IL-33 inhibits the differentiation and immunosuppressive activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

Exogenous interleukin-33 targets myeloid-derived suppressor cells and generates periphery-induced Foxp3+regulatory T cells in skin-transplanted mice

(2015) Tania Gajardo et al.   IMMUNOLOGY

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

(2015) Ajithkumar Vasanthakumar et al.   NATURE IMMUNOLOGY

Interleukin 33 in tumor microenvironment is crucial for the accumulation and function of myeloid-derived suppressor cells

(2015) Peng Xiao et al.   OncoImmunology

Tumor-Derived Osteopontin Suppresses Antitumor Immunity by Promoting Extramedullary Myelopoiesis

(2014) E.-K. Kim et al.   CANCER RESEARCH

IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes

(2014) N. E. Humphreys et al.   JOURNAL OF IMMUNOLOGY

IL-33 Induces Antigen-Specific IL-5+ T Cells and Promotes Allergic-Induced Airway Inflammation Independent of IL-4

(2014) M. Kurowska-Stolarska et al.   JOURNAL OF IMMUNOLOGY

Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

(2014) J.-I. Youn et al.   JOURNAL OF IMMUNOLOGY

Tumoral Expression of IL-33 Inhibits Tumor Growth and Modifies the Tumor Microenvironment through CD8+T and NK Cells

(2014) Xin Gao et al.   JOURNAL OF IMMUNOLOGY

IL-33–Induced Hematopoietic Stem and Progenitor Cell Mobilization Depends upon CCR2

(2014) Juyang Kim et al.   JOURNAL OF IMMUNOLOGY

IL-18 Enhances Immunosuppressive Responses by Promoting Differentiation into Monocytic Myeloid-Derived Suppressor Cells

(2014) Hui Xuan Lim et al.   JOURNAL OF IMMUNOLOGY

IL-33 Is an Unconventional Alarmin That Stimulates IL-2 Secretion by Dendritic Cells To Selectively Expand IL-33R/ST2+Regulatory T Cells

(2014) Benjamin M. Matta et al.   JOURNAL OF IMMUNOLOGY

Transgenic expression of IL-33 activates CD8+ T cells and NK cells and inhibits tumor growth and metastasis in mice

(2013) Kun Gao et al.   CANCER LETTERS

Principal role of IL-12p40 in the decreased Th1 and Th17 responses driven by dendritic cells of mice lacking IL-12 and IL-18

(2013) Hui Xuan Lim et al.   CYTOKINE

Polyunsaturated fatty acids promote the expansion of myeloid-derived suppressor cells by activating the JAK/STAT3 pathway

(2013) Dehong Yan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

β-Glucan enhances antitumor immune responses by regulating differentiation and function of monocytic myeloid-derived suppressor cells

(2013) Jie Tian et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells

(2013) Ivan P. Jovanovic et al.   INTERNATIONAL JOURNAL OF CANCER

Myeloid derived suppressor cells (MDSCs) can induce the generation of Th17 response from naïve CD4+ T cells

(2012) Shilpak Chatterjee et al.   IMMUNOBIOLOGY

The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses

(2012) W. V. Bonilla et al.   SCIENCE

ST2 deletion enhances innate and acquired immunity to murine mammary carcinoma

(2011) Ivan Jovanovic et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-33 Expands Suppressive CD11b+ Gr-1int and Regulatory T Cells, including ST2L+ Foxp3+ Cells, and Mediates Regulatory T Cell-Dependent Promotion of Cardiac Allograft Survival

(2011) H. R. Turnquist et al.   JOURNAL OF IMMUNOLOGY

Lineage-Sca1+c-Kit-CD25+ Cells Are IL-33-Responsive Type 2 Innate Cells in the Mouse Bone Marrow

(2011) A. Brickshawana et al.   JOURNAL OF IMMUNOLOGY

The IL-33/ST2 pathway — A new therapeutic target in cardiovascular disease

(2011) Ashley M. Miller et al.   PHARMACOLOGY & THERAPEUTICS

Interleukin-33 prolongs allograft survival during chronic cardiac rejection

(2011) Stefan M. Brunner et al.   TRANSPLANT INTERNATIONAL

The biology of myeloid-derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity

(2010) Je-In Youn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

(2010) Cesar A. Corzo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-33 Exacerbates Autoantibody-Induced Arthritis

(2010) Damo Xu et al.   JOURNAL OF IMMUNOLOGY

Subsets, expansion and activation of myeloid-derived suppressor cells

(2010) Eliana Ribechini et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

(2009) Johanna K. Morales et al.   BREAST CANCER RESEARCH AND TREATMENT

Immune Stimulatory Receptor CD40 Is Required for T-Cell Suppression and T Regulatory Cell Activation Mediated by Myeloid-Derived Suppressor Cells in Cancer

(2009) P.-Y. Pan et al.   CANCER RESEARCH

The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-γ production

(2009) Elvire Bourgeois et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-33–activated dendritic cells induce an atypical TH2-type response

(2009) Matthew A. Rank et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation

(2009) M. Kurowska-Stolarska et al.   JOURNAL OF IMMUNOLOGY

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans

(2008) Carmela De Santo et al.   JOURNAL OF CLINICAL INVESTIGATION