Pharmacotherapy for obesity: novel agents and paradigms

The clinical effectiveness and cost-effectiveness of long-term weight management schemes for adults: a systematic review

(2014) E Loveman et al.   HEALTH TECHNOLOGY ASSESSMENT

The Long-term Effectiveness of a Lifestyle Intervention in Severely Obese Individuals

(2013) Jessica L. Unick et al.   AMERICAN JOURNAL OF MEDICINE

Feasibility and indicative results from a 12-month low-energy liquid diet treatment and maintenance programme for severe obesity

(2013) Michael Lean et al.   BRITISH JOURNAL OF GENERAL PRACTICE

Echocardiographic Assessment of Cardiac Valvular Regurgitation With Lorcaserin From Analysis of 3 Phase 3 Clinical Trials

(2013) Neil J. Weissman et al.   Circulation-Cardiovascular Imaging

Action on obesity: comprehensive care for all

(2013) J. Wass et al.   CLINICAL MEDICINE

Pharmacologic Treatment Options for Obesity: What Is Old Is New Again

(2013) Donna H. Ryan et al.   CURRENT HYPERTENSION REPORTS

Benefits of Liraglutide Treatment in Overweight and Obese Older Individuals With Prediabetes

(2013) S. H. Kim et al.   DIABETES CARE

Metabolic Effects of Bariatric Surgery in Patients With Moderate Obesity and Type 2 Diabetes: Analysis of a randomized control trial comparing surgery with intensive medical treatment

(2013) S. R. Kashyap et al.   DIABETES CARE

A Critical Analysis of the Clinical Use of Incretin-Based Therapies: Are the GLP-1 therapies safe?

(2013) P. C. Butler et al.   DIABETES CARE

Obesity in Europe – does anybody care?

(2013) Arne Astrup et al.   EXPERT OPINION ON PHARMACOTHERAPY

Incretin hormones and the satiation signal

(2013) J J Holst   INTERNATIONAL JOURNAL OF OBESITY

Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: The SCALE Maintenance randomized study

(2013) T A Wadden et al.   INTERNATIONAL JOURNAL OF OBESITY

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

(2013) Sonja I Berndt et al.   NATURE GENETICS

Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity

(2013) Eleanor Wheeler et al.   NATURE GENETICS

From obesity genetics to the future of personalized obesity therapy

(2013) Julia S. El-Sayed Moustafa et al.   Nature Reviews Endocrinology

Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Weight control practices of severely obese patients who are not seeking bariatric surgery

(2013) David Arterburn et al.   Obesity

Why do we need drugs to treat the patient with obesity?

(2013) George A. Bray   Obesity

The disproportionate economic burden associated with severe and complicated obesity: a systematic review

(2013) E. Grieve et al.   Obesity Reviews

Efficacy and safety of lorcaserin in obese adults: a meta-analysis of 1-year randomized controlled trials (RCTs) and narrative review on short-term RCTs

(2013) E. W. Chan et al.   Obesity Reviews

Weight Recidivism Post-Bariatric Surgery: A Systematic Review

(2013) Shahzeer Karmali et al.   OBESITY SURGERY

Contribution of 32 GWAS-Identified Common Variants to Severe Obesity in European Adults Referred for Bariatric Surgery

(2013) Reedik Mägi et al.   PLoS One

Has pancreatic damage from glucagon suppressing diabetes drugs been underplayed?

(2013) D. Cohen   BMJ-British Medical Journal

Expectations for Weight Loss and Willingness to Accept Risk Among Patients Seeking Weight Loss Surgery

(2013) Christina C. Wee et al.   JAMA Surgery

Topiramate: Effects on cognition in patients with epilepsy, migraine headache and obesity

(2013) Barbara R. Sommer et al.   Therapeutic Advances in Neurological Disorders

Effectiveness of interventions for reducing diabetes and cardiovascular disease risk in people with metabolic syndrome: systematic review and mixed treatment comparison meta-analysis

(2012) A. J. Dunkley et al.   DIABETES OBESITY & METABOLISM

Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes

(2012) Michael Horowitz et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Anti-obesity drugs: past, present and future

(2012) R. J. Rodgers et al.   Disease Models & Mechanisms

Cardiovascular Biology of the Incretin System

(2012) John R. Ussher et al.   ENDOCRINE REVIEWS

Bariatric Surgery and Long-term Cardiovascular Events

(2012) Lars Sjöström et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prevalence of Obesity and Trends in the Distribution of Body Mass Index Among US Adults, 1999-2010

(2012) Katherine M. Flegal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Randomized Placebo-Controlled Clinical Trial of Lorcaserin for Weight Loss in Type 2 Diabetes Mellitus: The BLOOM-DM Study

(2012) Patrick M. O'Neil et al.   Obesity

Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study

(2011) W Timothy Garvey et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

First Report from the American College of Surgeons Bariatric Surgery Center Network

(2011) Matthew M. Hutter et al.   ANNALS OF SURGERY

Maintained intentional weight loss reduces cardiovascular outcomes: results from the Sibutramine Cardiovascular OUTcomes (SCOUT) trial

(2011) I. D. Caterson et al.   DIABETES OBESITY & METABOLISM

Adherence to weight loss medications; post-marketing study from HMO pharmacy data of one million individuals

(2011) Beatriz Hemo et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity

(2011) J. R. Speakman et al.   Disease Models & Mechanisms

Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide

(2011) A Astrup et al.   INTERNATIONAL JOURNAL OF OBESITY

A One-Year Randomized Trial of Lorcaserin for Weight Loss in Obese and Overweight Adults: The BLOSSOM Trial

(2011) Meredith C. Fidler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The global obesity pandemic: shaped by global drivers and local environments

(2011) Boyd A Swinburn et al.   LANCET

Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial

(2011) Kishore M Gadde et al.   LANCET

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

(2011) Mariel M Finucane et al.   LANCET

Controlled-Release Phentermine/Topiramate in Severely Obese Adults: A Randomized Controlled Trial (EQUIP)

(2011) David B. Allison et al.   Obesity

Ten years of leptin replacement therapy

(2011) G. Paz-Filho et al.   Obesity Reviews

Neuropsychiatric Adverse Effects of Centrally Acting Antiobesity Drugs

(2010) Pradeep J. Nathan et al.   CNS Neuroscience & Therapeutics

Metabolism and Excretion of the Once-Daily Human Glucagon-Like Peptide-1 Analog Liraglutide in Healthy Male Subjects and Its In Vitro Degradation by Dipeptidyl Peptidase IV and Neutral Endopeptidase

(2010) M. Malm-Erjefalt et al.   DRUG METABOLISM AND DISPOSITION

Genomics, Type 2 Diabetes, and Obesity

(2010) Mark I. McCarthy   NEW ENGLAND JOURNAL OF MEDICINE

Multicenter, Placebo-Controlled Trial of Lorcaserin for Weight Management

(2010) Steven R. Smith et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of Sibutramine on Cardiovascular Outcomes in Overweight and Obese Subjects

(2010) W. Philip T. James et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study

(2009) Arne Astrup et al.   LANCET

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

(2009) Prospective Studies Collaboration   LANCET

Incretin-based therapies for type 2 diabetes mellitus

(2009) Julie A. Lovshin et al.   Nature Reviews Endocrinology

Human Obesity: A Heritable Neurobehavioral Disorder That Is Highly Sensitive to Environmental Conditions

(2008) S. O'Rahilly et al.   DIABETES

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS