IL-33 drives the antitumor effects of dendritic cells via the induction of Tc9 cells

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity

(2017) Abdulraouf Ramadan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils

(2017) Valeria Lucarini et al.   OncoImmunology

Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic

(2016) Kinga Majchrzak et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung

(2016) Ismé M. de Kleer et al.   IMMUNITY

IL-33 inhibits the differentiation and immunosuppressive activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

(2016) Hui Xuan Lim et al.   IMMUNOLOGY AND CELL BIOLOGY

Exogenous IL-33 Restores Dendritic Cell Activation and Maturation in Established Cancer

(2016) Donye Dominguez et al.   JOURNAL OF IMMUNOLOGY

Intratumorally Establishing Type 2 Innate Lymphoid Cells Blocks Tumor Growth

(2016) Juyang Kim et al.   JOURNAL OF IMMUNOLOGY

Effector, Memory, and Dysfunctional CD8+T Cell Fates in the Antitumor Immune Response

(2016) John Reiser et al.   Journal of Immunology Research

The Dynamic Role of the IL-33/ST2 Axis in Chronic Viral-infections: Alarming and Adjuvanting the Immune Response

(2016) Vikram Mehraj et al.   EBioMedicine

CD8 T Cell–Independent Antitumor Response and Its Potential for Treatment of Malignant Gliomas

(2016) Katherine Murphy et al.   Cancers

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

(2015) Ajithkumar Vasanthakumar et al.   NATURE IMMUNOLOGY

Alarmin IL-33 Acts as an Immunoadjuvant to Enhance Antigen-Specific Tumor Immunity

(2014) Daniel O. Villarreal et al.   CANCER RESEARCH

Tumoral Expression of IL-33 Inhibits Tumor Growth and Modifies the Tumor Microenvironment through CD8+T and NK Cells

(2014) Xin Gao et al.   JOURNAL OF IMMUNOLOGY

The alarmin IL-33 promotes regulatory T-cell function in the intestine

(2014) Chris Schiering et al.   NATURE

Tumor-specific IL-9–producing CD8+Tc9 cells are superior effector than type-I cytotoxic Tc1 cells for adoptive immunotherapy of cancers

(2014) Yong Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy

(2014) Yong Lu et al.   OncoImmunology

Transgenic expression of IL-33 activates CD8+ T cells and NK cells and inhibits tumor growth and metastasis in mice

(2013) Kun Gao et al.   CANCER LETTERS

Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy

(2013) Wei Liao et al.   IMMUNITY

Adoptive Transfer of Tc1 or Tc17 Cells Elicits Antitumor Immunity against Established Melanoma through Distinct Mechanisms

(2013) Y. Yu et al.   JOURNAL OF IMMUNOLOGY

OX40 signaling favors the induction of TH9 cells and airway inflammation

(2012) Xiang Xiao et al.   NATURE IMMUNOLOGY

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses

(2012) W. V. Bonilla et al.   SCIENCE

Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease

(2010) Xuebin Liu et al.   NATURE MEDICINE

Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation

(2010) Bertram Bengsch et al.   PLoS Pathogens

Regulating functional cell fates in CD8 T cells

(2009) Protul A. Shrikant et al.   IMMUNOLOGIC RESEARCH

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

Migration of Dendritic Cell Subsets and their Precursors

(2007) Gwendalyn J. Randolph et al.   Annual Review of Immunology