Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

The Obesity Related Gene, FTO, Interacts with APOE, and is Associated with Alzheimer's Disease Risk: A Prospective Cohort Study

(2018) Lina Keller et al.   JOURNAL OF ALZHEIMERS DISEASE

R PheWAS: data analysis and plotting tools for phenome-wide association studies in the R environment

(2014) Robert J. Carroll et al.   BIOINFORMATICS

Association of the FTO Obesity Risk Variant rs8050136 With Percentage of Energy Intake From Fat in Multiple Racial/Ethnic Populations

(2013) Sungshim Lani Park et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Fine Mapping and Identification of BMI Loci in African Americans

(2013) Jian Gong et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A PheWAS approach in studying HLA-DRB1*1501

(2013) S J Hebbring et al.   GENES AND IMMUNITY

The Electronic Medical Records and Genomics (eMERGE) Network: past, present and future

(2013) Omri Gottesman et al.   GENETICS IN MEDICINE

Genetic variation associated with circulating monocyte count in the eMERGE Network

(2013) David R. Crosslin et al.   HUMAN MOLECULAR GENETICS

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

(2013) Joshua C Denny et al.   NATURE BIOTECHNOLOGY

Genetic Variants That Confer Resistance to Malaria Are Associated with Red Blood Cell Traits in African-Americans: An Electronic Medical Record-based Genome-Wide Association Study

(2013) Keyue Ding et al.   G3-Genes Genomes Genetics

Phenome-Wide Association Study (PheWAS) for Detection of Pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

(2013) Sarah A. Pendergrass et al.   PLoS Genetics

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

(2012)   LANCET

The impact of intronic single nucleotide polymorphisms and ethnic diversity for studies on the obesity geneFTO

(2012) J. A. Jacobsson et al.   Obesity Reviews

Statistical and Biological Gene-Lifestyle Interactions of MC4R and FTO with Diet and Physical Activity on Obesity: New Effects on Alcohol Consumption

(2012) Dolores Corella et al.   PLoS One

A model of developmental evolution: selection, pleiotropy and compensation

(2012) Mihaela Pavlicev et al.   TRENDS IN ECOLOGY & EVOLUTION

Complement Receptor 1 Gene Variants Are Associated with Erythrocyte Sedimentation Rate

(2011) Iftikhar J. Kullo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Variants Near FOXE1 Are Associated with Hypothyroidism and Other Thyroid Conditions: Using Electronic Medical Records for Genome- and Phenome-wide Studies

(2011) Joshua C. Denny et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies

(2011) Catherine A McCarty et al.   BMC Medical Genomics

FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life: A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies

(2011) J. K. Hertel et al.   DIABETES

Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians

(2011) H. Li et al.   DIABETOLOGIA

The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery

(2011) S.A. Pendergrass et al.   GENETIC EPIDEMIOLOGY

Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population

(2011) Kikuko Hotta et al.   JOURNAL OF HUMAN GENETICS

Mapping clinical phenotype data elements to standardized metadata repositories and controlled terminologies: the eMERGE Network experience

(2011) Jyotishman Pathak et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

The Obesity-Associated Polymorphisms FTO rs9939609 and MC4R rs17782313 and Endometrial Cancer Risk in Non-Hispanic White Women

(2011) Galina Lurie et al.   PLoS One

The origins and evolution of genetic disease risk in modern humans

(2010) Bernard J. Crespi   Annals of the New York Academy of Sciences

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

(2010) J. C. Denny et al.   BIOINFORMATICS

Identification of Genomic Predictors of Atrioventricular Conduction

(2010) Joshua C. Denny et al.   CIRCULATION

Comparison of ICD-9–based, retrospective, and prospective assessments of perioperative complications: assessment of accuracy in reporting

(2010) Peter G. Campbell et al.   JOURNAL OF NEUROSURGERY-SPINE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Meta-analysis Added Power to Identify Variants in FTO Associated With Type 2 Diabetes and Obesity in the Asian Population

(2010) Yun Liu et al.   Obesity

Genetic studies of common types of obesity: a critique of the current use of phenotypes

(2010) M. J. Müller et al.   Obesity Reviews

Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue

(2009) L. G. Grunnet et al.   DIABETES

Avoiding the high Bonferroni penalty in genome-wide association studies

(2009) Xiaoyi Gao et al.   GENETIC EPIDEMIOLOGY

Comparison of body mass index with waist circumference, waist-to-hip ratio, and waist-to-stature ratio as a predictor of hypertension incidence in Mauritius

(2009) Regzedmaa Nyamdorj et al.   JOURNAL OF HYPERTENSION

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans

(2008) N. Klöting et al.   DIABETOLOGIA

TheFTOGene and Obesity in a Large Eastern European Population Sample: The HAPIEE Study

(2008) Jaroslav A. Hubacek et al.   Obesity

BMI Compared With Central Obesity Indicators as a Predictor of Diabetes Incidence in Mauritius

(2008) Regzedmaa Nyamdorj et al.   Obesity