PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPARγ SUMOylation

Identification of a new small ubiquitin-like modifier (SUMO)-interacting motif in the E3 ligase PIASy

(2017) Kawaljit Kaur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMO-specific protease 1 protects neurons from apoptotic death during transient brain ischemia/reperfusion

(2016) Huijun Zhang et al.   Cell Death & Disease

Specific regulation of PRMT1 expression by PIAS1 and RKIP in BEAS-2B epithelia cells and HFL-1 fibroblasts in lung inflammation

(2016) Li Liu et al.   Scientific Reports

Activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ) Through NF-κB/Brg1 and TGF-ß1 Pathways Attenuates Cardiac Remodeling in Pressure-Overloaded Rat Hearts

(2015) Han-Ping Qi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

PIAS-like protein Zimp7 is required for the restriction of the zebrafish organizer and mesoderm development

(2015) Roberto Moreno-Ayala et al.   DEVELOPMENTAL BIOLOGY

Protein Inhibitor of Activated STAT 1 (PIAS1) Protects Against Obesity-Induced Insulin Resistance by Inhibiting Inflammation Cascade in Adipose Tissue

(2015) Yang Liu et al.   DIABETES

The SUMO (Small Ubiquitin-like Modifier) Ligase PIAS3 Primes ATR for Checkpoint Activation

(2015) Ching-Shyi Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mangiferin Mitigates Gastric Ulcer in Ischemia/ Reperfused Rats: Involvement of PPAR-γ, NF-κB and Nrf2/HO-1 Signaling Pathways

(2015) Magdy Mahmoud-Awny et al.   PLoS One

SENP1 protects against myocardial ischaemia/reperfusion injury via a HIF1α-dependent pathway

(2014) Jianmin Gu et al.   CARDIOVASCULAR RESEARCH

The Role of SUMO-Conjugating Enzyme Ubc9 in the Neuroprotection of Isoflurane Preconditioning Against Ischemic Neuronal Injury

(2014) Li Tong et al.   MOLECULAR NEUROBIOLOGY

Necdin Promotes Ubiquitin-Dependent Degradation of PIAS1 SUMO E3 Ligase

(2014) Ibrahim Gur et al.   PLoS One

Hesperidin Produces Cardioprotective Activity via PPAR-γ Pathway in Ischemic Heart Disease Model in Diabetic Rats

(2014) Yogeeta O. Agrawal et al.   PLoS One

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

Myocardial ischemia-reperfusion injury: a neglected therapeutic target

(2013) Derek J. Hausenloy et al.   JOURNAL OF CLINICAL INVESTIGATION

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

Quercetin Inhibits Left Ventricular Hypertrophy in Spontaneously Hypertensive Rats and Inhibits Angiotensin II-Induced H9C2 Cells Hypertrophy by Enhancing PPAR-γ Expression and Suppressing AP-1 Activity

(2013) Lei Yan et al.   PLoS One

Inflammation in Myocardial Diseases

(2012) David J. Marchant et al.   CIRCULATION RESEARCH

A potent soluble epoxide hydrolase inhibitor, t-AUCB, acts through PPARγ to modulate the function of endothelial progenitor cells from patients with acute myocardial infarction

(2012) Dan-yan Xu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

An Acetylation Switch Regulates SUMO-Dependent Protein Interaction Networks

(2012) Rebecca Ullmann et al.   MOLECULAR CELL

Function and regulation of SUMO proteases

(2012) Christopher M. Hickey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PPARs and Lipid Ligands in Inflammation and Metabolism

(2011) Gregory S. Harmon et al.   CHEMICAL REVIEWS

Liver X receptor negatively regulates fibroblast growth factor 21 in the fatty liver induced by cholesterol-enriched diet

(2011) Takashi Uebanso et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

PIAS proteins: pleiotropic interactors associated with SUMO

(2009) Miia M. Rytinki et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reperfusion Injury, Microvascular Dysfunction, and Cardioprotection

(2009) Abhiram Prasad et al.   CIRCULATION