Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination

Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense

(2011) Min Wei et al.   NATURE IMMUNOLOGY

Activation-Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5

(2010) Rushad Pavri et al.   CELL

Immunoglobulin class switch recombination deficiencies

(2010) S. Kracker et al.   CLINICAL IMMUNOLOGY

TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis

(2010) Marielle Herzog et al.   DEVELOPMENTAL BIOLOGY

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

(2010) Arito Yamane et al.   NATURE IMMUNOLOGY

14-3-3 adaptor proteins recruit AID to 5′-AGCT-3′–rich switch regions for class switch recombination

(2010) Zhenming Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ikaros controls isotype selection during immunoglobulin class switch recombination

(2009) MacLean Sellars et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination

(2009) Isabelle Robert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination

(2009) Lili Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination

(2009) Bao Q Vuong et al.   NATURE IMMUNOLOGY

H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination

(2009) F. L. Kuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carboxy-terminal domain of AID required for its mRNA complex formation in vivo

(2009) Taichiro Nonaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence

(2009) R. Geisberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination

(2009) Tomomitsu Doi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH Translocations

(2008) Davide F. Robbiani et al.   CELL

SHMTool: A webserver for comparative analysis of somatic hypermutation datasets

(2008) Thomas MacCarthy et al.   DNA REPAIR

Disruption of the Interaction between Transcriptional Intermediary Factor 1β and Heterochromatin Protein 1 Leads to a Switch from DNA Hyper- to Hypomethylation and H3K9 to H3K27 Trimethylation on the MEST Promoter Correlating with Gene Reactivation

(2008) Raphaël Riclet et al.   MOLECULAR BIOLOGY OF THE CELL

Haploinsufficiency of Activation-Induced Deaminase for Antibody Diversification and Chromosome Translocations both In Vitro and In Vivo

(2008) Isora V. Sernández et al.   PLoS One

Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus

(2008) M. Chowdhury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA