Iron deficiency

Modulation of intestinal sulfur assimilation metabolism regulates iron homeostasis

(2018) Benjamin H. Hudson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk

(2018) De-Liang Zhang et al.   SCIENCE

Efficacy of iron supplementation on fatigue and physical capacity in non-anaemic iron-deficient adults: a systematic review of randomised controlled trials

(2018) Brett L Houston et al.   BMJ Open

Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals

(2017) Anthony S. Grillo et al.   SCIENCE

How I treat anemia in pregnancy: iron, cobalamin, and folate

(2016) Maureen M. Achebe et al.   BLOOD

Hepcidin in the diagnosis of iron disorders

(2016) D. Girelli et al.   BLOOD

Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD

(2016) Thomas Lee et al.   GUT

Iron management in chronic kidney disease: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

(2016) Iain C. Macdougall et al.   KIDNEY INTERNATIONAL

Iron deficiency anaemia

(2016) Anthony Lopez et al.   LANCET

So you know how to treat iron deficiency anemia

(2015) S. L. Schrier   BLOOD

Oral iron supplements increase hepcidin and decrease iron absorption from daily or twice-daily doses in iron-depleted young women

(2015) D. Moretti et al.   BLOOD

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

(2015) A. Pagani et al.   HAEMATOLOGICA

Ferric Maltol Is Effective in Correcting Iron Deficiency Anemia in Patients with Inflammatory Bowel Disease

(2015) Christoph Gasche et al.   INFLAMMATORY BOWEL DISEASES

The Safety of Intravenous Iron Preparations

(2015) Tomer Avni et al.   MAYO CLINIC PROCEEDINGS

Iron-Deficiency Anemia

(2015) Clara Camaschella   NEW ENGLAND JOURNAL OF MEDICINE

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

(2015) Joseph D Mancias et al.   eLife

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

(2015) A. Pagani et al.   HAEMATOLOGICA

Ferrous Sulfate Supplementation Causes Significant Gastrointestinal Side-Effects in Adults: A Systematic Review and Meta-Analysis

(2015) Zoe Tolkien et al.   PLoS One

The second transferrin receptor regulates red blood cell production in mice

(2014) A. Nai et al.   BLOOD

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

(2014) Thomas Sonnweber et al.   GUT

Iron fortification adversely affects the gut microbiome, increases pathogen abundance and induces intestinal inflammation in Kenyan infants

(2014) Tanja Jaeggi et al.   GUT

Hypersensitivity reactions to intravenous iron: guidance for risk minimization and management

(2014) D. Rampton et al.   HAEMATOLOGICA

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Identification of erythroferrone as an erythroid regulator of iron metabolism

(2014) Léon Kautz et al.   NATURE GENETICS

FIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia

(2014) I. C. Macdougall et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effect of oral liposomal iron versus intravenous iron for treatment of iron deficiency anaemia in CKD patients: a randomized trial

(2014) A. Pisani et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

(2014) Beben Benyamin et al.   Nature Communications

Host iron status and iron supplementation mediate susceptibility to erythrocytic stage Plasmodium falciparum

(2014) Martha A. Clark et al.   Nature Communications

The physiological functions of iron regulatory proteins in iron homeostasis - an update

(2014) De-Liang Zhang et al.   Frontiers in Pharmacology

The prevalence and impact of restless legs syndrome on patients with iron deficiency anemia

(2013) Richard P. Allen et al.   AMERICAN JOURNAL OF HEMATOLOGY

How I treat unexplained refractory iron deficiency anemia

(2013) C. Hershko et al.   BLOOD

The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions

(2013) M. Mastrogiannaki et al.   BLOOD

A systematic analysis of global anemia burden from 1990 to 2010

(2013) N. J. Kassebaum et al.   BLOOD

The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption

(2013) Sheila A. Anderson et al.   Cell Metabolism

Deletion of Iron Regulatory Protein 1 Causes Polycythemia and Pulmonary Hypertension in Mice through Translational Derepression of HIF2α

(2013) Manik C. Ghosh et al.   Cell Metabolism

Anaemia and cognitive performances in the elderly: a systematic review

(2013) M. Andro et al.   EUROPEAN JOURNAL OF NEUROLOGY

Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response

(2013) Chanté L. Richardson et al.   JOURNAL OF CLINICAL INVESTIGATION

Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials

(2013) E. Litton et al.   BMJ-British Medical Journal

Hepcidin is the major predictor of erythrocyte iron incorporation in anemic African children

(2012) A. M. Prentice et al.   BLOOD

mTOR Regulates Cellular Iron Homeostasis through Tristetraprolin

(2012) Marina Bayeva et al.   Cell Metabolism

Iron Deficiency Protects Against Severe Plasmodium falciparum Malaria and Death in Young Children

(2012) M. Gwamaka et al.   CLINICAL INFECTIOUS DISEASES

Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration

(2011) P.-A. Krayenbuehl et al.   BLOOD

Profile of altered brain iron acquisition in restless legs syndrome

(2011) J. R. Connor et al.   BRAIN

Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations

(2011) M. Traglia et al.   JOURNAL OF MEDICAL GENETICS

Clinical Use of Intravenous Iron: Administration, Efficacy, and Safety

(2011) M. Auerbach et al.   Hematology-American Society of Hematology Education Program

The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Côte d'Ivoire

(2010) Michael B Zimmermann et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Iron control of erythroid development by a novel aconitase-associated regulatory pathway

(2010) G. C. Bullock et al.   BLOOD

The effects of oral iron supplementation on cognition in older children and adults: a systematic review and meta-analysis

(2010) Martin Falkingham et al.   Nutrition Journal

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

(2009) Nicole Soranzo et al.   NATURE GENETICS

Ferric Carboxymaltose in Patients with Heart Failure and Iron Deficiency

(2009) Stefan D. Anker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

(2008) A. R. Folgueras et al.   BLOOD

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

(2008) L. Kautz et al.   BLOOD

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

(2008) Laura Silvestri et al.   Cell Metabolism

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

(2008) X. Du et al.   SCIENCE