The Many Faces of Neuroendocrine Differentiation in Prostate Cancer Progression

Concurrent AURKA and MYCN Gene Amplifications Are Harbingers of Lethal TreatmentRelated Neuroendocrine Prostate Cancer

(2015) Juan Miguel Mosquera et al.   NEOPLASIA

Cross Modulation between the Androgen Receptor Axis and Protocadherin-PC in Mediating Neuroendocrine Transdifferentiation and Therapeutic Resistance of Prostate Cancer

(2015) Stéphane Terry et al.   NEOPLASIA

The protocadherin 11X/Y (PCDH11X/Y) gene pair as determinant of cerebral asymmetry in modernHomo sapiens

(2013) Thomas H. Priddle et al.   Annals of the New York Academy of Sciences

Evolving landscape and novel treatments in metastatic castrate-resistant prostate cancer

(2013) Paul J Toren et al.   ASIAN JOURNAL OF ANDROLOGY

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Platinum-Based Chemotherapy for Variant Castrate-Resistant Prostate Cancer

(2013) A. M. Aparicio et al.   CLINICAL CANCER RESEARCH

Rb Loss Is Characteristic of Prostatic Small Cell Neuroendocrine Carcinoma

(2013) H.-L. Tan et al.   CLINICAL CANCER RESEARCH

Down-regulation of RE-1 silencing transcription factor (REST) in advanced prostate cancer by hypoxia-induced miR-106b~25

(2013) Hongzi Liang et al.   EXPERIMENTAL CELL RESEARCH

Y-chromosome evolution: emerging insights into processes of Y-chromosome degeneration

(2013) Doris Bachtrog   NATURE REVIEWS GENETICS

REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer

(2013) C. Svensson et al.   NUCLEIC ACIDS RESEARCH

Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches

(2013) T Karantanos et al.   ONCOGENE

Chromogranin a staining as a prognostic variable in newly diagnosed Gleason score 7-10 prostate cancer treated with definitive radiotherapy

(2013) Daniel J. Krauss et al.   PROSTATE

Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells

(2013) M. A. Nieto   SCIENCE

Rationale for Stereotactic Body Radiation Therapy in Treating Patients with Oligometastatic Hormone-Naïve Prostate Cancer

(2013) Onita Bhattasali et al.   Frontiers in Oncology

Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity

(2012) Himisha Beltran et al.   EUROPEAN UROLOGY

Ubiquitination and deubiquitination of REST and its roles in cancers

(2012) Zhi Huang et al.   FEBS LETTERS

Challenges in Recognizing Treatment-Related Neuroendocrine Prostate Cancer

(2012) Himisha Beltran et al.   JOURNAL OF CLINICAL ONCOLOGY

Wnt Signaling in Vertebrate Neural Development and Function

(2012) Kimberly A. Mulligan et al.   Journal of Neuroimmune Pharmacology

Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer

(2012) Chunxiao Wu et al.   JOURNAL OF PATHOLOGY

From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer

(2012) Anna V Lapuk et al.   JOURNAL OF PATHOLOGY

Midkine is associated with neuroendocrine differentiation in castration-resistant prostate cancer

(2012) Anna Nordin et al.   PROSTATE

Small cell carcinoma of the prostate after high-dose-rate brachytherapy for low-risk prostatic adenocarcinoma

(2012) AKIRA KOMIYA et al.   Oncology Letters

Survival of patients with small cell carcinoma of the prostate during 1973-2003: a population-based study

(2011) Sundeep Deorah et al.   BJU INTERNATIONAL

Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer

(2011) Brett S. Carver et al.   CANCER CELL

Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells

(2011) Mengqian Chen et al.   CELL CYCLE

Modeling a Lethal Prostate Cancer Variant with Small-Cell Carcinoma Features

(2011) V. Tzelepi et al.   CLINICAL CANCER RESEARCH

Histological variants of prostatic carcinoma and their significance

(2011) Peter A Humphrey   HISTOPATHOLOGY

Prognostic Significance of Neuroendocrine Differentiation in Patients With Gleason Score 8–10 Prostate Cancer Treated With Primary Radiotherapy

(2011) Daniel J. Krauss et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

ERG gene rearrangements are common in prostatic small cell carcinomas

(2011) Tamara L Lotan et al.   MODERN PATHOLOGY

Notch Signaling Modulates Hypoxia-Induced Neuroendocrine Differentiation of Human Prostate Cancer Cells

(2011) G. Danza et al.   MOLECULAR CANCER RESEARCH

A crucial requirement for Hedgehog signaling in small cell lung cancer

(2011) Kwon-Sik Park et al.   NATURE MEDICINE

Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets

(2011) H. Beltran et al.   Cancer Discovery

Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors

(2010) Jianfei Qi et al.   CANCER CELL

Class III  -Tubulin Expression Predicts Prostate Tumor Aggressiveness and Patient Response to Docetaxel-Based Chemotherapy

(2010) G. Ploussard et al.   CANCER RESEARCH

The transcriptional repressor REST/NRSF modulates hedgehog signaling

(2010) Keith P. Gates et al.   DEVELOPMENTAL BIOLOGY

Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells

(2010) Mengqian Chen et al.   Molecular Cancer

Wnt-11 promotes neuroendocrine-like differentiation, survival and migration of prostate cancer cells

(2010) Pinar Uysal-Onganer et al.   Molecular Cancer

Treatment strategies for high-risk locally advanced prostate cancer

(2010) Seth A. Rosenthal et al.   Nature Reviews Urology

Regulation of protocadherin gene expression by multiple neuron-restrictive silencer elements scattered in the gene cluster

(2010) Yuen-Peng Tan et al.   NUCLEIC ACIDS RESEARCH

Wnt/β-Catenin activation promotes prostate tumor progression in a mouse model

(2010) X Yu et al.   ONCOGENE

Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma

(2010) J Wang et al.   ONCOGENE

The Pathologic Classification of Neuroendocrine Tumors

(2010) David S. Klimstra et al.   PANCREAS

The epidemiology and survival of extrapulmonary small cell carcinoma in South East England, 1970–2004

(2009) Yien Ning S Wong et al.   BMC CANCER

Increased expression of class III β-tubulin in castration-resistant human prostate cancer

(2009) S Terry et al.   BRITISH JOURNAL OF CANCER

Stabilization of N-Myc Is a Critical Function of Aurora A in Human Neuroblastoma

(2009) Tobias Otto et al.   CANCER CELL

Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer

(2009) Chunru Lin et al.   CELL

WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics

(2009) Isabelle Bisson et al.   CELL RESEARCH

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo

(2009) Sebastian J. Arnold et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SharedTP53gene mutation in morphologically and phenotypically distinct concurrent primary small cell neuroendocrine carcinoma and adenocarcinoma of the prostate

(2009) Donna E. Hansel et al.   PROSTATE

Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

(2009) R.-S. Mani et al.   SCIENCE

Ionizing Radiation Induces Prostate Cancer Neuroendocrine Differentiation through Interplay of CREB and ATF2: Implications for Disease Progression

(2008) X. Deng et al.   CANCER RESEARCH

Comparative expression of Hedgehog ligands at different stages of prostate carcinoma progression

(2008) S Azoulay et al.   JOURNAL OF PATHOLOGY

Differential effects of prostate cancer therapeutics on neuroendocrine transdifferentiation

(2008) D. E. Frigo et al.   MOLECULAR CANCER THERAPEUTICS

Activation of β-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration

(2008) Xiuping Yu et al.   PROSTATE