Bacterial Effectors and Their Functions in the Ubiquitin-Proteasome System: Insight from the Modes of Substrate Recognition

Bacterial Serine/Threonine Protein Kinases in Host-Pathogen Interactions

(2014) Marc J. Canova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent changes in bacteremia in patients with cancer: a systematic review of epidemiology and antibiotic resistance

(2013) E. Montassier et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI

(2013) Akira Nishide et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase

(2013) A. F. A. Keszei et al.   MOLECULAR AND CELLULAR BIOLOGY

New antibiotics for bad bugs: where are we?

(2013) Matteo Bassetti et al.   Annals of Clinical Microbiology and Antimicrobials

The Inside Story of Shigella Invasion of Intestinal Epithelial Cells

(2013) N. Carayol et al.   Cold Spring Harbor Perspectives in Medicine

Shigella IpaH0722 E3 Ubiquitin Ligase Effector Targets TRAF2 to Inhibit PKC–NF-κB Activity in Invaded Epithelial Cells

(2013) Hiroshi Ashida et al.   PLoS Pathogens

Complex Structure of OspI and Ubc13: The Molecular Basis of Ubc13 Deamidation and Convergence of Bacterial and Host E2 Recognition

(2013) Panhan Fu et al.   PLoS Pathogens

The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity

(2013) Amit P. Bhavsar et al.   PLoS Pathogens

Shigella flexneriT3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-κB p65 protein

(2012) Fang Wang et al.   CELLULAR MICROBIOLOGY

Protein Export According to Schedule: Architecture, Assembly, and Regulation of Type III Secretion Systems from Plant- and Animal-Pathogenic Bacteria

(2012) D. Buttner   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response

(2012) Takahito Sanada et al.   NATURE

The molecular basis of ubiquitin-like protein NEDD8 deamidation by the bacterial effector protein Cif

(2012) A. Crow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis

(2012) Q. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diverse ubiquitin signaling in NF-κB activation

(2012) Kazuhiro Iwai   TRENDS IN CELL BIOLOGY

A bacterial effector targets the TRAF6-NFκB pathway to modulate the acute inflammatory response to bacterial invasion of epithelial cells

(2012) Takahito Sanada et al.   Virulence

Functional Analysis of NopM, a Novel E3 Ubiquitin Ligase (NEL) Domain Effector of Rhizobium sp. Strain NGR234

(2012) Da-Wei Xin et al.   PLoS Pathogens

Structural Analysis of Pseudomonas syringae AvrPtoB Bound to Host BAK1 Reveals Two Similar Kinase-Interacting Domains in a Type III Effector

(2011) Wei Cheng et al.   Cell Host & Microbe

Subcellular Targeting of Salmonella Virulence Proteins by Host-Mediated S-Palmitoylation

(2011) Stuart W. Hicks et al.   Cell Host & Microbe

Enteropathogenic Escherichia coli infection in children

(2011) Theresa J. Ochoa et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Conserved Structural Mechanisms for Autoinhibition in IpaH Ubiquitin Ligases

(2011) Yang-Chieh Chou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation

(2011) Li Zhang et al.   NATURE

The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation

(2011) Allan M. Weissman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The EHEC Type III Effector NleL Is an E3 Ubiquitin Ligase That Modulates Pedestal Formation

(2011) Heather Piscatelli et al.   PLoS One

Cycle Inhibiting Factors (Cifs): Cyclomodulins That Usurp the Ubiquitin-Dependent Degradation Pathway of Host Cells

(2011) Frédéric Taieb et al.   Toxins

The bacterial effector Cif interferes with SCF ubiquitin ligase function by inhibiting deneddylation of Cullin1

(2010) Hanako Morikawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Will the Ubiquitin System Furnish as Many Drug Targets as Protein Kinases?

(2010) Philip Cohen et al.   CELL

Pathogen-Mediated Posttranslational Modifications: A Re-emerging Field

(2010) David Ribet et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Bacterial Interactions with the Host Epithelium

(2010) Minsoo Kim et al.   Cell Host & Microbe

Destabilization of YopE by the Ubiquitin-Proteasome Pathway Fine-Tunes Yop Delivery into Host Cells and Facilitates Systemic Spread ofYersinia enterocoliticain Host Lymphoid Tissue

(2010) Kristin Gaus et al.   INFECTION AND IMMUNITY

Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase fromEscherichia coliO157:H7

(2010) David Yin-wei Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TheSalmonellaType III Secretion Effector,SalmonellaLeucine-rich Repeat Protein (SlrP), Targets the Human Chaperone ERdj3

(2010) Joaquín Bernal-Bayard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamine Deamidation and Dysfunction of Ubiquitin/NEDD8 Induced by a Bacterial Effector Family

(2010) J. Cui et al.   SCIENCE

NleG Type 3 Effectors from Enterohaemorrhagic Escherichia coli Are U-Box E3 Ubiquitin Ligases

(2010) Bin Wu et al.   PLoS Pathogens

Pathogenic Bacteria Target NEDD8-Conjugated Cullins to Hijack Host-Cell Signaling Pathways

(2010) Grégory Jubelin et al.   PLoS Pathogens

Legionella Metaeffector Exploits Host Proteasome to Temporally Regulate Cognate Effector

(2010) Tomoko Kubori et al.   PLoS Pathogens

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Diversification of a Salmonella Virulence Protein Function by Ubiquitin-Dependent Differential Localization

(2009) Jayesh C. Patel et al.   CELL

Ubiquitination, Ubiquitin-like Modifiers, and Deubiquitination in Viral Infection

(2009) Marisa K. Isaacson et al.   Cell Host & Microbe

Ubiquitination of the bacterial inositol phosphatase, SopB, regulates its biological activity at the plasma membrane

(2009) Leigh A. Knodler et al.   CELLULAR MICROBIOLOGY

AvrPtoB Targets the LysM Receptor Kinase CERK1 to Promote Bacterial Virulence on Plants

(2009) Selena Gimenez-Ibanez et al.   CURRENT BIOLOGY

Hijacking the host ubiquitin pathway: structural strategies of bacterial E3 ubiquitin ligases

(2009) Stuart W Hicks et al.   CURRENT OPINION IN MICROBIOLOGY

The Enteropathogenic Escherichia coli Effector Cif Induces Delayed Apoptosis in Epithelial Cells

(2009) A. Samba-Louaka et al.   INFECTION AND IMMUNITY

SalmonellaType III Secretion Effector SlrP Is an E3 Ubiquitin Ligase for Mammalian Thioredoxin

(2009) Joaquín Bernal-Bayard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enterohaemorrhagic Escherichia coli serogroup O111 inhibits NF- B-dependent innate responses in a manner independent of a type III secreted OspG orthologue

(2009) R. Nobe et al.   MICROBIOLOGY-SGM

Advances in experimental methods for the elucidation ofPseudomonas syringaeeffector function with a focus on AvrPtoB

(2009) KATHY R. MUNKVOLD et al.   MOLECULAR PLANT PATHOLOGY

Ubiquitylation in innate and adaptive immunity

(2009) Vijay G. Bhoj et al.   NATURE

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response

(2009) Hiroshi Ashida et al.   NATURE CELL BIOLOGY

Crystal Structures of Cif from Bacterial Pathogens Photorhabdus luminescens and Burkholderia pseudomallei

(2009) Allister Crow et al.   PLoS One

A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle

(2009) Q. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases

(2009) C. M. Quezada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plant Pattern-Recognition Receptor FLS2 Is Directed for Degradation by the Bacterial Ubiquitin Ligase AvrPtoB

(2008) Vera Göhre et al.   CURRENT BIOLOGY

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Structure of the Cyclomodulin Cif from Pathogenic Escherichia coli

(2008) Yun Hsu et al.   JOURNAL OF MOLECULAR BIOLOGY

Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions

(2008) Tomoko Kubori et al.   MOLECULAR MICROBIOLOGY

Structure of a Shigella effector reveals a new class of ubiquitin ligases

(2008) Yongqun Zhu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

(2008) Alexander U Singer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY