Matrix Metalloproteinase-8 Inhibition Prevents Disruption of Blood–Spinal Cord Barrier and Attenuates Inflammation in Rat Model of Spinal Cord Injury

Non-alcoholic fatty liver disease induces signs of Alzheimer’s disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD model

(2016) Do-Geun Kim et al.   Journal of Neuroinflammation

Propitious Therapeutic Modulators to Prevent Blood-Spinal Cord Barrier Disruption in Spinal Cord Injury

(2016) Hemant Kumar et al.   MOLECULAR NEUROBIOLOGY

Exploratory study to suggest the possibility of MMP-8 and MMP-9 serum levels as early markers for remission after traumatic spinal cord injury

(2016) A Moghaddam et al.   SPINAL CORD

An efficient device to experimentally model compression injury of mammalian spinal cord

(2015) Alexander E. Ropper et al.   EXPERIMENTAL NEUROLOGY

Ghrelin inhibits BSCB disruption/hemorrhage by attenuating MMP-9 and SUR1/TrpM4 expression and activation after spinal cord injury

(2014) Jee Y. Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neutrophils Mediate Blood–Spinal Cord Barrier Disruption in Demyelinating Neuroinflammatory Diseases

(2014) Benoit Aubé et al.   JOURNAL OF IMMUNOLOGY

Matrix Metalloproteinase-8 Plays a Pivotal Role in Neuroinflammation by Modulating TNF-α Activation

(2014) Eun-Jung Lee et al.   JOURNAL OF IMMUNOLOGY

Neutrophil contribution to spinal cord injury and repair

(2014) Virginie Neirinckx et al.   Journal of Neuroinflammation

Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice

(2014) E. A. Winkler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical utility of the neutrophil elastase inhibitor sivelestat for the treatment of acute respiratory distress syndrome

(2014) Yasushi Kawasaki et al.   Therapeutics and Clinical Risk Management

Matrix Metalloproteinase 8 (Collagenase 2) Induces the Expression of Interleukins 6 and 8 in Breast Cancer Cells

(2013) Sally Thirkettle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiplex array proteomics detects increased MMP-8 in CSF after spinal cord injury

(2012) Matthew Light et al.   Journal of Neuroinflammation

Matrix Metalloprotease 8-Dependent Extracellular Matrix Cleavage at the Blood-CSF Barrier Contributes to Lethality during Systemic Inflammatory Diseases

(2012) R. E. Vandenbroucke et al.   JOURNAL OF NEUROSCIENCE

Acute Molecular Perturbation of Inducible Nitric Oxide Synthase with an Antisense Approach Enhances Neuronal Preservation and Functional Recovery after Contusive Spinal Cord Injury

(2012) Dominic M. Maggio et al.   JOURNAL OF NEUROTRAUMA

TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells

(2011) Muhammad Aslam et al.   CYTOKINE

Matrix metalloproteinase8 has a central role in inflammatory disorders and cancer progression

(2011) Eline Dejonckheere et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Prevention of Both Neutrophil and Monocyte Recruitment Promotes Recovery after Spinal Cord Injury

(2011) Sang Mi Lee et al.   JOURNAL OF NEUROTRAUMA

Induction of Autophagy and Autophagic Cell Death in Damaged Neural Tissue After Acute Spinal Cord Injury in Mice

(2011) Haruo Kanno et al.   SPINE

Autophagy Is Activated in Injured Neurons and Inhibited by Methylprednisolone After Experimental Spinal Cord Injury

(2011) Hsien-Chih Chen et al.   SPINE

Biological role of matrix metalloproteinases: a critical balance

(2010) S. Loffek et al.   EUROPEAN RESPIRATORY JOURNAL

Early microvascular reactions and blood–spinal cord barrier disruption are instrumental in pathophysiology of spinal cord injury and repair: novel therapeutic strategies including nanowired drug delivery to enhance neuroprotection

(2010) Hari Shanker Sharma   JOURNAL OF NEURAL TRANSMISSION

Neisseria meningitidis Induces Brain Microvascular Endothelial Cell Detachment from the Matrix and Cleavage of Occludin: A Role for MMP-8

(2010) Alexandra Schubert-Unkmeir et al.   PLoS Pathogens

Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis

(2009) Lillian A Buhler et al.   BMC NEUROSCIENCE

Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia

(2008) Wenlan Liu et al.   JOURNAL OF NEUROCHEMISTRY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury

(2007) Dustin J. Donnelly et al.   EXPERIMENTAL NEUROLOGY