Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in human hematopoietic stem/progenitor cells

Regulation of Autophagy By Signaling Through the Atg1/ULK1 Complex

(2016) Daniel Papinski et al.   JOURNAL OF MOLECULAR BIOLOGY

Autophagy in the light of sphingolipid metabolism

(2015) Eva Bang Harvald et al.   APOPTOSIS

Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy

(2015) Jason Newton et al.   EXPERIMENTAL CELL RESEARCH

p62/SQSTM1 functions as a signaling hub and an autophagy adaptor

(2015) Yoshinori Katsuragi et al.   FEBS Journal

Autophagy as a Regulatory Component of Erythropoiesis

(2015) Jieying Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase

(2015) Michael V. Airola et al.   STRUCTURE

Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks

(2014) Anne Trécul et al.   BIOCHEMICAL PHARMACOLOGY

p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells

(2014) A Trocoli et al.   CELL DEATH AND DIFFERENTIATION

The generation of neutrophils in the bone marrow is controlled by autophagy

(2014) S Rožman et al.   CELL DEATH AND DIFFERENTIATION

Differential Involvement of I B Kinases   and   in Cytokine- and Insulin-Induced Mammalian Target of Rapamycin Activation Determined by Akt

(2014) H. C. Dan et al.   JOURNAL OF IMMUNOLOGY

Sphingolipid metabolites in inflammatory disease

(2014) Michael Maceyka et al.   NATURE

Autophagy facilitates organelle clearance during differentiation of human erythroblasts

(2013) Virginie M.S. Betin et al.   Autophagy

G-CSF activation of AKT is not sufficient to prolong neutrophil survival

(2013) Liliana R. Souza et al.   JOURNAL OF LEUKOCYTE BIOLOGY

MicroRNA-mediated control of macrophages and its implications for cancer

(2013) Mario Leonardo Squadrito et al.   TRENDS IN IMMUNOLOGY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Tumor necrosis factor alpha-mediated inhibition of erythropoiesis involves GATA-1/GATA-2 balance impairment and PU.1 over-expression

(2011) Christine Grigorakaki et al.   BIOCHEMICAL PHARMACOLOGY

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

(2011) S. Ghani et al.   BLOOD

Autophagy Driven by a Master Regulator of Hematopoiesis

(2011) Y.-A. Kang et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis

(2010) Alberto M. Martelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

MicroRNA-146a disrupts hematopoietic differentiation and survival

(2010) Daniel T. Starczynowski et al.   EXPERIMENTAL HEMATOLOGY

The RUN Domain of Rubicon Is Important for hVps34 Binding, Lipid Kinase Inhibition, and Autophagy Suppression

(2010) Qiming Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PU.1 Positively Regulates GATA-1 Expression in Mast Cells

(2010) C. M. Takemoto et al.   JOURNAL OF IMMUNOLOGY

MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis

(2009) N. Felli et al.   HAEMATOLOGICA

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

(2009) M. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor necrosis factor α inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation

(2008) Isabelle Buck et al.   BIOCHEMICAL PHARMACOLOGY

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

(2008) M. Kundu et al.   BLOOD

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE

A GATA-1-regulated microRNA locus essential for erythropoiesis

(2008) L. C. Dore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA