The metalloprotease ADAMTS4 generates N-truncated Aβ4–x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer’s disease
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The metalloprotease ADAMTS4 generates N-truncated Aβ4–x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer’s disease
Authors
Keywords
-
Journal
ACTA NEUROPATHOLOGICA
Volume -, Issue -, Pages -
Publisher
Springer Nature America, Inc
Online
2018-11-13
DOI
10.1007/s00401-018-1929-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition
- (2018) Erwin Cabrera et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- GWAS on family history of Alzheimer’s disease
- (2018) Riccardo E. Marioni et al. Translational Psychiatry
- White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes
- (2018) Sara E. Nasrabady et al. Acta Neuropathologica Communications
- Increased metalloproteinase activity in the hippocampus following status epilepticus
- (2017) Deepti Dubey et al. EPILEPSY RESEARCH
- ADAMTS-4 in oligodendrocytes contributes to myelination with an impact on motor function
- (2017) Mathilde Pruvost et al. GLIA
- Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production
- (2017) Hermeto Gerber et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-truncated Aβ4–x peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models
- (2017) Oliver Wirths et al. Alzheimers Research & Therapy
- Functional Roles of the Interaction of APP and Lipoprotein Receptors
- (2017) Theresa Pohlkamp et al. Frontiers in Molecular Neuroscience
- 2016 Alzheimer's disease facts and figures
- (2016) Alzheimers & Dementia
- White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network
- (2016) Seonjoo Lee et al. ANNALS OF NEUROLOGY
- The Cellular Phase of Alzheimer’s Disease
- (2016) Bart De Strooper et al. CELL
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis
- (2016) Sighild Lemarchant et al. Molecular Neurodegeneration
- Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site
- (2016) Caroline Schönherr et al. Molecular Neurodegeneration
- Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer’s disease and transgenic mouse models
- (2016) Jochim Reinert et al. Acta Neuropathologica Communications
- Quantitative detection of amyloid-β peptides by mass spectrometry: state of the art and clinical applications
- (2015) Pauline Bros et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- ADAMTS expression and function in central nervous system injury and disorders
- (2015) Paul E. Gottschall et al. MATRIX BIOLOGY
- Cell type– and brain region–resolved mouse brain proteome
- (2015) Kirti Sharma et al. NATURE NEUROSCIENCE
- Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides
- (2015) Timo Jan Oberstein et al. NEUROBIOLOGY OF DISEASE
- Brain Amyloid-Beta Fragment Signatures in Pathological Ageing and Alzheimer's Disease by Hybrid Immunoprecipitation Mass Spectrometry
- (2015) Erik Portelius et al. Neurodegenerative Diseases
- The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family
- (2015) Richard Kelwick et al. GENOME BIOLOGY
- Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer’s disease
- (2014) Thomas A. Bayer et al. ACTA NEUROPATHOLOGICA
- The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes
- (2014) Hoang S. Nhan et al. ACTA NEUROPATHOLOGICA
- Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4)
- (2014) Kazuhiro Yamamoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cell-specific and developmental expression of lectican-cleaving proteases in mouse hippocampus and neocortex
- (2014) C. Levy et al. JOURNAL OF COMPARATIVE NEUROLOGY
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Differential Release of -Amyloid from Dendrite- Versus Axon-Targeted APP
- (2014) S. R. DeBoer et al. JOURNAL OF NEUROSCIENCE
- Truncated and modified amyloid-beta species
- (2014) Markus P Kummer et al. Alzheimers Research & Therapy
- N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits
- (2013) Yvonne Bouter et al. ACTA NEUROPATHOLOGICA
- Neurofibrillary tangles and plaques are not accompanied by white matter pathology in aged triple transgenic-Alzheimer disease mice
- (2013) Marzena Z. Kastyak-Ibrahim et al. MAGNETIC RESONANCE IMAGING
- Alzheimer’s disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production
- (2013) Mitko Dimitrov et al. Nature Communications
- N-truncated Abeta starting with position four: early intraneuronal accumulation and rescue of toxicity using NT4X-167, a novel monoclonal antibody
- (2013) Gregory Antonios et al. Acta Neuropathologica Communications
- Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator (tPA), ADAMTS-4, ADAMTS-5, and Their Modulators
- (2012) Dimitrije Krstic et al. PLoS One
- Overlapping profiles of Abeta peptides in the Alzheimer's disease and pathological aging brains
- (2012) Brenda D Moore et al. Alzheimers Research & Therapy
- Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragmentsin Vivo
- (2011) Tamara Jefferson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease
- (2011) Randall J Bateman et al. Alzheimers Research & Therapy
- Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer’s disease
- (2010) Erik Portelius et al. ACTA NEUROPATHOLOGICA
- Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target
- (2010) Maya K. Desai et al. AMERICAN JOURNAL OF PATHOLOGY
- Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer’s disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure
- (2010) Stefanie Hahn et al. JOURNAL OF NEUROCHEMISTRY
- The benefits and limitations of animal models for translational research in neurodegenerative diseases
- (2010) Mathias Jucker NATURE MEDICINE
- The secretases: enzymes with therapeutic potential in Alzheimer disease
- (2010) Bart De Strooper et al. Nature Reviews Neurology
- A Review of the ADAMTS Family, Pharmaceutical Targets of the Future
- (2009) Micky Tortorella et al. CURRENT PHARMACEUTICAL DESIGN
- A Disintegrin-like and Metalloprotease (Reprolysin-type) with Thrombospondin Type 1 Motif (ADAMTS) Superfamily: Functions and Mechanisms
- (2009) Suneel S. Apte JOURNAL OF BIOLOGICAL CHEMISTRY
- Oligodendrocytes are a Novel Source of Amyloid Peptide Generation
- (2009) Stephen D. Skaper et al. NEUROCHEMICAL RESEARCH
- Function, regulation and therapeutic properties of β-secretase (BACE1)
- (2009) Michael Willem et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Neprilysin and Amyloid Beta Peptide Degradation
- (2008) Louis Hersh et al. Current Alzheimer Research
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started