PIG3 promotes NSCLC cell mitotic progression and is associated with poor prognosis of NSCLC patients

Mucin 1-mediated chemo-resistance in lung cancer cells

(2016) S Y Ham et al.   Oncogenesis

Impact of KRAS codon subtypes from a randomised phase II trial of selumetinib plus docetaxel in KRAS mutant advanced non-small-cell lung cancer

(2015) P A Jänne et al.   BRITISH JOURNAL OF CANCER

Advances in Molecular Biology of Lung Disease

(2015) Claire Rooney et al.   CHEST

Lentiviral DDX46 knockdown inhibits growth and induces apoptosis in human colorectal cancer cells

(2015) Ming Li et al.   GENE

BRCA1 regulates PIG3-mediated apoptosis in a p53-dependent manner

(2015) Wenwen Zhang et al.   Oncotarget

NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor

(2015) Lan Yu et al.   Oncotarget

The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry

(2015) Kyung-Jong Lee et al.   NEOPLASIA

Polo-like kinase 1 (PLK1) and protein phosphatase 6 (PP6) regulate DNA-dependent protein kinase catalytic subunit (DNA-PKcs) phosphorylation in mitosis

(2014) Pauline Douglas et al.   BIOSCIENCE REPORTS

Clinicopathologic and prognostic significance of c-MYC copy number gain in lung adenocarcinomas

(2014) A N Seo et al.   BRITISH JOURNAL OF CANCER

Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells

(2014) Norman Ertych et al.   NATURE CELL BIOLOGY

Optimizing lung cancer treatment approaches

(2014) Rafael Rosell et al.   Nature Reviews Clinical Oncology

DNA-PKcs activates the Chk2–Brca1 pathway during mitosis to ensure chromosomal stability

(2014) Z Shang et al.   Oncogenesis

NQO1 prevents radiation-induced aneuploidy by interacting with Aurora-A

(2013) Moon-Taek Park et al.   CARCINOGENESIS

PIG3 Functions in DNA Damage Response through Regulating DNA-PKcs Homeostasis

(2013) Bing Li et al.   International Journal of Biological Sciences

DNA-PKcs Associates With PLK1 and Is Involved in Proper Chromosome Segregation and Cytokinesis

(2013) Bo Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Over-expression of survivin and VEGF in small-cell lung cancer may predict the poorer prognosis

(2013) Ping Chen et al.   MEDICAL ONCOLOGY

Functional repeats (TGYCC)n in the p53-inducible gene 3 ( PIG3 ) promoter and susceptibility to squamous cell carcinoma of the head and neck

(2012) Xiaoxiang Guan et al.   CARCINOGENESIS

4E-BP1 participates in maintaining spindle integrity and genomic stability via interacting with PLK1

(2012) Zeng-Fu Shang et al.   CELL CYCLE

The critical role of catalase in prooxidant and antioxidant function of p53

(2012) M Y Kang et al.   CELL DEATH AND DIFFERENTIATION

Global burden of cancer in 2008: a systematic analysis of disability-adjusted life-years in 12 world regions

(2012) Isabelle Soerjomataram et al.   LANCET

NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Localizes to the Mitotic Spindle in Human Cells

(2012) David Siegel et al.   PLoS One

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PIG3: A novel link between oxidative stress and DNA damage response in cancer

(2011) Athanassios Kotsinas et al.   CANCER LETTERS

Involvement of DNA-dependent Protein Kinase in Normal Cell Cycle Progression through Mitosis

(2011) Kyung-Jong Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of DNA-Dependent Protein Kinase Leads to Spindle Disruption and Mitotic Catastrophe with Attenuated Checkpoint Protein 2 Phosphorylation in Response to DNA Damage

(2010) Zeng-Fu Shang et al.   CANCER RESEARCH

Cytokinesis failure and attenuation: new findings in Fanconi anemia

(2010) Philip J. Mason et al.   JOURNAL OF CLINICAL INVESTIGATION

Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice

(2009) C. V. Rao et al.   CARCINOGENESIS

Three-dimensional Structure and Enzymatic Function of Proapoptotic Human p53-inducible Quinone Oxidoreductase PIG3

(2009) Sergio Porté et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p53-inducible gene 3 (PIG3) contributes to early cellular response to DNA damage

(2009) J-H Lee et al.   ONCOGENE