Role of circular RNAs in cardiovascular diseases

CaMKII-mediated phosphorylation of RyR2 plays a crucial role in aberrant Ca 2+ release as an arrhythmogenic substrate in cardiac troponin T-related familial hypertrophic cardiomyopathy

(2018) Shinichi Okuda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A potential risk factor of essential hypertension in case-control study: Circular RNA hsa_circ_0037911

(2018) Xingjie Bao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Abnormalities of Mitochondrial Dynamics in the Failing Heart: Normalization Following Long-Term Therapy with Elamipretide

(2018) Hani N. Sabbah et al.   CARDIOVASCULAR DRUGS AND THERAPY

An Evaluation of Function of Multicopy Noncoding RNAs in Mammals Using ENCODE/FANTOM Data and Comparative Genomics

(2018) Marc P Hoeppner et al.   MOLECULAR BIOLOGY AND EVOLUTION

Circular RNAs in heart failure

(2017) Yvan Devaux et al.   EUROPEAN JOURNAL OF HEART FAILURE

Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease

(2017) D. Siede et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Phenotype and Clinical Outcomes of Titin Cardiomyopathy

(2017) Upasana Tayal et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

(2017) Yibing Yang et al.   JNCI-Journal of the National Cancer Institute

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

(2017) Ivano Legnini et al.   MOLECULAR CELL

RNA targeting with CRISPR–Cas13

(2017) Omar O. Abudayyeh et al.   NATURE

Role of titin in cardiomyopathy: from DNA variants to patient stratification

(2017) James S. Ware et al.   Nature Reviews Cardiology

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

(2017) Monika Piwecka et al.   SCIENCE

Peripheral blood circular RNA hsa_circ_0124644 can be used as a diagnostic biomarker of coronary artery disease

(2017) Zhenzhou Zhao et al.   Scientific Reports

A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair

(2017) Yan Zeng et al.   Theranostics

Circular RNAs in Cardiovascular Disease: An Overview

(2017) Ximin Fan et al.   Biomed Research International

Carotid Plaque Rupture Is Accompanied by an Increase in the Ratio of Serum circR-284 to miR-221 LevelsCLINICAL PERSPECTIVE

(2017) Hernan A. Bazan et al.   Circulation-Cardiovascular Genetics

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

(2017) Yibing Yang et al.   JNCI-Journal of the National Cancer Institute

RBM20 Regulates Circular RNA Production From the Titin Gene

(2016) Mohsin A Khan et al.   CIRCULATION RESEARCH

A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223

(2016) Kun Wang et al.   EUROPEAN HEART JOURNAL

Characterization of circular RNAs in human, mouse and rat hearts

(2016) Stanislas Werfel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans

(2016) Lesca M. Holdt et al.   Nature Communications

Functions of long noncoding RNAs in the nucleus

(2016) Bin Yu et al.   Nucleus

Functions of long noncoding RNAs in the nucleus

(2016) Bin Yu et al.   Nucleus

Profiling and Validation of the Circular RNA Repertoire in Adult Murine Hearts

(2016) Tobias Jakobi et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

The Circular RNA Cdr1as Promotes Myocardial Infarction by Mediating the Regulation of miR-7a on Its Target Genes Expression

(2016) Hai-Hua Geng et al.   PLoS One

Specific identification and quantification of circular RNAs from sequencing data

(2015) Jun Cheng et al.   BIOINFORMATICS

Circular RNA: A new star of noncoding RNAs

(2015) Shibin Qu et al.   CANCER LETTERS

The RNA Binding Protein Quaking Regulates Formation of circRNAs

(2015) Simon J. Conn et al.   CELL

MicroRNA-155 Exerts Cell-Specific Antiangiogenic but Proarteriogenic Effects During Adaptive NeovascularizationCLINICAL PERSPECTIVE

(2015) Franziska Pankratz et al.   CIRCULATION

Transformative Impact of Proteomics on Cardiovascular Health and Disease

(2015) Merry L. Lindsey et al.   CIRCULATION

The Expression ofNPPASplice Variants During Mouse Cardiac Development

(2015) Masoumeh Fakhr Taha et al.   DNA AND CELL BIOLOGY

Circular RNA and Splicing: Skip Happens

(2015) Jeffrey Wilusz   JOURNAL OF MOLECULAR BIOLOGY

Pleiotropic effects of statins in hypercholesterolaemia: a prospective observational study using a lipoproteomic based approach

(2015) Sanjay Bhandari et al.   LANCET

Cyclic RNA has-circ-000595 regulates apoptosis of aortic smooth muscle cells

(2015) CHENGFEI ZHENG et al.   Molecular Medicine Reports

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor

(2015) Yehoshua Enuka et al.   NUCLEIC ACIDS RESEARCH

Circular RNA participates in the carcinogenesis and the malignant behavior of cancer

(2015) Zhen-Jun Zhao et al.   RNA Biology

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway

(2015) Fang Li et al.   Oncotarget

Rolling Circle Translation of Circular RNA in Living Human Cells

(2015) Naoko Abe et al.   Scientific Reports

Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals

(2015) Andranik Ivanov et al.   Cell Reports

Identification and Characterization of Circular RNAs As a New Class of Putative Biomarkers in Human Blood

(2015) Sebastian Memczak et al.   PLoS One

Biogenesis of Circular RNAs

(2014) Quentin Vicens et al.   CELL

LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis, and Atherosclerosis by Enhancing p53 Activity

(2014) Gengze Wu et al.   CIRCULATION

Circulating Long Noncoding RNA, LIPCAR, Predicts Survival in Patients With Heart Failure

(2014) Regalla Kumarswamy et al.   CIRCULATION RESEARCH

The Landscape of MicroRNA, Piwi-Interacting RNA, and Circular RNA in Human Saliva

(2014) J. H. Bahn et al.   CLINICAL CHEMISTRY

Short intronic repeat sequences facilitate circular RNA production

(2014) Dongming Liang et al.   GENES & DEVELOPMENT

Novel Mutations Widen the Phenotypic Spectrum of Slow Skeletal/β-Cardiac Myosin (MYH7) Distal Myopathy

(2014) Phillipa J. Lamont et al.   HUMAN MUTATION

A long noncoding RNA protects the heart from pathological hypertrophy

(2014) Pei Han et al.   NATURE

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment

(2013) Carla A. Klattenhoff et al.   CELL

Cardiac Myocyte Z-Line Calmodulin Is Mainly RyR2-Bound, and Reduction Is Arrhythmogenic and Occurs in Heart Failure

(2013) Yi Yang et al.   CIRCULATION RESEARCH

Cardiomyocyte apoptosis in the failing heart — A critical review from definition and classification of cell death

(2013) Genzou Takemura et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Molecular Mechanisms Underlying Cardiac Protein Phosphatase 2A Regulation in Heart

(2012) Sean T. DeGrande et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Truncations of Titin Causing Dilated Cardiomyopathy

(2012) Daniel S. Herman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction

(2011) Christopher J. O'Donnell et al.   CIRCULATION

The Concept of Metabolic Syndrome: Contribution of Visceral Fat Accumulation and Its Molecular Mechanism

(2011) Yuji Matsuzawa et al.   Journal of Atherosclerosis and Thrombosis

Regulation of Human Cardiac Ion Channel Genes by MicroRNAs: Theoretical Perspective and Pathophysiological Implications

(2010) Xiaobin Luo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk

(2010) Christin E. Burd et al.   PLoS Genetics

Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus

(2009) Olga Jarinova et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

The search for new cardiovascular biomarkers

(2008) Robert E. Gerszten et al.   NATURE