RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers
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Title
RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers
Authors
Keywords
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Journal
Frontiers in Genetics
Volume 5, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-01-09
DOI
10.3389/fgene.2014.00441
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Related references
Note: Only part of the references are listed.- The Werner syndrome protein: linking the replication checkpoint response to genome stability
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- Human RecQ Helicases in DNA Repair, Recombination, and Replication
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- RECQL1 Plays an Important Role in the Development of Tongue Squamous Cell Carcinoma
- (2014) Jiang Tao et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Human RECQL1 participates in telomere maintenance
- (2014) Venkateswarlu Popuri et al. NUCLEIC ACIDS RESEARCH
- Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase
- (2013) Andrew S. Rosenthal et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2013) Giang Huong Nguyen et al. CHEMISTRY & BIOLOGY
- A cascade leading to premature aging phenotypes including abnormal tumor profiles in Werner syndrome (Review)
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- Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition
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- RECQL1 DNA Repair Helicase: A Potential Therapeutic Target and a Proliferative Marker against Ovarian Cancer
- (2013) Sakiko Sanada et al. PLoS One
- Helicases as Prospective Targets for Anti-Cancer Therapy
- (2012) Rigu Gupta et al. Anti-Cancer Agents in Medicinal Chemistry
- DNA Repair Proteins as Molecular Targets for Cancer Therapeutics
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- MYC-Driven Tumorigenesis Is Inhibited by WRN Syndrome Gene Deficiency
- (2012) R. Moser et al. MOLECULAR CANCER RESEARCH
- Unique and important consequences of RECQ1 deficiency in mammalian cells
- (2011) Sudha Sharma et al. CELL CYCLE
- RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression
- (2011) Mahesh Ramamoorthy et al. NUCLEIC ACIDS RESEARCH
- Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress
- (2011) M. Aggarwal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The RecQ DNA Helicases in DNA Repair
- (2010) Kara A. Bernstein et al. Annual Review of Genetics
- BCR/ABL Stimulates WRN to Promote Survival and Genomic Instability
- (2010) A. Slupianek et al. CANCER RESEARCH
- Human RecQL4 Helicase Plays Critical Roles in Prostate Carcinogenesis
- (2010) Y. Su et al. CANCER RESEARCH
- The Human WRN and BLM RecQ Helicases Differentially Regulate Cell Proliferation and Survival after Chemotherapeutic DNA Damage
- (2010) F. J. Mao et al. CANCER RESEARCH
- Alternating 2′-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist
- (2009) Svetlana Hamm et al. IMMUNOBIOLOGY
- Role of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cells
- (2008) Kazunobu Futami et al. CANCER SCIENCE
- WRN Is Required for ATM Activation and the S-Phase Checkpoint in Response to Interstrand Cross-Link–Induced DNA Double-Strand Breaks
- (2008) Wen-Hsing Cheng et al. MOLECULAR BIOLOGY OF THE CELL
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