TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy

Human Tumor-Infiltrating Myeloid Cells: Phenotypic and Functional Diversity

(2017) Louise A. Elliott et al.   Frontiers in Immunology

Diverse macrophages polarization in tumor microenvironment

(2016) Inmoo Rhee   ARCHIVES OF PHARMACAL RESEARCH

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

CD73 Is Associated with Poor Prognosis in High-Grade Serous Ovarian Cancer

(2015) Martin Turcotte et al.   CANCER RESEARCH

Immune Checkpoint Blockade in Cancer Therapy

(2015) Michael A. Postow et al.   JOURNAL OF CLINICAL ONCOLOGY

Reverse phase protein arrays in signaling pathways: a data integration perspective

(2015) Shixia Huang et al.   Drug Design Development and Therapy

Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage

(2015) Chi-Hsuan Chang et al.   Stem Cell Reports

Signaling pathways involved in MDSC regulation

(2014) Prashant Trikha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

A Randomized Phase II Presurgical Trial of Transdermal 4-Hydroxytamoxifen Gel versus Oral Tamoxifen in Women with Ductal Carcinoma In Situ of the Breast

(2014) O. Lee et al.   CLINICAL CANCER RESEARCH

Entering the mainstream of cancer treatment

(2014) Steven A. Rosenberg   Nature Reviews Clinical Oncology

The immune checkpoint inhibitors: where are we now?

(2014) Rachel M. Webster   NATURE REVIEWS DRUG DISCOVERY

Polarization and reprogramming of myeloid-derived suppressor cells

(2013) W.-C. Yang et al.   Journal of Molecular Cell Biology

Myeloid derived suppressor cells – a new therapeutic target in the treatment of cancer

(2013) Robert Wesolowski et al.   Journal for ImmunoTherapy of Cancer

Metabolism of L-Arginine by Myeloid-Derived Suppressor Cells in Cancer: Mechanisms of T cell suppression and Therapeutic Perspectives

(2012) Patrick Raber et al.   IMMUNOLOGICAL INVESTIGATIONS

Paired Immunoglobin-like Receptor-B Regulates the Suppressive Function and Fate of Myeloid-Derived Suppressor Cells

(2011) Ge Ma et al.   IMMUNITY

Cancer Immunotherapy Comes of Age

(2011) Suzanne L. Topalian et al.   JOURNAL OF CLINICAL ONCOLOGY

Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination

(2011) Beena Patricia Jeevan-Raj et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Simple Hanging Drop Cell Culture Protocol for Generation of 3D Spheroids

(2011) Ramsey Foty   Jove-Journal of Visualized Experiments

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

(2010) Cesar A. Corzo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells

(2010) M. G. Lechner et al.   JOURNAL OF IMMUNOLOGY

Myeloid Cells in the Tumor Microenvironment: Modulation of Tumor Angiogenesis and Tumor Inflammation

(2010) Michael C. Schmid et al.   Journal of Oncology

Immune Response During Therapy With Cisplatin or Radiation for Human Papillomavirus–Related Head and Neck Cancer

(2009) William C. Spanos et al.   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

Transforming growth factor beta (TGF-β) and inflammation in cancer

(2009) Brian Bierie et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Immune Reconstitution during Pneumocystis Lung Infection: Disruption of Surfactant Component Expression and Function by S-Nitrosylation

(2009) E. N. Atochina-Vasserman et al.   JOURNAL OF IMMUNOLOGY

The Efficacy of an IL-1α Vaccine Depends on IL-1RI Availability and Concomitant Myeloid-derived Suppressor Cell Reduction

(2009) Tobias Weiss et al.   JOURNAL OF IMMUNOTHERAPY

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Triterpenoid CDDO-Methyl Ester Inhibits the Janus-Activated Kinase-1 (JAK1)->Signal Transducer and Activator of Transcription-3 (STAT3) Pathway by Direct Inhibition of JAK1 and STAT3

(2008) R. Ahmad et al.   CANCER RESEARCH

Reversal of Myeloid Cell-Mediated Immunosuppression in Patients with Metastatic Renal Cell Carcinoma

(2008) S. Kusmartsev et al.   CLINICAL CANCER RESEARCH

Natural killer cells from protein kinase C θ−/− mice stimulated with interleukin-12 are deficient in production of interferon-γ

(2008) Karen M. Page et al.   JOURNAL OF LEUKOCYTE BIOLOGY