Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury

Matrix Metalloproteinase-8 Inhibition Prevents Disruption of Blood–Spinal Cord Barrier and Attenuates Inflammation in Rat Model of Spinal Cord Injury

(2017) Hemant Kumar et al.   MOLECULAR NEUROBIOLOGY

Propitious Therapeutic Modulators to Prevent Blood-Spinal Cord Barrier Disruption in Spinal Cord Injury

(2016) Hemant Kumar et al.   MOLECULAR NEUROBIOLOGY

Interleukin-6 Stimulates Defective Angiogenesis

(2015) G. Gopinathan et al.   CANCER RESEARCH

Diffuse and persistent blood–spinal cord barrier disruption after contusive spinal cord injury rapidly recovers following intravenous infusion of bone marrow mesenchymal stem cells

(2015) Takashi Matsushita et al.   EXPERIMENTAL NEUROLOGY

An efficient device to experimentally model compression injury of mammalian spinal cord

(2015) Alexander E. Ropper et al.   EXPERIMENTAL NEUROLOGY

Neutrophil elastase mediates acute pathogenesis and is a determinant of long-term behavioral recovery after traumatic injury to the immature brain

(2015) Bridgette D. Semple et al.   NEUROBIOLOGY OF DISEASE

Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

(2015) J. Ruschel et al.   SCIENCE

Neutrophils Mediate Blood–Spinal Cord Barrier Disruption in Demyelinating Neuroinflammatory Diseases

(2014) Benoit Aubé et al.   JOURNAL OF IMMUNOLOGY

Neutrophil contribution to spinal cord injury and repair

(2014) Virginie Neirinckx et al.   Journal of Neuroinflammation

A Simplified Up-Down Method (SUDO) for Measuring Mechanical Nociception in Rodents Using von Frey Filaments

(2014) Robert P Bonin et al.   Molecular Pain

Clinical utility of the neutrophil elastase inhibitor sivelestat for the treatment of acute respiratory distress syndrome

(2014) Yasushi Kawasaki et al.   Therapeutics and Clinical Risk Management

Neutrophil Elastase Inhibitor Sivelestat Attenuates Perioperative Inflammatory Response in Pediatric Heart Surgery With Cardiopulmonary Bypass

(2013) Nobuyuki Inoue et al.   International Heart Journal

Characterization of Vascular Disruption and Blood–Spinal Cord Barrier Permeability following Traumatic Spinal Cord Injury

(2013) Sarah A. Figley et al.   JOURNAL OF NEUROTRAUMA

Fluoxetine treatment promotes functional recovery in a rat model of cervical spinal cord injury

(2013) Manuela Scali et al.   Scientific Reports

Angiopoietins regulate vascular reactivity after haemorrhagic shock in rats through the Tie2-nitric oxide pathway

(2012) Jing Xu et al.   CARDIOVASCULAR RESEARCH

Traumatic Spinal Cord Injury Alters Angiogenic Factors and TGF-Beta1 that may Affect Vascular Recovery

(2012) Marie-Francoise Ritz et al.   CURRENT NEUROVASCULAR RESEARCH

Clinical evaluation of sivelestat for acute lung injury/acute respiratory distress syndrome following surgery for abdominal sepsis

(2012) Yoshiaki Tsuboko et al.   Drug Design Development and Therapy

Prevention of Both Neutrophil and Monocyte Recruitment Promotes Recovery after Spinal Cord Injury

(2011) Sang Mi Lee et al.   JOURNAL OF NEUROTRAUMA

Induction of angiopoietin-2 after spinal cord injury

(2011) J.C. Durham-Lee et al.   NEUROSCIENCE

Rescuing vasculature with intravenous angiopoietin-1 and  v 3 integrin peptide is protective after spinal cord injury

(2010) S. Han et al.   BRAIN

Angiopoietin-1 Induces Migration of Monocytes in a Tie-2 and Integrin-Independent Manner

(2010) Shakil Ahmad et al.   HYPERTENSION

Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema

(2010) Yuka Ikegame et al.   HYPERTENSION RESEARCH

Sustained Expression of Vascular Endothelial Growth Factor and Angiopoietin-1 Improves Blood–Spinal Cord Barrier Integrity and Functional Recovery after Spinal Cord Injury

(2010) Juan J. Herrera et al.   JOURNAL OF NEUROTRAUMA

The role of the Angiopoietins in vascular morphogenesis

(2009) Markus Thomas et al.   ANGIOGENESIS

Phosphorylation of endothelial nitric oxide synthase by atypical PKC  contributes to angiopoietin-1-dependent inhibition of VEGF-induced endothelial permeability in vitro

(2009) M. Oubaha et al.   BLOOD

Recovery from spinal cord injury: regeneration, plasticity and rehabilitation

(2009) J. W. Fawcett   BRAIN

Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface

(2009) Hye Shin Lee et al.   FEBS Journal

Protective effect of sivelestat sodium hydrate (ONO-5046) on ischemic spinal cord injury

(2009) S. Iwamoto et al.   Interactive Cardiovascular and Thoracic Surgery

Dexamethasone coordinately regulates angiopoietin-1 and VEGF: A mechanism of glucocorticoid-induced stabilization of blood–brain barrier

(2008) Hyongbum Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ectopic expression of angiopoietin-1 promotes neuronal differentiation in neural progenitor cells through the Akt pathway

(2008) Yun Bai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vascular Endothelial Growth Factor and Angiopoietins in Neurovascular Regeneration and Protection Following Stroke

(2008) Tania Hansen et al.   CURRENT NEUROVASCULAR RESEARCH

Transcriptomic Screening of Microvascular Endothelial Cells Implicates Novel Molecular Regulators of Vascular Dysfunction after Spinal Cord Injury

(2008) Richard L Benton et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Mechanisms and implications of adaptive immune responses after traumatic spinal cord injury

(2008) D.P. Ankeny et al.   NEUROSCIENCE