- Home
- Publications
- Publication Search
- Publication Details
Title
PP2A: The Wolf in Sheep’s Clothing?
Authors
Keywords
-
Journal
Cancers
Volume 7, Issue 2, Pages 648-669
Publisher
MDPI AG
Online
2015-04-11
DOI
10.3390/cancers7020648
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro
- (2014) Giulia Marvaso et al. CANCER BIOLOGY & THERAPY
- p16 Protein Expression and Human Papillomavirus Status As Prognostic Biomarkers of Nonoropharyngeal Head and Neck Squamous Cell Carcinoma
- (2014) Christine H. Chung et al. JOURNAL OF CLINICAL ONCOLOGY
- PP2A inhibition overcomes acquired resistance to HER2 targeted therapy
- (2014) Martina SJ McDermott et al. Molecular Cancer
- PP2A Inhibition Is a Common Event in Colorectal Cancer and Its Restoration Using FTY720 Shows Promising Therapeutic Potential
- (2014) I. Cristobal et al. MOLECULAR CANCER THERAPEUTICS
- PP2A: The Achilles Heal in MDS with 5q Deletion
- (2014) David A. Sallman et al. Frontiers in Oncology
- Deregulation of the phosphatase, PP2A is a common event in breast cancer, predicting sensitivity to FTY720
- (2014) Shawn Baldacchino et al. EPMA Journal
- Ceramide in the prostate
- (2013) Paul Dent CANCER BIOLOGY & THERAPY
- Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
- (2013) Parthasarathy Seshacharyulu et al. CANCER LETTERS
- Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells
- (2013) A. Khanna et al. CANCER RESEARCH
- Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53
- (2013) François H.T. Duong et al. CARCINOGENESIS
- Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3
- (2013) Miguel Perez-Aso et al. FASEB JOURNAL
- Combination of FTY720 with cisplatin exhibits antagonistic effects in ovarian cancer cells: Role of autophagy
- (2013) NING ZHANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Down-regulation of Wild-type p53-induced Phosphatase 1 (Wip1) Plays a Critical Role in Regulating Several p53-dependent Functions in Premature Senescent Tumor Cells
- (2013) Elvira Crescenzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein phosphatase 2A: a target for anticancer therapy
- (2013) Danilo Perrotti et al. LANCET ONCOLOGY
- Extended survival and reduced risk of AML progression in erythroid-responsive lenalidomide-treated patients with lower-risk del(5q) MDS
- (2013) A F List et al. LEUKEMIA
- The regulatory roles of phosphatases in cancer
- (2013) J Stebbing et al. ONCOGENE
- FTY720 inhibits tumor growth and enhances the tumor-suppressive effect of topotecan in neuroblastoma by interfering with the sphingolipid signaling pathway
- (2013) Mei-Hong Li et al. PEDIATRIC BLOOD & CANCER
- PP2A-Mediated Anticancer Therapy
- (2013) Weibo Chen et al. Gastroenterology Research and Practice
- PI3K independent activation of mTORC1 as a target in lapatinib-resistant ERBB2+ breast cancer cells
- (2012) Anna-Maria Jegg et al. BREAST CANCER RESEARCH AND TREATMENT
- Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis
- (2012) Sahar A. Saddoughi et al. EMBO Molecular Medicine
- The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity
- (2012) Ward Sents et al. FEBS Journal
- PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates
- (2012) Alison Kurimchak et al. GENE
- CIP2A-mediated Akt activation plays a role in bortezomib-induced apoptosis in head and neck squamous cell carcinoma cells
- (2012) Yu-Chin Lin et al. ORAL ONCOLOGY
- PP2A inactivation is a crucial step in triggering apoptin-induced tumor-selective cell killing
- (2012) R Zimmerman et al. Cell Death & Disease
- Somatic Mutations of PPP2R1A in Ovarian and Uterine Carcinomas
- (2011) Ie-Ming Shih et al. AMERICAN JOURNAL OF PATHOLOGY
- PP2A targeting by viral proteins: A widespread biological strategy from DNA/RNA tumor viruses to HIV-1
- (2011) Julien Guergnon et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Norcantharidin induces melanoma cell apoptosis through activation of TR3 dependent pathway
- (2011) Shujing Liu et al. CANCER BIOLOGY & THERAPY
- PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway
- (2011) Wei Li et al. CANCER LETTERS
- Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia
- (2011) I. Cristobal et al. HAEMATOLOGICA
- Reactivating PP2A by FTY720 as a Novel therapy for AML with C-KIT tyrosine kinase domain mutation
- (2011) Yan Yang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas
- (2011) Melissa K McConechy et al. JOURNAL OF PATHOLOGY
- Comparison of fingolimod with interferon beta-1a in relapsing-remitting multiple sclerosis: a randomised extension of the TRANSFORMS study
- (2011) Bhupendra Khatri et al. LANCET NEUROLOGY
- Low expression of PP2A regulatory subunit B55α is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients
- (2011) P P Ruvolo et al. LEUKEMIA
- PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect
- (2011) I Cristóbal et al. LEUKEMIA
- Human Cancer-Associated Mutations in the A Subunit of Protein Phosphatase 2A Increase Lung Cancer Incidence in A Knock-In and Knockout Mice
- (2011) R. Ruediger et al. MOLECULAR AND CELLULAR BIOLOGY
- Integrated genomic analyses of ovarian carcinoma
- (2011) D. Bell et al. NATURE
- Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition
- (2011) B N Rexer et al. ONCOGENE
- ETS1 Mediates MEK1/2-Dependent Overexpression of Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) in Human Cancer Cells
- (2011) Anchit Khanna et al. PLoS One
- Evaluation of PPP2R2A as a prostate cancer susceptibility gene: a comprehensive germline and somatic study
- (2011) Yu Cheng et al. Cancer Genetics
- B55β-Associated PP2A Complex Controls PDK1-Directed Myc Signaling and Modulates Rapamycin Sensitivity in Colorectal Cancer
- (2010) Jing Tan et al. CANCER CELL
- Essential Requirement for PP2A Inhibition by the Oncogenic Receptor c-KIT Suggests PP2A Reactivation as a Strategy to Treat c-KIT+ Cancers
- (2010) K. G. Roberts et al. CANCER RESEARCH
- Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis
- (2010) Wei Li et al. CANCER SCIENCE
- Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres
- (2010) Y. Tanno et al. GENES & DEVELOPMENT
- Functions of B56-containing PP2As in major developmental and cancer signaling pathways
- (2010) Jing Yang et al. LIFE SCIENCES
- Cdk5 phosphorylates non-genotoxically overexpressed p53 following inhibition of PP2A to induce cell cycle arrest/apoptosis and inhibits tumor progression
- (2010) Amrendra K Ajay et al. Molecular Cancer
- Resistance to ErbB2 Tyrosine Kinase Inhibitors in Breast Cancer Is Mediated by Calcium-Dependent Activation of RelA
- (2010) W. Xia et al. MOLECULAR CANCER THERAPEUTICS
- X-Linked Inhibitor of Apoptosis Protein Inhibits Apoptosis in Inflammatory Breast Cancer Cells with Acquired Resistance to an ErbB1/2 Tyrosine Kinase Inhibitor
- (2010) K. M. Aird et al. MOLECULAR CANCER THERAPEUTICS
- Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
- (2010) Volker Brinkmann et al. NATURE REVIEWS DRUG DISCOVERY
- A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
- (2010) Ludwig Kappos et al. NEW ENGLAND JOURNAL OF MEDICINE
- Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis
- (2010) Jeffrey A. Cohen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL
- (2009) L. Liu et al. CANCER RESEARCH
- Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis
- (2009) Shun-ichi Wada et al. CANCER SCIENCE
- A PP2A Regulatory Subunit Regulates C. elegans Insulin/IGF-1 Signaling by Modulating AKT-1 Phosphorylation
- (2009) Srivatsan Padmanabhan et al. CELL
- Suppression of growth of highly-metastatic human breast cancer cells by norcantharidin and its mechanisms of action
- (2009) Yan Huang et al. CYTOTECHNOLOGY
- The effect of a PP2A inhibitor on the nuclear receptor corepressor pathway in glioma
- (2009) Jie Lu et al. JOURNAL OF NEUROSURGERY
- Oral fingolimod (FTY720) in multiple sclerosis: Two-year results of a phase II extension study
- (2009) P. O'Connor et al. NEUROLOGY
- A critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide
- (2009) S. Wei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms
- (2009) Jie Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tyrosine 302 in RACK1 Is Essential for Insulin-like Growth Factor-I-mediated Competitive Binding of PP2A and β1 Integrin and for Tumor Cell Proliferation and Migration
- (2008) Patrick A. Kiely et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation
- (2008) Yanhui Xu et al. MOLECULAR CELL
- PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail)
- (2008) Veerle Janssens et al. TRENDS IN BIOCHEMICAL SCIENCES
- Multiple pathways regulated by the tumor suppressor PP2A in transformation
- (2008) Jukka Westermarck et al. TRENDS IN MOLECULAR MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search