A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence

RAB27B requirement for stretch-induced exocytosis in bladder umbrella cells

(2018) Luciana I. Gallo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanisms and function of autophagy in intestinal disease

(2018) Kara G. Lassen et al.   Autophagy

The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A

(2018) Claudia Puri et al.   DEVELOPMENTAL CELL

The WD40 domain of ATG16L1 is required for its non‐canonical role in lipidation of LC3 at single membranes

(2018) Katherine Fletcher et al.   EMBO JOURNAL

Genetic control of autophagy underlies pathogenesis of inflammatory bowel disease

(2017) K G Lassen et al.   Mucosal Immunology

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine

(2017) Shai Bel et al.   SCIENCE

Ferritinophagy drives uropathogenicEscherichia colipersistence in bladder epithelial cells

(2016) Kyle A. Bauckman et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis

(2016) Qun Lu et al.   Cell Host & Microbe

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation

(2016) Sunmin Park et al.   Cell Host & Microbe

Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells

(2016) Bret Wankel et al.   MOLECULAR BIOLOGY OF THE CELL

The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1

(2016) Emilio Boada-Romero et al.   Nature Communications

The urothelium: Anatomy, review of the literature, perspectives for veterinary medicine

(2015) S. Arrighi   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion

(2015) Yuxuan Miao et al.   CELL

Selective autophagy: Xenophagy

(2015) Kyle A. Bauckman et al.   METHODS

ATG16L1 deficiency in macrophages drives clearance of uropathogenic E. coli in an IL-1β-dependent manner

(2015) J W Symington et al.   Mucosal Immunology

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

(2015) Jacqueline M. Kimmey et al.   NATURE

Direct link between Atg protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals

(2014) Mitsunori Fukuda et al.   Autophagy

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

(2014) Aditya Murthy et al.   NATURE

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

(2014) K. G. Lassen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role ofEpg5in selective neurodegeneration and Vici syndrome

(2013) Yan G. Zhao et al.   Autophagy

Retinoid Signaling in Progenitors Controls Specification and Regeneration of the Urothelium

(2013) Devangini Gandhi et al.   DEVELOPMENTAL CELL

Urinary Tract Infection Syndromes

(2013) Betsy Foxman   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Mice deficient inEpg5exhibit selective neuronal vulnerability to degeneration

(2013) Hongyu Zhao et al.   JOURNAL OF CELL BIOLOGY

The return of the nucleus: transcriptional and epigenetic control of autophagy

(2013) Jens Füllgrabe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Crohn's disease: associated ATG16L1 variant andSalmonellainvasion

(2013) Jeannette S Messer et al.   BMJ Open

ATG16L1 and pathogenesis of urinary tract infections

(2012) Caihong Wang et al.   Autophagy

The triumph of good over evil: protection by the sickle gene against malaria

(2012) H. F. Bunn   BLOOD

Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

(2012) Seungmin Hwang et al.   Cell Host & Microbe

Selective Subversion of Autophagy Complexes Facilitates Completion of the Brucella Intracellular Cycle

(2012) Tregei Starr et al.   Cell Host & Microbe

Atg16L1 deficiency confers protection from uropathogenic Escherichia coli infection in vivo

(2012) C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Crohn's Disease Susceptibility Gene Interactions, a NOD to the Newcomer ATG16L1

(2010) Ken Cadwell   GASTROENTEROLOGY

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Dimeric Coiled-coil Structure ofSaccharomyces cerevisiaeAtg16 and Its Functional Significance in Autophagy

(2009) Yuko Fujioka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy

(2009) Naonobu Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAB26 and RAB3D Are Direct Transcriptional Targets of MIST1 That Regulate Exocrine Granule Maturation

(2009) X. Tian et al.   MOLECULAR AND CELLULAR BIOLOGY

Involvement of Vps33a in the Fusion of Uroplakin-Degrading Multivesicular Bodies with Lysosomes

(2009) Xuemei Guo et al.   TRAFFIC

Phosphonocarboxylates Inhibit the Second Geranylgeranyl Addition by Rab Geranylgeranyl Transferase

(2008) Rudi A. Baron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation

(2008) Takashi Itoh et al.   MOLECULAR BIOLOGY OF THE CELL

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant

(2008) Petric Kuballa et al.   PLoS One

Rab11a-dependent exocytosis of discoidal/fusiform vesicles in bladder umbrella cells

(2008) P. Khandelwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA