Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis

The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response

(2012) Takahito Sanada et al.   NATURE

NEDD8 Pathways in Cancer, Sine Quibus Non

(2011) Ian R. Watson et al.   CANCER CELL

Crystal Structures of Protein Glutaminase and Its Pro Forms Converted into Enzyme-Substrate Complex

(2011) Ryota Hashizume et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Burkholderia pseudomallei Toxin Inhibits Helicase Activity of Translation Factor eIF4A

(2011) A. Cruz-Migoni et al.   SCIENCE

Biochemistry and cell signaling taught by bacterial effectors

(2011) Jixin Cui et al.   TRENDS IN BIOCHEMICAL SCIENCES

The bacterial effector Cif interferes with SCF ubiquitin ligase function by inhibiting deneddylation of Cullin1

(2010) Hanako Morikawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metalloprotease type III effectors that specifically cleave JNK and NF-κB

(2010) Kobi Baruch et al.   EMBO JOURNAL

The NMR structure of protein-glutaminase from Chryseobacterium proteolyticum

(2010) Hiroyuki Kumeta et al.   JOURNAL OF BIOMOLECULAR NMR

Glutamine Deamidation and Dysfunction of Ubiquitin/NEDD8 Induced by a Bacterial Effector Family

(2010) J. Cui et al.   SCIENCE

Pathogenic Bacteria Target NEDD8-Conjugated Cullins to Hijack Host-Cell Signaling Pathways

(2010) Grégory Jubelin et al.   PLoS Pathogens

Glutamine-Specific N-Terminal Amidase, a Component of the N-End Rule Pathway

(2009) Haiqing Wang et al.   MOLECULAR CELL

Ubiquitin-binding domains — from structures to functions

(2009) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crystal Structures of Cif from Bacterial Pathogens Photorhabdus luminescens and Burkholderia pseudomallei

(2009) Allister Crow et al.   PLoS One

A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle

(2009) Q. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pasteurella multocida toxin activation of heterotrimeric G proteins by deamidation

(2009) J. H. C. Orth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insights into E1-Catalyzed Ubiquitin Activation and Transfer to Conjugating Enzymes

(2008) Imsang Lee et al.   CELL

Function and regulation of protein neddylation. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Gwénaël Rabut et al.   EMBO REPORTS

Structure of the Cyclomodulin Cif from Pathogenic Escherichia coli

(2008) Yun Hsu et al.   JOURNAL OF MOLECULAR BIOLOGY