Preconditioning of umbilical cord‐derived mesenchymal stem cells by rapamycin increases cell migration and ameliorates liver ischaemia/reperfusion injury in mice via the CXCR4/CXCL12 axis

Deferoxamine promotes mesenchymal stem cell homing in noise-induced injured cochlea through PI3K/AKT pathway

(2018) A.A. Peyvandi et al.   CELL PROLIFERATION

Autophagy promotes MSC-mediated vascularization in cutaneous wound healing via regulation of VEGF secretion

(2018) Y. An et al.   Cell Death & Disease

Reciprocal role of SIRT6 and Hexokinase 2 in the regulation of autophagy driven monocyte differentiation

(2017) Ankita Singh et al.   EXPERIMENTAL CELL RESEARCH

Autophagy suppresses isoprenaline-induced M2 macrophage polarization via the ROS/ERK and mTOR signaling pathway

(2017) Meihua Shan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Allogeneic bone marrow-derived mesenchymal stromal cells for hepatitis B virus-related acute-on-chronic liver failure: A randomized controlled trial

(2017) Bing-liang Lin et al.   HEPATOLOGY

Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases

(2017) Lushen Li et al.   JOURNAL OF CELL SCIENCE

Resveratrol pretreatment enhanced homing of SDF-1α-preconditioned bone marrow-derived mesenchymal stem cells in a rat model of liver cirrhosis

(2017) Mehrdad Hajinejad et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Infusion of mesenchymal stromal cells after deceased liver transplantation: A phase I–II, open-label, clinical study

(2017) Olivier Detry et al.   JOURNAL OF HEPATOLOGY

Lithocholic acid controls adaptive immune responses by inhibition of Th1 activation through the Vitamin D receptor

(2017) Thijs W. H. Pols et al.   PLoS One

Doxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells

(2017) Sara Beji et al.   Cell Death & Disease

Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function

(2017) Luca Perico et al.   Nature Communications

miR-302b inhibits cancer-related inflammation by targeting ERBB4, IRF2 and CXCR4 in esophageal cancer

(2017) Mingxin Zhang et al.   Oncotarget

Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease

(2017) Samantha F. H. de Witte et al.   Stem Cell Research & Therapy

Preconditioning of bone marrow-derived mesenchymal stromal cells by tetramethylpyrazine enhances cell migration and improves functional recovery after focal cerebral ischemia in rats

(2017) Lin Li et al.   Stem Cell Research & Therapy

Monocytes/Macrophages promote vascular CXCR4 expression via the ERK pathway in hepatocellular carcinoma

(2017) Ya-Ming Meng et al.   OncoImmunology

Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis

(2016) Pierre-Michaël Coly et al.   Autophagy

Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration

(2016) Poh-Shiow Yeh et al.   CANCER LETTERS

All-trans retinoic acid preconditioning enhances proliferation, angiogenesis and migration of mesenchymal stem cellin vitroand enhances wound repairin vivo

(2016) M. Pourjafar et al.   CELL PROLIFERATION

Hypoxia and low-dose inflammatory stimulus synergistically enhance bone marrow mesenchymal stem cell migration

(2016) Yang Yu et al.   CELL PROLIFERATION

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial

(2016) Julián Panés et al.   LANCET

Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression

(2016) Daniela Rovito et al.   Oncotarget

Autophagy Improves the Immunosuppression of CD4+ T Cells by Mesenchymal Stem Cells Through Transforming Growth Factor-β1

(2016) Liangbin Gao et al.   Stem Cells Translational Medicine

Autophagy in SDF-1α-mediated DPSC migration and pulp regeneration

(2015) Jing-wen Yang et al.   BIOMATERIALS

PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma

(2015) Jennifer D. Kubic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Interferon regulatory factor 9 is a key mediator of hepatic ischemia/reperfusion injury

(2015) Pi-Xiao Wang et al.   JOURNAL OF HEPATOLOGY

Engineered Mesenchymal Stem Cells with Enhanced Tropism and Paracrine Secretion of Cytokines and Growth Factors to Treat Traumatic Brain Injury

(2015) Zhe Wang et al.   STEM CELLS

Ultrasound-Targeted Microbubble Destruction Improves the Migration and Homing of Mesenchymal Stem Cells after Myocardial Infarction by Upregulating SDF-1/CXCR4: A Pilot Study

(2015) Lu Li et al.   Stem Cells International

Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination

(2014) Zhenzhen Zhan et al.   Autophagy

Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis

(2014) Shipeng Dang et al.   Autophagy

Strategies to improve homing of mesenchymal stem cells for greater efficacy in stem cell therapy

(2014) Hojjat Naderi-Meshkin et al.   CELL BIOLOGY INTERNATIONAL

Apelin inhibits the proliferation and migration of rat PASMCsviathe activation of PI3K/Akt/mTOR signal and the inhibition of autophagy under hypoxia

(2014) Hongyu Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mesenchymal stromal cells infusions improve refractory chronic graft versus host disease through an increase of CD5+ regulatory B cells producing interleukin 10

(2014) Y Peng et al.   LEUKEMIA

Human adipose–derived mesenchymal stem cells attenuate liver ischemia–reperfusion injury and promote liver regeneration

(2014) Reza F. Saidi et al.   SURGERY

Improvement of ER stress-induced diabetes by stimulating autophagy

(2013) Etty Bachar-Wikstrom et al.   Autophagy

Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: Role of secretome and exosomes

(2013) Marie Maumus et al.   BIOCHIMIE

The mTOR pathway and integrating immune regulation

(2013) Stephen P. Cobbold   IMMUNOLOGY

Migration of CXCR4 gene-modified bone marrow-derived mesenchymal stem cells to the acute injured kidney

(2013) Nanmei Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hepatic ischemia and reperfusion injury: Effects on the liver sinusoidal milieu

(2013) Carmen Peralta et al.   JOURNAL OF HEPATOLOGY

α-Lipoic Acid Reduces Infarct Size and Preserves Cardiac Function in Rat Myocardial Ischemia/Reperfusion Injury through Activation of PI3K/Akt/Nrf2 Pathway

(2013) Chao Deng et al.   PLoS One

Autophagy proteins regulate ERK phosphorylation

(2013) Nuria Martinez-Lopez et al.   Nature Communications

Recombinant protein rVP1 upregulates BECN1-independent autophagy, MAPK1/3 phosphorylation and MMP9 activity via WIPI1/WIPI2 to promote macrophage migration

(2012) Chiao-Chun Liao et al.   Autophagy

Bone marrow mesenchymal stem cells ameliorate hepatic ischemia/reperfusion injuries via inactivation of the MEK/ERK signaling pathway in rats

(2012) Guo-zheng Pan et al.   JOURNAL OF SURGICAL RESEARCH

The Role of SDF-1-CXCR4/CXCR7 Axis in the Therapeutic Effects of Hypoxia-Preconditioned Mesenchymal Stem Cells for Renal Ischemia/Reperfusion Injury

(2012) Hongbao Liu et al.   PLoS One

Engineered cell homing

(2011) D. Sarkar et al.   BLOOD

Autophagy: for better or for worse

(2011) Ellen Wirawan et al.   CELL RESEARCH

Genetically modified adipose tissue−derived mesenchymal stem cells overexpressing CXCR4 display increased motility, invasiveness, and homing to bone marrow of NOD/SCID mice

(2011) Sylwia Bobis-Wozowicz et al.   EXPERIMENTAL HEMATOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

SDF-1α/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model

(2008) Ye Wang et al.   BRAIN RESEARCH

Homing and engraftment of progenitor cells: A prerequisite for cell therapy

(2008) Emmanouil Chavakis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY