Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis

NBR1 enables autophagy-dependent focal adhesion turnover

(2016) Candia M. Kenific et al.   JOURNAL OF CELL BIOLOGY

Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3

(2016) Marina N. Sharifi et al.   Cell Reports

Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells

(2015) Myriam Catalano et al.   Molecular Oncology

Signaling switch of the urotensin II vasosactive peptide GPCR: prototypic chemotaxic mechanism in glioma

(2015) C Lecointre et al.   ONCOGENE

Annexin A2 promotes phagophore assembly by enhancing Atg16L+ vesicle biogenesis and homotypic fusion

(2015) Kateryna Morozova et al.   Nature Communications

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Autophagy and SQSTM1 on the RHOA(d) again

(2014) Amine Belaid et al.   Autophagy

Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition

(2014) Lei Qiang et al.   Autophagy

Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners

(2014) Jun Hoe Kim et al.   Autophagy

Mitochondrial KATP channel involvement in angiotensin II-induced autophagy in vascular smooth muscle cells

(2014) Kang-Ying Yu et al.   BASIC RESEARCH IN CARDIOLOGY

The role of CXCR4 in highly malignant human gliomas biology: Current knowledge and future directions

(2014) Filippo Gagliardi et al.   GLIA

Urotensin II receptor determines prognosis of bladder cancer regulating cell motility/invasion

(2014) Renato Franco et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

CXC chemokine ligand 12 (CXCL12) and its receptor CXCR4

(2014) Takashi Nagasawa   JOURNAL OF MOLECULAR MEDICINE-JMM

SDF1 Reduces Interneuron Leading Process Branching through Dual Regulation of Actin and Microtubules

(2014) D. E. Lysko et al.   JOURNAL OF NEUROSCIENCE

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Regulation of cell proliferation and migration by p62 through stabilization of Twist1

(2014) L. Qiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G protein-coupled receptors and the regulation of autophagy

(2014) Eric M. Wauson et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

PICALM modulates autophagy activity and tau accumulation

(2014) Kevin Moreau et al.   Nature Communications

Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer’s brains

(2013) Kunie Ando et al.   ACTA NEUROPATHOLOGICA

Diverse Autophagosome Membrane Sources Coalesce in Recycling Endosomes

(2013) Claudia Puri et al.   CELL

Autophagy modulates cell migration and β1 integrin membrane recycling

(2013) Véronique Tuloup-Minguez et al.   CELL CYCLE

Urotensin-II receptor is over-expressed in colon cancer cell lines and in colon carcinoma in humans

(2013) Alessandro Federico et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224

(2013) Sheng-Hui Lan et al.   HEPATOLOGY

hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca2+entry and calpain 2

(2013) Nuno Saraiva et al.   JOURNAL OF CELL BIOLOGY

RhoA, RhoB and RhoC have different roles in cancer cell migration

(2013) A.J. RIDLEY   JOURNAL OF MICROSCOPY

Extrasensory perception: Odorant and taste receptors beyond the nose and mouth

(2013) Simon R. Foster et al.   PHARMACOLOGY & THERAPEUTICS

A novel image-based cytometry method for autophagy detection in living cells

(2012) Leo Li-Ying Chan et al.   Autophagy

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

(2012) Julia Romanov et al.   EMBO JOURNAL

Src-dependent autophagic degradation of Ret in FAK-signalling-defective cancer cells

(2012) Emma Sandilands et al.   EMBO REPORTS

The G Protein-Coupled Taste Receptor T1R1/T1R3 Regulates mTORC1 and Autophagy

(2012) Eric M. Wauson et al.   MOLECULAR CELL

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy

(2012) Chinatsu Otomo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RhoB regulates cell migration through altered focal adhesion dynamics

(2012) F. M. Vega et al.   Open Biology

Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis

(2011) Mark A. Eckert et al.   CANCER CELL

Autophagosome Precursor Maturation Requires Homotypic Fusion

(2011) Kevin Moreau et al.   CELL

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling

(2011) Emma Sandilands et al.   NATURE CELL BIOLOGY

ANG II promotes autophagy in podocytes

(2010) Anju Yadav et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

The in vitro cleavage of the hAtg proteins by cell death proteases

(2010) Joanna M. Norman et al.   Autophagy

Control of basal autophagy by calpain1 mediated cleavage of ATG5

(2010) Hong-Guang Xia et al.   Autophagy

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

(2010) Dale W. Hailey et al.   CELL

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

m-calpain Activation Is Regulated by Its Membrane Localization and by Its Binding to Phosphatidylinositol 4,5-Bisphosphate

(2010) Ludovic Leloup et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Urotensin II receptor predicts the clinical outcome of prostate cancer patients and is involved in the regulation of motility of prostate adenocarcinoma cells

(2010) Paolo Grieco et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Angiotensin II Type 2 Receptor Antagonizes Angiotensin II Type 1 Receptor–Mediated Cardiomyocyte Autophagy

(2009) Enzo R. Porrello et al.   HYPERTENSION

Calpain Hydrolysis of α- and β2-Adaptins Decreases Clathrin-dependent Endocytosis and May Promote Neurodegeneration

(2009) Nikita Rudinskiy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early endosomes and endosomal coatomer are required for autophagy

(2009) Minoo Razi et al.   JOURNAL OF CELL BIOLOGY

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

(2009) Mitsuko Hayashi-Nishino et al.   NATURE CELL BIOLOGY

Urotensin II Induces Migration of Endothelial Progenitor Cells via Activation of the RhoA/Rho Kinase Pathway

(2009) Shengkai Xu et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

(2009) Morris E Feldman et al.   PLOS BIOLOGY

CXCL12/CXCR4 signalling in neuronal cell migration

(2008) Marie-Catherine Tiveron et al.   CURRENT OPINION IN NEUROBIOLOGY

Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes

(2008) Jae-Sung Kim et al.   HEPATOLOGY

Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

(2008) Yoshinobu Ichimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY

Urotensin II induces phenotypic differentiation, migration, and collagen synthesis of adventitial fibroblasts from rat aorta

(2008) Yong-Gang Zhang et al.   JOURNAL OF HYPERTENSION

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

(2008) Andrea Williams et al.   Nature Chemical Biology