Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer

Dual Role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

(2014) Yongjie Wei et al.   Autophagy

Molecularly targeted therapies for metastatic triple-negative breast cancer

(2013) Soley Bayraktar et al.   BREAST CANCER RESEARCH AND TREATMENT

Analysis of pattern, time and risk factors influencing recurrence in triple-negative breast cancer patients

(2013) Katarzyna Pogoda et al.   MEDICAL ONCOLOGY

Targeting Basal-Like Breast Cancers

(2012) Nandini Dey et al.   CURRENT DRUG TARGETS

Parthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells

(2012) Antonella D'Anneo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis

(2011) Nan Zhang et al.   Autophagy

Discrimination between primary necrosis and apoptosis by necrostatin-1 in Annexin V-positive/propidium iodide-negative cells

(2011) Hirofumi Sawai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adjuvant systemic treatment for individual patients with triple negative breast cancer

(2011) Catherine Oakman et al.   BREAST

Protective effect of apocynin, a NADPH-oxidase inhibitor, against contrast-induced nephropathy in the diabetic rats: A comparison with n-acetylcysteine

(2011) Akbar Ahmad et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Parthenolide, a Sesquiterpene Lactone, Expresses Multiple Anti-cancer and Anti-inflammatory Activities

(2011) Vivek Bhakta Mathema et al.   INFLAMMATION

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

(2011) Maria Feoktistova et al.   MOLECULAR CELL

Triple-Negative Breast Cancer: An Unmet Medical Need

(2011) C. A. Hudis et al.   ONCOLOGIST

Current strategy for triple-negative breast cancer: appropriate combination of surgery, radiation, and chemotherapy

(2011) Hiroshi Yagata et al.   Breast Cancer

A NADPH Oxidase–Dependent Redox Signaling Pathway Mediates the Selective Radiosensitization Effect of Parthenolide in Prostate Cancer Cells

(2010) Yulan Sun et al.   CANCER RESEARCH

A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-κB and generating reactive oxygen species

(2010) Rajasubramaniam Shanmugam et al.   INTERNATIONAL JOURNAL OF CANCER

Parthenolide sensitizes hepatocellular carcinoma cells to trail by inducing the expression of death receptors through inhibition of STAT3 activation

(2010) Daniela Carlisi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Parthenolide induces proliferation inhibition and apoptosis of pancreatic cancer cells in vitro

(2010) Jun-Wei Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

(2010) E. J. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A water-soluble parthenolide analogue suppresses in vivo prostate cancer growth by targeting NFκB and generating reactive oxygen species

(2010) Rajasubramaniam Shanmugam et al.   PROSTATE

Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death

(2009) Kyung-Jin Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1α and P-glycoprotein overexpression

(2009) C Riganti et al.   BRITISH JOURNAL OF PHARMACOLOGY

RIP Kinases at the Crossroads of Cell Death and Survival

(2009) Wim Declercq et al.   CELL

Antimyeloma Effects of a Sesquiterpene Lactone Parthenolide

(2008) A. Suvannasankha et al.   CLINICAL CANCER RESEARCH

iNOS expression requires NADPH oxidase-dependent redox signaling in microvascular endothelial cells

(2008) Feng Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

3-Nitrofluoranthene (3-NF) but not 3-aminofluoranthene (3-AF) elicits apoptosis as well as programmed necrosis in Hepa1c1c7 cells

(2008) Nana Asare et al.   TOXICOLOGY