The role of endogenous molecules in modulating pain through transient receptor potential vanilloid 1 (TRPV1)

TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids

(2013) Erhu Cao et al.   NEURON

Single Residues in the Outer Pore of TRPV1 and TRPV3 Have Temperature-Dependent Conformations

(2013) Sung Eun Kim et al.   PLoS One

Structure and Regulation of Soluble Guanylate Cyclase

(2012) Emily R. Derbyshire et al.   Annual Review of Biochemistry

Current progress in non-Edg family LPA receptor research

(2012) Keisuke Yanagida et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lysophosphatidic acid: Chemical signature of neuropathic pain

(2012) Hiroshi Ueda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Divalent Heavy Metal Cations Block the TRPV1 Ca2+ Channel

(2012) László Pecze et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons

(2012) Luciano De Petrocellis et al.   BRITISH JOURNAL OF PHARMACOLOGY

The functions of TRPA1 and TRPV1: moving away from sensory nerves

(2012) ES Fernandes et al.   BRITISH JOURNAL OF PHARMACOLOGY

The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms

(2012) Mohammad Alsalem et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting TRPV1 for pain relief: limits, losers and laurels

(2012) Arpad Szallasi et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

TRPV1-tubulin complex: involvement of membrane tubulin in the regulation of chemotherapy-induced peripheral neuropathy

(2012) Chandan Goswami   JOURNAL OF NEUROCHEMISTRY

Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors

(2012) A. M. Gregus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Omega-3 fatty acids and their lipid mediators: Towards an understanding of resolvin and protectin formation

(2012) Karsten H. Weylandt et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Multisteric TRPV1 nocisensor: a target for analgesics

(2012) János Szolcsányi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The thermo-TRP ion channel family: properties and therapeutic implications

(2011) Laura Vay et al.   BRITISH JOURNAL OF PHARMACOLOGY

The biophysical and molecular basis of TRPV1 proton gating

(2011) Eduardo Aneiros et al.   EMBO JOURNAL

Identification of a Binding Motif in the S5 Helix That Confers Cholesterol Sensitivity to the TRPV1 Ion Channel

(2011) Giovanni Picazo-Juárez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Localization of the PIP2 Sensor of TRPV1 Ion Channels

(2011) Carmen A. Ufret-Vincenty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resolvin D2 Is a Potent Endogenous Inhibitor for Transient Receptor Potential Subtype V1/A1, Inflammatory Pain, and Spinal Cord Synaptic Plasticity in Mice: Distinct Roles of Resolvin D1, D2, and E1

(2011) C.-K. Park et al.   JOURNAL OF NEUROSCIENCE

Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site

(2011) Andrés Nieto-Posadas et al.   Nature Chemical Biology

Transient receptor potential channels as therapeutic targets

(2011) Magdalene M. Moran et al.   NATURE REVIEWS DRUG DISCOVERY

The Human Serum Metabolome

(2011) Nikolaos Psychogios et al.   PLoS One

A thermodynamic framework for understanding temperature sensing by transient receptor potential (TRP) channels

(2011) D. E. Clapham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modular thermal sensors in temperature-gated transient receptor potential (TRP) channels

(2011) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transient receptor potential family of ion channels

(2011) Bernd Nilius et al.   GENOME BIOLOGY

Kinetic and Energetic Analysis of Thermally Activated TRPV1 Channels

(2010) Jing Yao et al.   BIOPHYSICAL JOURNAL

A “Cute” Desensitization of TRPV1

(2010) Filip Touska et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

TRPV1 Function in Health and Disease

(2010) John P.M. White et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Molecular basis of epithelial Ca2+and Mg2+transport: insights from the TRP channel family

(2010) Henrik Dimke et al.   JOURNAL OF PHYSIOLOGY-LONDON

Involvement of Lysophosphatidic Acid in Bone Cancer Pain by Potentiation of TRPV1 via PKCe Pathway in Dorsal Root Ganglion Neurons

(2010) Hai-Li Pan et al.   Molecular Pain

Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions

(2010) Zhen-Zhong Xu et al.   NATURE MEDICINE

TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus

(2010) Andrés E Chávez et al.   NATURE NEUROSCIENCE

Postsynaptic TRPV1 triggers cell type–specific long-term depression in the nucleus accumbens

(2010) Brad A Grueter et al.   NATURE NEUROSCIENCE

Pore turret of thermal TRP channels is not essential for temperature sensing

(2010) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thermosensitive TRP channel pore turret is part of the temperature activation pathway

(2010) F. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV1: On the Road to Pain Relief

(2010) Andres Jara-Oseguera et al.   Current Molecular Pharmacology

Divide and Conquer: High Resolution Structural Information on TRP Channel Fragments

(2009) Rachelle Gaudet   JOURNAL OF GENERAL PHYSIOLOGY

TRPV1 Is Activated by Both Acidic and Basic pH

(2009) A. Dhaka et al.   JOURNAL OF NEUROSCIENCE

Lipid bilayer regulation of membrane protein function: gramicidin channels as molecular force probes

(2009) J. A. Lundbaek et al.   Journal of the Royal Society Interface

Structural determinants of gating in the TRPV1 channel

(2009) Héctor Salazar et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia

(2009) A. M. Patwardhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor

(2008) P Holzer   BRITISH JOURNAL OF PHARMACOLOGY

ThermoTRP Channels in Nociceptors: Taking a Lead from Capsaicin Receptor TRPV1

(2008) Basil Roufogalis et al.   Current Neuropharmacology

Actions of 3-methyl-N-oleoyldopamine, 4-methyl-N-oleoyldopamine and N-oleoylethanolamide on the rat TRPV1 receptor in vitro and in vivo

(2008) Róbert Almási et al.   LIFE SCIENCES

Direct Activation of Transient Receptor Potential Vanilloid 1(TRPV1) by Diacylglycerol (DAG)

(2008) Dong Ho Woo et al.   Molecular Pain

Pore region of TRPV3 ion channel is specifically required for heat activation

(2008) Jörg Grandl et al.   NATURE NEUROSCIENCE

TRPV1 shows dynamic ionic selectivity during agonist stimulation

(2008) Man-Kyo Chung et al.   NATURE NEUROSCIENCE

Structure of TRPV1 channel revealed by electron cryomicroscopy

(2008) V. Y. Moiseenkova-Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA