Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The role of JNK in the development of hepatocellular carcinoma

(2011) Madhumita Das et al.   GENES & DEVELOPMENT

Prevention of recurrence after resection of hepatocellular carcinoma: A daunting challenge

(2011) Ronnie T.P. Poon   HEPATOLOGY

Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation

(2010) Guobin He et al.   CANCER CELL

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis

(2010) Hyun-Seok Kim et al.   Cell Metabolism

Selective activation of p53-mediated tumour suppression in high-grade tumours

(2010) Melissa R. Junttila et al.   NATURE

Stage-specific sensitivity to p53 restoration during lung cancer progression

(2010) David M. Feldser et al.   NATURE

Mouse Models of Hepatocellular Carcinoma

(2010) Nelson Fausto et al.   SEMINARS IN LIVER DISEASE

Cancer prevention: major initiatives and looking into the future

(2010) Carolyn Cook Gotay   Expert Review of Pharmacoeconomics & Outcomes Research

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

Histological patterns in drug-induced liver disease

(2009) R Ramachandran et al.   JOURNAL OF CLINICAL PATHOLOGY

A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine

(2008) Karen R Reed et al.   BMC CANCER

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

(2008) Lijian Hui et al.   JOURNAL OF CLINICAL INVESTIGATION

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis

(2008) Rui-Hong Wang et al.   MOLECULAR CELL

Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia

(2008) Aline Bozec et al.   NATURE

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

(2008) Eriko Michishita et al.   NATURE