IGF2 increases de novo steroidogenesis in prostate cancer cells

Differences in phenotype and gene expression of prostate stromal cells from patients of varying ages and their influence on tumour formation by prostate epithelial cells

(2011) Yong-Chuan Wang et al.   ASIAN JOURNAL OF ANDROLOGY

The antiandrogenic effect of finasteride against a mutant androgen receptor

(2011) Yue Wu et al.   CANCER BIOLOGY & THERAPY

Serum insulin-like growth factors and mortality in localised and advanced clinically detected prostate cancer

(2011) Mari-Anne Rowlands et al.   CANCER CAUSES & CONTROL

Insulin Increases De Novo Steroidogenesis in Prostate Cancer Cells

(2011) A. A. Lubik et al.   CANCER RESEARCH

New Strategies in Metastatic Prostate Cancer: Targeting the Androgen Receptor Signaling Pathway

(2011) G. Attard et al.   CLINICAL CANCER RESEARCH

Insulin-like growth factor-2 (IGF2) loss of imprinting marks a field defect within human prostates containing cancer

(2011) Sachin Bhusari et al.   PROSTATE

Differential Mechanisms of Acquired Resistance to Insulin-like Growth Factor-I Receptor Antibody Therapy or to a Small-Molecule Inhibitor, BMS-754807, in a Human Rhabdomyosarcoma Model

(2010) F. Huang et al.   CANCER RESEARCH

Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy

(2010) D. B. Ulanet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer

(2010) Karen E. Knudsen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Aberrant epigenetic modifications in the CTCF binding domain of the IGF2/H19 gene in prostate cancer compared with benign prostate hyperplasia

(2009) Paradowska   INTERNATIONAL JOURNAL OF ONCOLOGY

Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts

(2009) Jennifer A. Locke et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR

(2009) J. M. Carboni et al.   MOLECULAR CANCER THERAPEUTICS

Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

(2009) A Gualberto et al.   ONCOGENE

Insulin, insulin-like growth factors and neoplasia

(2008) Michael Pollak   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

A novel high-affinity peptide antagonist to the insulin receptor

(2008) Lauge Schäffer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer

(2008) J. A. Locke et al.   CANCER RESEARCH

Targeting insulin and insulin-like growth factor signalling in oncology

(2008) Michael Pollak   CURRENT OPINION IN PHARMACOLOGY

Circulating insulin-like growth factor peptides and prostate cancer risk: A systematic review and meta-analysis

(2008) Mari-Anne Rowlands et al.   INTERNATIONAL JOURNAL OF CANCER

Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone Acetate, Confirms That Castration-Resistant Prostate Cancer Commonly Remains Hormone Driven

(2008) Gerhardt Attard et al.   JOURNAL OF CLINICAL ONCOLOGY

Insulin receptor expression by human prostate cancers

(2008) Michael E. Cox et al.   PROSTATE