LipG a bifunctional phospholipase/thioesterase involved in mycobacterial envelope remodeling

Cyclophostin and Cyclipostins analogues, new promising molecules to treat mycobacterial-related diseases

(2018) Phuong Chi Nguyen et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Cyclipostins and cyclophostin analogs inhibit the antigen 85C fromMycobacterium tuberculosisbothin vitroandin vivo

(2018) Albertus Viljoen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rv0646c, an esterase from M. tuberculosis, up-regulates the host immune response in THP-1 macrophages cells

(2018) Ruchi Rastogi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis

(2018) Phuong Chi Nguyen et al.   BIOORGANIC CHEMISTRY

Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in Mycobacterium tuberculosis

(2018) Phuong Chi Nguyen et al.   JOURNAL OF MOLECULAR BIOLOGY

Multifaceted role of lipids in Mycobacterium leprae

(2017) Gurkamaljit Kaur et al.   Future Microbiology

Inflammatory stimuli induce acyl-CoA thioesterase 7 and remodeling of phospholipids containing unsaturated long (≥C20)-acyl chains in macrophages

(2017) Valerie Z. Wall et al.   JOURNAL OF LIPID RESEARCH

Green Fluorescent Protein as a protein localization and topological reporter in mycobacteria

(2017) Juan Manuel Belardinelli et al.   TUBERCULOSIS

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis

(2017) Phuong Chi Nguyen et al.   Scientific Reports

New lipase assay using Pomegranate oil coating in microtiter plates

(2016) Serdar Ülker et al.   BIOCHIMIE

A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery

(2016) Nicolas Flaugnatti et al.   MOLECULAR MICROBIOLOGY

Synthesis and comparison of the biological activity of monocyclic phosphonate, difluorophosphonate and phosphate analogs of the natural AChE inhibitor cyclophostin

(2015) Benjamin P. Martin et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Rat hormone sensitive lipase inhibition by cyclipostins and their analogs

(2015) Elena Vasilieva et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The interactions of peripheral membrane proteins with biological membranes

(2015) A.M. Whited et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Mechanisms of drug resistance in Mycobacterium tuberculosis: update 2015

(2015) Y. Zhang et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

The cell envelope of tubercle bacilli

(2015) Mamadou Daffé   TUBERCULOSIS

Mycolic Acids: Structures, Biosynthesis, and Beyond

(2014) Hedia Marrakchi et al.   CHEMISTRY & BIOLOGY

New Approaches to Target the Mycolic Acid Biosynthesis Pathway for the Development of Tuberculosis Therapeutics

(2014) E. North et al.   CURRENT PHARMACEUTICAL DESIGN

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Targeting Lipid Esterases in Mycobacteria Grown Under Different Physiological Conditions Using Activity-based Profiling with Tetrahydrolipstatin (THL)

(2013) Madhu Sudhan Ravindran et al.   MOLECULAR & CELLULAR PROTEOMICS

Advances in the development of new tuberculosis drugs and treatment regimens

(2013) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

Identification of Residues Involved in Substrate Specificity and Cytotoxicity of Two Closely Related Cutinases from Mycobacterium tuberculosis

(2013) Luc Dedieu et al.   PLoS One

Mycobacterial lipolytic enzymes: A gold mine for tuberculosis research

(2012) L. Dedieu et al.   BIOCHIMIE

Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases

(2012) Vanessa Point et al.   JOURNAL OF MEDICINAL CHEMISTRY

MmPPOX Inhibits Mycobacterium tuberculosis Lipolytic Enzymes Belonging to the Hormone-Sensitive Lipase Family and Alters Mycobacterial Growth

(2012) Vincent Delorme et al.   PLoS One

The Mycobacterium tuberculosis Very-Long-Chain Fatty Acyl-CoA Synthetase: Structural Basis for Housing Lipid Substrates Longer than the Enzyme

(2012) Charlotta S. Andersson et al.   STRUCTURE

Improved mycobacterial protein production using a Mycobacterium smegmatis groEL1ΔC expression strain

(2011) Elke E Noens et al.   BMC BIOTECHNOLOGY

Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) Protein Domains Target LipY Lipases of Pathogenic Mycobacteria to the Cell Surface via the ESX-5 Pathway

(2011) Maria H. Daleke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterium tuberculosis Lipolytic Enzymes as Potential Biomarkers for the Diagnosis of Active Tuberculosis

(2011) Belinda Brust et al.   PLoS One

The Mycobacterium Tuberculosis FAS-II Dehydratases and Methyltransferases Define the Specificity of the Mycolic Acid Elongation Complexes

(2011) Sylvain Cantaloube et al.   PLoS One

Recent advances in deciphering the contribution of Mycobacterium tuberculosis lipids to pathogenesis

(2011) Olivier Neyrolles et al.   TUBERCULOSIS

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

A Monoacylglycerol Lipase from Mycobacterium smegmatis Involved in Bacterial Cell Interaction

(2010) R. Dhouib et al.   JOURNAL OF BACTERIOLOGY

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

The MycoBrowser portal: A comprehensive and manually annotated resource for mycobacterial genomes

(2010) Adamandia Kapopoulou et al.   TUBERCULOSIS

Emergence of New Forms of Totally Drug-Resistant Tuberculosis Bacilli

(2009) Ali Akbar Velayati et al.   CHEST

Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identification

(2009) Nicholas P. West et al.   FASEB JOURNAL

Identification of a Stress-Induced Factor of Corynebacterineae That Is Involved in the Regulation of the Outer Membrane Lipid Composition

(2009) X. Meniche et al.   JOURNAL OF BACTERIOLOGY

Mycobacterium tuberculosis Rv3802c Encodes a Phospholipase/Thioesterase and Is Inhibited by the Antimycobacterial Agent Tetrahydrolipstatin

(2009) Sarah K. Parker et al.   PLoS One

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS