FTY720 inhibits tumor growth and enhances the tumor-suppressive effect of topotecan in neuroblastoma by interfering with the sphingolipid signaling pathway
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Title
FTY720 inhibits tumor growth and enhances the tumor-suppressive effect of topotecan in neuroblastoma by interfering with the sphingolipid signaling pathway
Authors
Keywords
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Journal
PEDIATRIC BLOOD & CANCER
Volume 60, Issue 9, Pages 1418-1423
Publisher
Wiley
Online
2013-05-24
DOI
10.1002/pbc.24564
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Related references
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- (2011) Julie R. Park et al. JOURNAL OF CLINICAL ONCOLOGY
- Ablation of Sphingosine Kinase-2 Inhibits Tumor Cell Proliferation and Migration
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- Survival and late effects in children with stage 4 neuroblastoma
- (2011) Thomas Perwein et al. PEDIATRIC BLOOD & CANCER
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- Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their function
- (2010) Joanna M. Woodcock et al. CELLULAR SIGNALLING
- FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells
- (2010) Francesca Tonelli et al. CELLULAR SIGNALLING
- FTY720 Shows Promising In vitro and In vivo Preclinical Activity by Downmodulating Cyclin D1 and Phospho-Akt in Mantle Cell Lymphoma
- (2010) Q. Liu et al. CLINICAL CANCER RESEARCH
- Sphingosine Interaction with Acidic Leucine-rich Nuclear Phosphoprotein-32A (ANP32A) Regulates PP2A Activity and Cyclooxygenase (COX)-2 Expression in Human Endothelial Cells
- (2010) Cheryl Habrukowich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice
- (2010) Tongsen Zheng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2
- (2010) K. J. French et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor
- (2009) Mei-Hong Li et al. CANCER LETTERS
- Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti-inflammatory phenotype
- (2009) Andreas Weigert et al. INTERNATIONAL JOURNAL OF CANCER
- S1P/S1P2 Signaling Induces Cyclooxygenase-2 Expression in Wilms Tumor
- (2009) Mei-Hong Li et al. JOURNAL OF UROLOGY
- FTY720 Induces Apoptosis in Hepatocellular Carcinoma Cells through Activation of Protein Kinase C Signaling
- (2008) J.-H. Hung et al. CANCER RESEARCH
- Central nervous system-directed effects of FTY720 (fingolimod)
- (2008) Veronique E. Miron et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Neuroblastoma: Biology, Prognosis, and Treatment
- (2008) Julie R. Park et al. PEDIATRIC CLINICS OF NORTH AMERICA
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