mTOR regulates TLR-induced c-fos and Th1 responses to HBV and HCV vaccines

TSC1 controls macrophage polarization to prevent inflammatory disease

(2014) Linnan Zhu et al.   Nature Communications

Ever closer to a prophylactic vaccine for HCV

(2013) Leo Swadling et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Inhibition of Mechanistic Target of Rapamycin Promotes Dendritic Cell Activation and Enhances Therapeutic Autologous Vaccination in Mice

(2012) E. Amiel et al.   JOURNAL OF IMMUNOLOGY

The Role of Tuberous Sclerosis Complex 1 in Regulating Innate Immunity

(2012) H. Pan et al.   JOURNAL OF IMMUNOLOGY

Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin

(2012) Lihua Min et al.   NATURE CELL BIOLOGY

The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock

(2012) Ezra Aksoy et al.   NATURE IMMUNOLOGY

Improving vaccine delivery using novel adjuvant systems

(2011) Michael E. Pichichero   Human vaccines & immunotherapeutics

A Central Role for mTOR Kinase in Homeostatic Proliferation Induced CD8+ T Cell Memory and Tumor Immunity

(2011) Qingsheng Li et al.   IMMUNITY

Progress in the development of preventive and therapeutic vaccines for hepatitis C virus

(2011) Joseph Torresi et al.   JOURNAL OF HEPATOLOGY

Convergence of the Mammalian Target of Rapamycin Complex 1- and Glycogen Synthase Kinase 3- -Signaling Pathways Regulates the Innate Inflammatory Response

(2011) H. Wang et al.   JOURNAL OF IMMUNOLOGY

Hepatitis C virus soluble E2 in combination with QuilA and CpG ODN induces neutralizing antibodies in mice

(2011) Marloes A. Naarding et al.   VACCINE

A Versatile Role of Mammalian Target of Rapamycin in Human Dendritic Cell Function and Differentiation

(2010) M. Haidinger et al.   JOURNAL OF IMMUNOLOGY

The phosphoproteome of toll-like receptor-activated macrophages

(2010) Gabriele Weintz et al.   Molecular Systems Biology

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans

(2009) Lyudmila Lyakh et al.   IMMUNOLOGICAL REVIEWS

TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells

(2009) Frank Kaiser et al.   JOURNAL OF EXPERIMENTAL MEDICINE

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL

Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells

(2008) M. Ohtani et al.   BLOOD

Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells

(2008) Frank Schmitz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response

(2008) Thomas Weichhart et al.   IMMUNITY

Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines

(2008) Q. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of multispecific Th-1 type immune response against HCV in mice by protein immunization using CpG and Montanide ISA 720 as adjuvants

(2008) Qi Qiu et al.   VACCINE