Ubiquitination and deubiquitination of REST and its roles in cancers

REST Regulates Oncogenic Properties of Glioblastoma Stem Cells

(2012) Mohamed M. Kamal et al.   STEM CELLS

Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCFβ-TRCP in neuroblastoma cells

(2011) Akanksha Singh et al.   CANCER

Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3

(2011) Olga A. Guryanova et al.   CANCER CELL

Genetic ablation of a candidate tumor suppressor gene, Rest, does not promote mouse colon carcinogenesis

(2011) Yuichiro Hatano et al.   CANCER SCIENCE

Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells

(2011) Zhi Huang et al.   NATURE CELL BIOLOGY

Persistent Sonic Hedgehog Signaling in Adult Brain Determines Neural Stem Cell Positional Identity

(2011) Rebecca A. Ihrie et al.   NEURON

The transcriptional repressor REST/NRSF modulates hedgehog signaling

(2010) Keith P. Gates et al.   DEVELOPMENTAL BIOLOGY

BMP-induced REST regulates the establishment and maintenance of astrocytic identity

(2010) Jun Kohyama et al.   JOURNAL OF CELL BIOLOGY

Expression and functions of the repressor element 1 (RE-1)-silencing transcription factor (REST) in breast cancer

(2010) Hui Lv et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Notch signaling is not essential in sonic hedgehog-activated medulloblastoma

(2010) B A Hatton et al.   ONCOGENE

Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer

(2010) A Kreisler et al.   ONCOGENE

The Transcription Factor REST Is Lost in Aggressive Breast Cancer

(2010) Matthew P. Wagoner et al.   PLoS Genetics

Cancer stem cells in glioblastoma—molecular signaling and therapeutic targeting

(2010) Zhi Huang et al.   Protein & Cell

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

(2009) A. W. Bruce et al.   GENOME RESEARCH

Deletion of Atoh1 Disrupts Sonic Hedgehog Signaling in the Developing Cerebellum and Prevents Medulloblastoma

(2009) A. Flora et al.   SCIENCE

Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

(2009) R. L. Yauch et al.   SCIENCE

Squelching glioblastoma stem cells by targeting REST for proteasomal degradation

(2009) Peisu Zhang et al.   TRENDS IN NEUROSCIENCES

Profiling RE1/REST-mediated histone modifications in the human genome

(2009) Deyou Zheng et al.   GENOME BIOLOGY

SCG3 Transcript in Peripheral Blood Is a Prognostic Biomarker for REST-Deficient Small Cell Lung Cancer

(2008) A. C. Moss et al.   CLINICAL CANCER RESEARCH

Nontelomeric TRF2-REST Interaction Modulates Neuronal Gene Silencing and Fate of Tumor and Stem Cells

(2008) Peisu Zhang et al.   CURRENT BIOLOGY

CDYL Bridges REST and Histone Methyltransferases for Gene Repression and Suppression of Cellular Transformation

(2008) Peter Mulligan et al.   MOLECULAR CELL

REST maintains self-renewal and pluripotency of embryonic stem cells

(2008) Sanjay K. Singh et al.   NATURE

SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation

(2008) Thomas F. Westbrook et al.   NATURE

Control of chromosome stability by the β-TrCP–REST–Mad2 axis

(2008) Daniele Guardavaccaro et al.   NATURE