Prickle1 stunts limb growth through alteration of cell polarity and gene expression

Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis

(2013) Chunqiao Liu et al.   HUMAN MOLECULAR GENETICS

A balance of form and function: Planar polarity and development of the vestibular maculae

(2013) Michael R. Deans   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Somitogenesis

(2012) M. Maroto et al.   DEVELOPMENT

The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled

(2012) Derrick M. Glasco et al.   DEVELOPMENTAL BIOLOGY

Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis

(2012) Hirotaka Tao et al.   DEVELOPMENTAL BIOLOGY

The Wnt Coreceptor Ryk Regulates Wnt/Planar Cell Polarity by Modulating the Degradation of the Core Planar Cell Polarity Component Vangl2

(2012) Philipp Andre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Wnt Planar cell polarity (PCP) signaling promotes growth plate column formation in vitro

(2012) Rachel M. Randall et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Comparison of Phenotypes between Different vangl2 Mutants Demonstrates Dominant Effects of the Looptail Mutation during Hair Cell Development

(2012) Haifeng Yin et al.   PLoS One

Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism

(2012) R. Sheth et al.   SCIENCE

Mutations in Prickle Orthologs Cause Seizures in Flies, Mice, and Humans

(2011) Hirotaka Tao et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity

(2011) O. M. Mapp et al.   DEVELOPMENT

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

(2011) Bo Gao et al.   DEVELOPMENTAL CELL

Identification and characterization of novel rare mutations in the planar cell polarity genePRICKLE1in human neural tube defects

(2011) Ciprian M. Bosoi et al.   HUMAN MUTATION

Contribution of VANGL2 mutations to isolated neural tube defects

(2010) Z Kibar et al.   CLINICAL GENETICS

Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B

(2010) Bing Wang et al.   HUMAN MOLECULAR GENETICS

When pathways collide: collaboration and connivance among signalling proteins in development

(2010) Helen McNeill et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

VANGL2Mutations in Human Cranial Neural-Tube Defects

(2010) Yun-Ping Lei et al.   NEW ENGLAND JOURNAL OF MEDICINE

Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region

(2010) F. Witte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases

(2009) Masahiro Narimatsu et al.   CELL

Noncanonical frizzled signaling regulates cell polarity of growth plate chondrocytes

(2009) Y. Li et al.   DEVELOPMENT

Fgf-Dependent Etv4/5 Activity Is Required for Posterior Restriction of Sonic hedgehog and Promoting Outgrowth of the Vertebrate Limb

(2009) Junhao Mao et al.   DEVELOPMENTAL CELL

Deep homology and the origins of evolutionary novelty

(2009) Neil Shubin et al.   NATURE

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity

(2009) H. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Self-Regulatory System of Interlinked Signaling Feedback Loops Controls Mouse Limb Patterning

(2009) J.-D. Benazet et al.   SCIENCE

A Homozygous Mutation in Human PRICKLE1 Causes an Autosomal-Recessive Progressive Myoclonus Epilepsy-Ataxia Syndrome

(2008) Alexander G. Bassuk et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Expression of avianprickle genes during early development and organogenesis

(2008) Oliver Cooper et al.   DEVELOPMENTAL DYNAMICS

Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways

(2008) Albert Goldbeter et al.   JOURNAL OF THEORETICAL BIOLOGY

LIM domain protein TES changes its conformational states in different cellular compartments

(2008) Yingli Zhong et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

From individual Wnt pathways towards a Wnt signalling network

(2008) H. A Kestler et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES