Combinations of BRAF inhibitor and anti-PD-1/PD-L1 antibody improve survival and tumour immunity in an immunocompetent model of orthotopic murine anaplastic thyroid cancer

Real-World Experience with Targeted Therapy for the Treatment of Anaplastic Thyroid Carcinoma

(2018) Priyanka C. Iyer et al.   THYROID

Phase I/II study of spartalizumab (PDR001), an anti-PD1 mAb, in patients with anaplastic thyroid cancer.

(2018) Lori J. Wirth et al.   JOURNAL OF CLINICAL ONCOLOGY

Genomic complexity and targeted genes in anaplastic thyroid cancer cell lines

(2017) Eleanor L Woodward et al.   ENDOCRINE-RELATED CANCER

Comprehensive screening for PD-L1 expression in thyroid cancer

(2017) Soomin Ahn et al.   ENDOCRINE-RELATED CANCER

Expression of PD-1 and PD-L1 in Anaplastic Thyroid Cancer Patients Treated With Multimodal Therapy: Results From a Retrospective Study

(2017) Ashish V. Chintakuntlawar et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

(2017) Sydney R. Gordon et al.   NATURE

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Real-Time Genomic Characterization Utilizing Circulating Cell-Free DNA in Patients with Anaplastic Thyroid Carcinoma

(2017) Vlad C. Sandulache et al.   THYROID

Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

(2017) Sathana Dushyanthen et al.   Nature Communications

Non-Invasive Monitoring of CNS MHC-I Molecules in Ischemic Stroke Mice

(2017) Jing Xia et al.   Theranostics

Leveraging the immune system to treat advanced thyroid cancers

(2017) Jena D French et al.   Lancet Diabetes & Endocrinology

Human Tumor-Infiltrating Myeloid Cells: Phenotypic and Functional Diversity

(2017) Louise A. Elliott et al.   Frontiers in Immunology

Genome-wide association analysis identifies genetic correlates of immune infiltrates in solid tumors

(2017) Nathan O. Siemers et al.   PLoS One

2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: What is new and what has changed?

(2016) Bryan R. Haugen   CANCER

Tumor-Infiltrating T Cells and the PD-1 Checkpoint Pathway in Advanced Differentiated and Anaplastic Thyroid Cancer

(2016) Jill J. Bastman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Evolving molecularly targeted therapies for advanced-stage thyroid cancers

(2016) Keith C. Bible et al.   Nature Reviews Clinical Oncology

Biologic and Clinical Perspectives on Thyroid Cancer

(2016) James A. Fagin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Circulating Myeloid-Derived Suppressor Cells Predict Differentiated Thyroid Cancer Diagnosis and Extent

(2016) Trevor E. Angell et al.   THYROID

Learning from PD-1 Resistance: New Combination Strategies

(2016) Xia Bu et al.   TRENDS IN MOLECULAR MEDICINE

Combining BRAF inhibitor and anti PD-L1 antibody dramatically improves tumor regression and anti tumor immunity in an immunocompetent murine model of anaplastic thyroid cancer

(2016) Eran Brauner et al.   Oncotarget

Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy

(2016) Maarten Swart et al.   Frontiers in Oncology

Anaplastic Thyroid Carcinoma: Treatment in the Age of Molecular Targeted Therapy

(2016) Maria E. Cabanillas et al.   Journal of Oncology Practice

BRAFV600E in Papillary Thyroid Carcinoma Is Associated with Increased Programmed Death Ligand 1 Expression and Suppressive Immune Cell Infiltration

(2014) Trevor E. Angell et al.   THYROID

The Immune Microenvironment Confers Resistance to MAPK Pathway Inhibitors through Macrophage-Derived TNF 

(2014) M. P. Smith et al.   Cancer Discovery

The Next Generation of Orthotopic Thyroid Cancer Models: Immunocompetent Orthotopic Mouse Models of BRAFV600E-Positive Papillary and Anaplastic Thyroid Carcinoma

(2013) Pierre Vanden Borre et al.   THYROID

MAP Kinase Pathway Alterations in BRAF-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition

(2013) N. Wagle et al.   Cancer Discovery

American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer

(2012) Robert C. Smallridge et al.   THYROID

Targeting BRAFV600E with PLX4720 Displays Potent Antimigratory and Anti-invasive Activity in Preclinical Models of Human Thyroid Cancer

(2011) C. Nucera et al.   ONCOLOGIST

Tumor-Associated Macrophages (TAMs) Form an Interconnected Cellular Supportive Network in Anaplastic Thyroid Carcinoma

(2011) Bernard Caillou et al.   PLoS One

Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer

(2008) M. Ryder et al.   ENDOCRINE-RELATED CANCER

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(2008) Ryan L. Neff et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Functions of natural killer cells

(2008) Eric Vivier et al.   NATURE IMMUNOLOGY