Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 5, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-04-02
DOI
10.3389/fonc.2015.00069
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Glutaminase: A Hot Spot For Regulation Of Cancer Cell Metabolism?
- (2015) Oncotarget
- The eIF4E/eIF4G Interaction Inhibitor 4EGI-1 Augments TRAIL-Mediated Apoptosis through c-FLIP Down-regulation and DR5 Induction Independent of Inhibition of Cap-Dependent Protein Translation
- (2015) Songqing Fan et al. NEOPLASIA
- Enhancement of tumor-TRAIL susceptibility by modulation of autophagy
- (2014) Wen Hou et al. Autophagy
- The novel thymidylate synthase inhibitor trifluorothymidine (TFT) and TRAIL synergistically eradicate non-small cell lung cancer cells
- (2014) Kaamar Azijli et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- DAPK2 is a novel modulator of TRAIL-induced apoptosis
- (2014) C R Schlegel et al. CELL DEATH AND DIFFERENTIATION
- Getting TRAIL back on track for cancer therapy
- (2014) J Lemke et al. CELL DEATH AND DIFFERENTIATION
- Inhibition of Yin Yang 1-Dependent Repressor Activity of DR5 Transcription and Expression by the Novel Proteasome Inhibitor NPI-0052 Contributes to its TRAIL-Enhanced Apoptosis in Cancer Cells
- (2014) Stavroula Baritaki et al. JOURNAL OF IMMUNOLOGY
- Bortezomib Sensitizes Primary Meningioma Cells to TRAIL-Induced Apoptosis by Enhancing Formation of the Death-Inducing Signaling Complex
- (2014) Ronald Koschny et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Gold(III)-Dithiocarbamato Peptidomimetics in the Forefront of the Targeted Anticancer Therapy: Preclinical Studies against Human Breast Neoplasia
- (2014) Chiara Nardon et al. PLoS One
- Trail Resistance Induces Epithelial-Mesenchymal Transition and Enhances Invasiveness by Suppressing PTEN via miR-221 in Breast Cancer
- (2014) Haiji Wang et al. PLoS One
- Bortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism
- (2014) J Bullenkamp et al. Cell Death & Disease
- DRUGSURV: a resource for repositioning of approved and experimental drugs in oncology based on patient survival information
- (2014) I Amelio et al. Cell Death & Disease
- Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma
- (2014) G Grazia et al. Cell Death & Disease
- Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway
- (2014) R Trivedi et al. Cell Death & Disease
- Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells
- (2014) Y Teng et al. Cell Death & Disease
- TRAIL and proteasome inhibitors combination induces a robust apoptosis in human malignant pleural mesothelioma cells through Mcl-1 and Akt protein cleavages
- (2013) Bao-Zhu Yuan et al. BMC CANCER
- A novel inhibitor of proteasome deubiquitinating activity renders tumor cells sensitive to TRAIL-mediated apoptosis by natural killer cells and T cells
- (2013) Dhifaf Sarhan et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Monensin, a polyether ionophore antibiotic, overcomes TRAIL resistance in glioma cells via endoplasmic reticulum stress, DR5 upregulation and c-FLIP downregulation
- (2013) Mi Jin Yoon et al. CARCINOGENESIS
- The dark side of TRAIL signaling
- (2013) S Fulda CELL DEATH AND DIFFERENTIATION
- Epithelial-mesenchymal plasticity in carcinoma metastasis
- (2013) J. H. Tsai et al. GENES & DEVELOPMENT
- Neobavaisoflavone sensitizes apoptosis via the inhibition of metastasis in TRAIL-resistant human glioma U373MG cells
- (2013) Young-Joo Kim et al. LIFE SCIENCES
- The HSP70 and Autophagy Inhibitor Pifithrin- Enhances the Antitumor Effects of TRAIL on Human Pancreatic Cancer
- (2013) H. Monma et al. MOLECULAR CANCER THERAPEUTICS
- Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis
- (2013) T He et al. ONCOGENE
- Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27
- (2013) G Mellier et al. Cell Death & Disease
- Targeting cellular metabolism to improve cancer therapeutics
- (2013) Y Zhao et al. Cell Death & Disease
- Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
- (2013) X Sui et al. Cell Death & Disease
- Amurensin G, a novel SIRT1 inhibitor, sensitizes TRAIL-resistant human leukemic K562 cells to TRAIL-induced apoptosis
- (2012) Hak-Bong Kim et al. BIOCHEMICAL PHARMACOLOGY
- Elevation of c-FLIP in Castrate-Resistant Prostate Cancer Antagonizes Therapeutic Response to Androgen Receptor-Targeted Therapy
- (2012) C. McCourt et al. CLINICAL CANCER RESEARCH
- The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells
- (2012) Eun-Sil Sung et al. EXPERIMENTAL CELL RESEARCH
- Links between metabolism and cancer
- (2012) C. V. Dang GENES & DEVELOPMENT
- Diallyl trisulfide sensitizes human melanoma cells to TRAIL-induced cell death by promoting endoplasmic reticulum-mediated apoptosis
- (2012) MAYUMI MURAI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Targeting the Glyoxalase Pathway Enhances TRAIL Efficacy in Cancer Cells by Downregulating the Expression of Antiapoptotic Molecules
- (2012) H. Taniguchi et al. MOLECULAR CANCER THERAPEUTICS
- A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death
- (2012) Laura S. Dickens et al. MOLECULAR CELL
- Verrucarin A sensitizes TRAIL-induced apoptosis via the upregulation of DR5 in an eIF2α/CHOP-dependent manner
- (2012) Dong-Oh Moon et al. TOXICOLOGY IN VITRO
- ER stress sensitizes cells to TRAIL through down-regulation of FLIP and Mcl-1 and PERK-dependent up-regulation of TRAIL-R2
- (2011) Rosa Martín-Pérez et al. APOPTOSIS
- p53-Independent up-regulation of a TRAIL receptor DR5 by proteasome inhibitors: A mechanism for proteasome inhibitor-enhanced TRAIL-induced apoptosis
- (2011) Dai-Wu Seol BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hsp90 inhibitors and drug resistance in cancer: The potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugs
- (2011) Xiangyi Lu et al. BIOCHEMICAL PHARMACOLOGY
- 5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells
- (2011) Jian-Feng Yang et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL
- (2011) Vitaliy O. Kaminskyy et al. CARCINOGENESIS
- Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions
- (2011) Sarit Kahana et al. CELLULAR SIGNALLING
- High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde
- (2011) Hak-Bong Kim et al. Molecular Cancer
- Bortezomib Sensitizes Malignant Human Glioma Cells to TRAIL, Mediated by Inhibition of the NF- B Signaling Pathway
- (2011) E. P. Jane et al. MOLECULAR CANCER THERAPEUTICS
- The Role of Autophagy in Cancer: Therapeutic Implications
- (2011) Z. J. Yang et al. MOLECULAR CANCER THERAPEUTICS
- Oligomycin A enhances apoptotic effect of TRAIL through CHOP-mediated death receptor 5 expression
- (2011) Long He et al. MOLECULAR CARCINOGENESIS
- Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy
- (2011) Ahmad R. Safa et al. Cancers
- ROS and CHOP Are Critical for Dibenzylideneacetone to Sensitize Tumor Cells to TRAIL through Induction of Death Receptors and Downregulation of Cell Survival Proteins
- (2010) Sahdeo Prasad et al. CANCER RESEARCH
- Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice
- (2010) Hua-shan Shi et al. CANCER SCIENCE
- c-FLIPL enhances anti-apoptotic Akt functions by modulation of Gsk3β activity
- (2010) C Quintavalle et al. CELL DEATH AND DIFFERENTIATION
- Phase I Dose-Escalation Study of Recombinant Human Apo2L/TRAIL, a Dual Proapoptotic Receptor Agonist, in Patients With Advanced Cancer
- (2010) Roy S. Herbst et al. JOURNAL OF CLINICAL ONCOLOGY
- Bortezomib Sensitizes Human Renal Cell Carcinomas to TRAIL Apoptosis through Increased Activation of Caspase-8 in the Death-Inducing Signaling Complex
- (2010) Alan D. Brooks et al. MOLECULAR CANCER RESEARCH
- Bortezomib Sensitizes Human Esophageal Squamous Cell Carcinoma Cells to TRAIL-Mediated Apoptosis via Activation of Both Extrinsic and Intrinsic Apoptosis Pathways
- (2010) N. Seki et al. MOLECULAR CANCER THERAPEUTICS
- MS-275 Sensitizes TRAIL-Resistant Breast Cancer Cells, Inhibits Angiogenesis and Metastasis, and Reverses Epithelial-Mesenchymal Transition In vivo
- (2010) R. K. Srivastava et al. MOLECULAR CANCER THERAPEUTICS
- Clues from cell metabolism
- (2010) William G. Kaelin et al. NATURE
- New insights into apoptosis signaling by Apo2L/TRAIL
- (2010) F Gonzalvez et al. ONCOGENE
- Role of Endoplasmic Reticulum Stress in α-TEA Mediated TRAIL/DR5 Death Receptor Dependent Apoptosis
- (2010) Richa Tiwary et al. PLoS One
- Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway
- (2010) A. A. Khutornenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRAIL-Induced Apoptosis
- (2009) Nadia Corazza et al. Annals of the New York Academy of Sciences
- Immunogenic cell death, DAMPs and anticancer therapeutics: An emerging amalgamation
- (2009) Abhishek D. Garg et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo
- (2009) Ramon C. Sun et al. BREAST CANCER RESEARCH AND TREATMENT
- The Tumor Suppressor Par-4 Activates an Extrinsic Pathway for Apoptosis
- (2009) Ravshan Burikhanov et al. CELL
- Mapatumumab, a Fully Human Agonistic Monoclonal Antibody That Targets TRAIL-R1, in Combination with Gemcitabine and Cisplatin: a Phase I Study
- (2009) C. H. Mom et al. CLINICAL CANCER RESEARCH
- TNF-related apoptosis-inducing ligand (TRAIL): A new path to anti-cancer therapies
- (2009) Peter A. Holoch et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Cellular FLICE-inhibitory protein (c-FLIP) signalling: A key regulator of receptor-mediated apoptosis in physiologic context and in cancer
- (2009) Marina Bagnoli et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL
- (2009) Dolly G. Aguilera et al. JOURNAL OF NEURO-ONCOLOGY
- 2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2
- (2009) Hao Liu et al. Molecular Cancer
- Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells
- (2009) Andrea Viale et al. NATURE
- Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
- (2009) Sabrina L. Spencer et al. NATURE
- Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation
- (2009) L A Pradelli et al. ONCOGENE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Antitumor Activity of Bortezomib Alone and in Combination with Trail in Human Acute Myeloid Leukemia
- (2008) Concetta Conticello et al. ACTA HAEMATOLOGICA
- A novel humanized anti-human death receptor 5 antibody CS-1008 induces apoptosis in tumor cells without toxicity in hepatocytes
- (2008) A. Yada et al. ANNALS OF ONCOLOGY
- Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling
- (2008) Pritish S. Pawar et al. BIOCHEMICAL JOURNAL
- The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer
- (2008) S. Spaderna et al. CANCER RESEARCH
- Targeting the Eukaryotic Translation Initiation Factor 4E for Cancer Therapy
- (2008) J. R. Graff et al. CANCER RESEARCH
- Targeting the extrinsic apoptosis pathway in cancer
- (2008) Avi Ashkenazi CYTOKINE & GROWTH FACTOR REVIEWS
- Ligand-Based Targeting of Apoptosis in Cancer: The Potential of Recombinant Human Apoptosis Ligand 2/Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (rhApo2L/TRAIL)
- (2008) Avi Ashkenazi et al. JOURNAL OF CLINICAL ONCOLOGY
- Expression of the ZEB1 (δEF1) transcription factor in human: additional insights
- (2008) Elaine M. Hurt et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- 15-deoxy-Δ12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription
- (2008) Rong-Ying Su et al. MOLECULAR CANCER THERAPEUTICS
- 2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition
- (2008) D. Zhong et al. MOLECULAR CANCER THERAPEUTICS
- Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region
- (2008) K. Kandasamy et al. MOLECULAR CANCER THERAPEUTICS
- Potent Systemic Anticancer Activity of Adenovirally Expressed EGFR-Selective TRAIL Fusion Protein
- (2008) Edwin Bremer et al. MOLECULAR THERAPY
- Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
- (2008) Inki Kim et al. NATURE REVIEWS DRUG DISCOVERY
- 17-AAG sensitized malignant glioma cells to death-receptor mediated apoptosis
- (2008) Markus David Siegelin et al. NEUROBIOLOGY OF DISEASE
- Epigenetics in Cancer
- (2008) Manel Esteller NEW ENGLAND JOURNAL OF MEDICINE
- Mechanisms of enhancement of TRAIL tumoricidal activity against human cancer cells of different origin by dipyridamole
- (2008) A E Goda et al. ONCOGENE
- The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway
- (2008) S Wang ONCOGENE
- Metastasis: a therapeutic target for cancer
- (2008) Patricia S Steeg et al. Nature clinical practice. Oncology
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now