Targeting Lipid Esterases in Mycobacteria Grown Under Different Physiological Conditions Using Activity-based Profiling with Tetrahydrolipstatin (THL)

Mycobacterial lipolytic enzymes: A gold mine for tuberculosis research

(2012) L. Dedieu et al.   BIOCHIMIE

Parasite-Based Screening and Proteome Profiling Reveal Orlistat, an FDA-Approved Drug, as a Potential Anti Trypanosoma brucei Agent[]

(2012) Peng-Yu Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Activity-based protein profiling: an enabling technology in chemical biology research

(2012) Nan Li et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Systematic investigation of protein-small molecule interactions

(2012) Xiyan Li et al.   IUBMB LIFE

Wax Ester Synthesis is Required for Mycobacterium tuberculosis to Enter In Vitro Dormancy

(2012) Tatiana D. Sirakova et al.   PLoS One

Bioinformatic analysis of alpha/beta-hydrolase fold enzymes reveals subfamily-specific positions responsible for discrimination of amidase and lipase activities

(2012) D. A. Suplatov et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Linking the Transcriptional Profiles and the Physiological States of Mycobacterium tuberculosis during an Extended Intracellular Infection

(2012) Kyle H. Rohde et al.   PLoS Pathogens

LipC (Rv0220) Is an Immunogenic Cell Surface Esterase of Mycobacterium tuberculosis

(2011) Guomiao Shen et al.   INFECTION AND IMMUNITY

Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway inStreptomyces coelicolor

(2011) Jonathan R. Whicher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atomic-Level Protein Structure Refinement Using Fragment-Guided Molecular Dynamics Conformation Sampling

(2011) Jian Zhang et al.   STRUCTURE

A Role for Phosphatidic Acid in the Formation of “Supersized” Lipid Droplets

(2011) Weihua Fei et al.   PLoS Genetics

Letting Sleeping dos Lie: Does Dormancy Play a Role in Tuberculosis?

(2010) Michael C. Chao et al.   Annual Review of Microbiology

Click-based synthesis and proteomic profiling of lipstatin analogues

(2010) Mun H. Ngai et al.   CHEMICAL COMMUNICATIONS

Lipid hydrolizing enzymes in virulence:Mycobacterium tuberculosisas a model system

(2010) Gurdyal Singh et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Lipid Droplet-associated Proteins Are Involved in the Biosynthesis and Hydrolysis of Triacylglycerol inMycobacterium bovisBacillus Calmette-Guérin

(2010) Kai Leng Low et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics

(2010) Guanghou Shui et al.   Molecular BioSystems

Carbon flux rerouting during Mycobacterium tuberculosis growth arrest

(2010) Lanbo Shi et al.   MOLECULAR MICROBIOLOGY

A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae

(2010) Oriol Gallego et al.   Molecular Systems Biology

DosR-regulon genes induction in Mycobacterium bovis BCG under aerobic conditions

(2010) Mario Alberto Flores Valdez et al.   TUBERCULOSIS

Triacylglycerol Utilization Is Required for Regrowth of In Vitro Hypoxic Nonreplicating Mycobacterium bovis Bacillus Calmette-Guerin

(2009) K. L. Low et al.   JOURNAL OF BACTERIOLOGY

Activity-Based Proteome Profiling of Potential Cellular Targets of Orlistat − An FDA-Approved Drug with Anti-Tumor Activities

(2009) Peng-Yu Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Foamy macrophages and the progression of the human tuberculosis granuloma

(2009) David G Russell et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis Rv3802c Encodes a Phospholipase/Thioesterase and Is Inhibited by the Antimycobacterial Agent Tetrahydrolipstatin

(2009) Sarah K. Parker et al.   PLoS One

A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen

(2009) Chirajyoti Deb et al.   PLoS One

Live Cell Multicolor Imaging of Lipid Droplets with a New Dye, LD540

(2009) Johanna Spandl et al.   TRAFFIC

Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic Pathway

(2008) Heather B. Claxton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Comparative Study of Electrostatic Repulsion-Hydrophilic Interaction Chromatography (ERLIC) versus SCX-IMAC-Based Methods for Phosphopeptide Isolation/Enrichment

(2008) Chee Sian Gan et al.   JOURNAL OF PROTEOME RESEARCH

Growth pattern and partial proteome of Mycobacterium avium subsp. paratuberculosis during the stress response to hypoxia and nutrient starvation

(2008) Sanjeev Gumber et al.   VETERINARY MICROBIOLOGY