p53-inducible gene 3 promotes cell migration and invasion by activating the FAK/Src pathway in lung adenocarcinoma

Frequency of Somatic TP53 Mutations in Combination with Known Pathogenic Mutations in Colon Adenocarcinoma, Non–Small Cell Lung Carcinoma, and Gliomas as Identified by Next-Generation Sequencing

(2018) Zahra Shajani-Yi et al.   NEOPLASIA

PIG3 promotes NSCLC cell mitotic progression and is associated with poor prognosis of NSCLC patients

(2017) Ming Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The oncogenic effects of p53-inducible gene 3 (PIG3) in colon cancer cells

(2017) Seon-Joo Park et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Suppression of p53-inducible gene 3 is significant for glioblastoma progression and predicts poor patient prognosis

(2017) Jishu Quan et al.   TUMOR BIOLOGY

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Loss of PIG3 increases HIF-1α level by promoting protein synthesis via mTOR pathway in renal cell carcinoma cells

(2016) Guang Chen et al.   Oncotarget

Advances in Molecular Biology of Lung Disease

(2015) Claire Rooney et al.   CHEST

Lentiviral DDX46 knockdown inhibits growth and induces apoptosis in human colorectal cancer cells

(2015) Ming Li et al.   GENE

A phase I study of VS-6063, a second-generation focal adhesion kinase inhibitor, in patients with advanced solid tumors

(2015) Suzanne F. Jones et al.   INVESTIGATIONAL NEW DRUGS

Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination

(2015) Cecilia Herraiz et al.   JNCI-Journal of the National Cancer Institute

PIG3 plays an oncogenic role in papillary thyroid cancer by activating the PI3K/AKT/PTEN pathway

(2015) JINYE XU et al.   ONCOLOGY REPORTS

Knockdown of long non-coding RNA HOTAIR inhibits proliferation and invasiveness and improves radiosensitivity in colorectal cancer

(2015) XIAO-DONG YANG et al.   ONCOLOGY REPORTS

BRCA1 regulates PIG3-mediated apoptosis in a p53-dependent manner

(2015) Wenwen Zhang et al.   Oncotarget

Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination

(2015) Cecilia Herraiz et al.   JNCI-Journal of the National Cancer Institute

Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)15 motif

(2014) Xiaoxiang Guan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clinicopathologic and prognostic significance of c-MYC copy number gain in lung adenocarcinomas

(2014) A N Seo et al.   BRITISH JOURNAL OF CANCER

Smoking, p53 Mutation, and Lung Cancer

(2014) Don L. Gibbons et al.   MOLECULAR CANCER RESEARCH

Optimizing lung cancer treatment approaches

(2014) Rafael Rosell et al.   Nature Reviews Clinical Oncology

High-Throughput Tyrosine Kinase Activity Profiling Identifies FAK as a Candidate Therapeutic Target in Ewing Sarcoma

(2013) B. D. Crompton et al.   CANCER RESEARCH

Lung Cancer in China

(2013) Jun She et al.   CHEST

PIG3 Functions in DNA Damage Response through Regulating DNA-PKcs Homeostasis

(2013) Bing Li et al.   International Journal of Biological Sciences

FAK and p53 Protein Interactions

(2012) Vita M. Golubovskaya et al.   Anti-Cancer Agents in Medicinal Chemistry

p53-induced Gene 3 Mediates Cell Death Induced by Glutathione Peroxidase 3

(2012) Hui Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Safety, Pharmacokinetic, and Pharmacodynamic Phase I Dose-Escalation Trial of PF-00562271, an Inhibitor of Focal Adhesion Kinase, in Advanced Solid Tumors

(2012) Jeffrey R. Infante et al.   JOURNAL OF CLINICAL ONCOLOGY

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2012) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

p53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines

(2010) Suresh Anaganti et al.   CANCER LETTERS

Three-dimensional Structure and Enzymatic Function of Proapoptotic Human p53-inducible Quinone Oxidoreductase PIG3

(2009) Sergio Porté et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p53-inducible gene 3 (PIG3) contributes to early cellular response to DNA damage

(2009) J-H Lee et al.   ONCOGENE

Compartmentalization of Redox Signaling Through NADPH Oxidase–Derived ROS

(2008) Masuko Ushio-Fukai   ANTIOXIDANTS & REDOX SIGNALING

Nuclear FAK Promotes Cell Proliferation and Survival through FERM-Enhanced p53 Degradation

(2008) Ssang-Taek Lim et al.   MOLECULAR CELL

p53 regulates FAK expression in human tumor cells

(2007) Vita M. Golubovskaya et al.   MOLECULAR CARCINOGENESIS