. K. Thomas et al.   Scientific Reports

Association of Environmental Toxins With Amyotrophic Lateral Sclerosis

(2016) Feng-Chiao Su et al.   JAMA Neurology

Antioxidant Rescue of Selenomethionine-Induced Teratogenesis in Zebrafish Embryos

(2015) M. C. Arnold et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Trans-sulfuration Pathway Seleno-amino Acids Are Mediators of Selenomethionine Toxicity inSaccharomyces cerevisiae*

(2015) Myriam Lazard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging mechanisms of molecular pathology in ALS

(2015) Owen M. Peters et al.   JOURNAL OF CLINICAL INVESTIGATION

Selenium and Human Health: Witnessing a Copernican Revolution?

(2015) Ewa Jablonska et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

TUBA4A gene analysis in sporadic amyotrophic lateral sclerosis: identification of novel mutations

(2015) Viviana Pensato et al.   JOURNAL OF NEUROLOGY

Selenite-Induced Toxicity in Cancer Cells Is Mediated by Metabolic Generation of Endogenous Selenium Nanoparticles

(2015) Peng Bao et al.   JOURNAL OF PROTEOME RESEARCH

Selenium speciation in human serum and its implications for epidemiologic research: a cross-sectional study

(2015) Marco Vinceti et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Amyotrophic lateral sclerosis: mechanisms and therapeutics in the epigenomic era

(2015) Ximena Paez-Colasante et al.   Nature Reviews Neurology

Risk factors for amyotrophic lateral sclerosis

(2015) Fang Fang et al.   Clinical Epidemiology

Serum thioredoxin reductase levels increase in response to chemically induced acute liver injury

(2014) Kang Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Direct Interaction between Selenoprotein P and Tubulin

(2014) Xiubo Du et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identical twins with the C9orf72 repeat expansion are discordant for ALS

(2014) Z. Xi et al.   NEUROLOGY

Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS

(2014) Bradley N. Smith et al.   NEURON

Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis

(2013) Emanuele D’Amico et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo

(2013) Kejian Shi et al.   Journal of Hematology & Oncology

The epidemiology of ALS: a conspiracy of genes, environment and time

(2013) Ammar Al-Chalabi et al.   Nature Reviews Neurology

Cerebrospinal fluid of newly diagnosed amyotrophic lateral sclerosis patients exhibits abnormal levels of selenium species including elevated selenite

(2013) Marco Vinceti et al.   NEUROTOXICOLOGY

Selenium neurotoxicity in humans: Bridging laboratory and epidemiologic studies

(2013) Marco Vinceti et al.   TOXICOLOGY LETTERS

Selenium speciation in paired serum and cerebrospinal fluid samples

(2012) Nikolay Solovyev et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia

(2012) Joshua Hersheson et al.   ANNALS OF NEUROLOGY

Metal Concentrations in Cerebrospinal Fluid and Blood Plasma from Patients with Amyotrophic Lateral Sclerosis

(2012) Per M. Roos et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

The need for a reassessment of the safe upper limit of selenium in drinking water

(2012) Marco Vinceti et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Serum selenium and single-nucleotide polymorphisms in genes for selenoproteins: relationship to markers of oxidative stress in men from Auckland, New Zealand

(2011) Nishi Karunasinghe et al.   Genes and Nutrition

Low levels of selenium compounds are selectively toxic for a human neuron cell line through ROS/RNS increase and apoptotic process activation

(2011) Tullia Maraldi et al.   NEUROTOXICOLOGY

Review on metal speciation analysis in cerebrospinal fluid—current methods and results: A review

(2010) Bernhard Michalke et al.   ANALYTICA CHIMICA ACTA

A prospective study of dietary selenium intake and risk of type 2 diabetes

(2010) Saverio Stranges et al.   BMC PUBLIC HEALTH

The relation between amyotrophic lateral sclerosis and inorganic selenium in drinking water: a population-based case-control study

(2010) Marco Vinceti et al.   Environmental Health

Contribution to selenium speciation in cerebrospinal fluid samples

(2010) Bernhard Michalke et al.   JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

Microtubule inhibitors: Differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistance

(2009) E. A. Perez   MOLECULAR CANCER THERAPEUTICS