Ever closer to a prophylactic vaccine for HCV

Meta-analysis: the impact of IL28B polymorphisms on rapid and sustained virological response in HCV-2 and -3 patients

(2012) J. Schreiber et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Successful Vaccination Induces Multifunctional Memory T-Cell Precursors Associated With Early Control of Hepatitis C Virus

(2012) Su–Hyung Park et al.   GASTROENTEROLOGY

New challenges in viral hepatitis

(2012) David Thomas et al.   GUT

New direct-acting antiviral agents for the treatment of hepatitis C virus infection and perspectives

(2012) Christoph Welsch et al.   GUT

Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response

(2012) Susanna Naggie et al.   HEPATOLOGY

Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8+ T Cell Phenotypes

(2012) Evan W. Newell et al.   IMMUNITY

Low perforin expression of early differentiated HCV-specific CD8+ T cells limits their hepatotoxic potential

(2012) Juandy Jo et al.   JOURNAL OF HEPATOLOGY

HIV gag-specific immune response mediated by double negative (CD3+CD4−CD8−) T cells in HIV-exposed seronegative individuals

(2012) Clara Restrepo et al.   JOURNAL OF MEDICAL VIROLOGY

Mixed Vector Immunization With Recombinant Adenovirus and MVA Can Improve Vaccine Efficacy While Decreasing Antivector Immunity

(2012) Arturo Reyes-Sandoval et al.   MOLECULAR THERAPY

Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

(2012) Dan H. Barouch et al.   NATURE

Vaccine Vectors Derived from a Large Collection of Simian Adenoviruses Induce Potent Cellular Immunity Across Multiple Species

(2012) S. Colloca et al.   Science Translational Medicine

Novel Adenovirus-Based Vaccines Induce Broad and Sustained T Cell Responses to HCV in Man

(2012) E. Barnes et al.   Science Translational Medicine

Innate immune responses in hepatitis C virus infection

(2012) Kui Li et al.   Seminars in Immunopathology

A deep profiler's guide to cytometry

(2012) Sean C. Bendall et al.   TRENDS IN IMMUNOLOGY

Sustained viral load reduction in treatment-naive HCV genotype 1 infected patients after therapeutic peptide vaccination

(2012) Christoph S. Klade et al.   VACCINE

Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection

(2011) K. Fitzmaurice et al.   GUT

Interferon lambdas: the next cytokine storm

(2011) C. Kelly et al.   GUT

T cell responses in hepatitis C: the good, the bad and the unconventional

(2011) Paul Klenerman et al.   GUT

Hepatitis E virus (HEV)-specific T-cell responses are associated with control of HEV infection

(2011) Pothakamuri Venkata Suneetha et al.   HEPATOLOGY

Insights into human CD8+ T-cell memory using the yellow fever and smallpox vaccines

(2011) Rafi Ahmed et al.   IMMUNOLOGY AND CELL BIOLOGY

Hepatitis C virus resistance to protease inhibitors

(2011) Philippe Halfon et al.   JOURNAL OF HEPATOLOGY

CD8+ T Effector Memory Cells Protect against Liver-Stage Malaria

(2011) A. Reyes-Sandoval et al.   JOURNAL OF IMMUNOLOGY

Immunization of Human Volunteers With Hepatitis C Virus Envelope Glycoproteins Elicits Antibodies That Cross-Neutralize Heterologous Virus Strains

(2011) Zania Stamataki et al.   JOURNAL OF INFECTIOUS DISEASES

Clearance of Genotype 1b Hepatitis C Virus in Chimpanzees in the Presence of Vaccine-Induced E1-Neutralizing Antibodies

(2011) Babs E. Verstrepen et al.   JOURNAL OF INFECTIOUS DISEASES

A human memory T cell subset with stem cell–like properties

(2011) Luca Gattinoni et al.   NATURE MEDICINE

Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines

(2011) L. Flatz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolving epidemiology of hepatitis C virus

(2010) D. Lavanchy   CLINICAL MICROBIOLOGY AND INFECTION

Prevention of cancer by prophylactic human papillomavirus vaccines

(2010) Kihyuck Kwak et al.   CURRENT OPINION IN IMMUNOLOGY

Meta-Analysis of Hepatitis C Virus Vaccine Efficacy in Chimpanzees Indicates an Importance for Structural Proteins

(2010) Harel Dahari et al.   GASTROENTEROLOGY

Spontaneous Control of HCV Is Associated With Expression of HLA-B*57 and Preservation of Targeted Epitopes

(2010) Arthur Y. Kim et al.   GASTROENTEROLOGY

Natural killer cells and hepatitis C: action and reaction

(2010) K. Cheent et al.   GUT

Priming of CD4+ and CD8+ T cell responses using a HCV core ISCOMATRIX™ vaccine: A phase I study in healthy volunteers

(2010) Debbie Drane et al.   Human vaccines & immunotherapeutics

From Vaccines to Memory and Back

(2010) Federica Sallusto et al.   IMMUNITY

Living in a house of cards: re-evaluating CD8+ T-cell immune correlates against HIV

(2010) George Makedonas et al.   IMMUNOLOGICAL REVIEWS

Prospects for prophylactic and therapeutic vaccines against the hepatitis C viruses

(2010) Michael Houghton   IMMUNOLOGICAL REVIEWS

Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission

(2010) C. L. Brimacombe et al.   JOURNAL OF VIROLOGY

Immunogenicity and safety of different injection routes and schedules of IC41, a Hepatitis C virus (HCV) peptide vaccine

(2010) Christa Firbas et al.   VACCINE

Immune responses against a liver-stage malaria antigen induced by simian adenoviral vector AdCh63 and MVA prime–boost immunisation in non-human primates

(2010) Stefania Capone et al.   VACCINE

Safety and immunogenicity of HCV E1E2 vaccine adjuvanted with MF59 administered to healthy adults

(2010) Sharon E. Frey et al.   VACCINE

Perforin and IL-2 Upregulation Define Qualitative Differences among Highly Functional Virus-Specific Human CD8+ T Cells

(2010) George Makedonas et al.   PLoS Pathogens

DNA vaccine therapy for chronic hepatitis C virus (HCV) infection: immune control of a moving target

(2009) Matti Sällberg et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Spontaneous Control of Primary Hepatitis C Virus Infection and Immunity Against Persistent Reinfection

(2009) William O. Osburn et al.   GASTROENTEROLOGY

Characterization of the cellular immune response in hepatitis C virus infection

(2009) Xinjian Zhang et al.   MEDICINAL RESEARCH REVIEWS

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

(2009) Luca Gattinoni et al.   NATURE MEDICINE

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

(2009) Scott G Hansen et al.   NATURE MEDICINE

Immune responses during acute and chronic infection with hepatitis C virus

(2008) Shigeaki Ishii et al.   CLINICAL IMMUNOLOGY

Phenotype and function of human T lymphocyte subsets: Consensus and issues

(2008) Victor Appay et al.   CYTOMETRY PART A

Therapeutic Vaccination of Chronic Hepatitis C Nonresponder Patients With the Peptide Vaccine IC41

(2008) Christoph S. Klade et al.   GASTROENTEROLOGY

Immunogenicity of CIGB-230, a therapeutic DNA vaccine preparation, in HCV-chronically infected individuals in a Phase I clinical trial

(2008) L. Alvarez-Lajonchere et al.   JOURNAL OF VIRAL HEPATITIS

Genetic History of Hepatitis C Virus in East Asia

(2008) O. G. Pybus et al.   JOURNAL OF VIROLOGY

Evidence for Protection against Chronic Hepatitis C Virus Infection in Chimpanzees by Immunization with Replicating Recombinant Vaccinia Virus

(2008) J.-W. Youn et al.   JOURNAL OF VIROLOGY

Induction of Broad CD4+ and CD8+ T-Cell Responses and Cross- Neutralizing Antibodies against Hepatitis C Virus by Vaccination with Th1-Adjuvanted Polypeptides Followed by Defective Alphaviral Particles Expressing Envelope Glycoproteins gpE1 and gpE2 and Nonstructural Proteins 3, 4, and 5

(2008) Y. Lin et al.   JOURNAL OF VIROLOGY

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Potential impact of vaccination on the hepatitis C virus epidemic in injection drug users

(2008) Judith A. Hahn et al.   Epidemics

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY