Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome

Complement Factor D protects mice from ethanol-induced inflammation and liver injury

(2018) Rebecca L. McCullough et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Anaphylatoxin C5a induces inflammation and reduces insulin sensitivity by activating TLR4/NF-kB/PI3K signaling pathway in 3T3-L1 adipocytes

(2018) Xin-Yan Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90

(2018) Banishree Saha et al.   HEPATOLOGY

Alcohol, adipose tissue and liver disease: mechanistic links and clinical considerations

(2017) Richard Parker et al.   Nature Reviews Gastroenterology & Hepatology

Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation

(2017) Pablo Bora et al.   Stem Cell Research & Therapy

Extracellular Vesicles from Adipose Tissue—A Potential Role in Obesity and Type 2 Diabetes?

(2017) Xuan Gao et al.   Frontiers in Endocrinology

Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury

(2017) Tobias Puengel et al.   PLoS One

Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury

(2016) Sanjoy Roychowdhury et al.   HEPATOLOGY

Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles

(2016) Vikas K. Verma et al.   JOURNAL OF HEPATOLOGY

Differential contribution of complement receptor C5aR in myeloid and non-myeloid cells in chronic ethanol-induced liver injury in mice

(2016) Rebecca L. McCullough et al.   MOLECULAR IMMUNOLOGY

Complement in disease: a defence system turning offensive

(2016) Daniel Ricklin et al.   Nature Reviews Nephrology

Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis

(2016) Eric Lefebvre et al.   PLoS One

ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles

(2016) Mark A. Rider et al.   Scientific Reports

Mixed lineage kinase 3 mediates release of C-X-C motif ligand 10-bearing chemotactic extracellular vesicles from lipotoxic hepatocytes

(2015) Samar H. Ibrahim et al.   HEPATOLOGY

Effect of alcohol on adipose tissue: a review on ethanol mediated adipose tissue injury

(2015) Venkata Harini Kema et al.   Adipocyte

Chemokines and alcoholic hepatitis: are chemokines good therapeutic targets?

(2014) Bin Gao et al.   GUT

Alcohol withdrawal alleviates adipose tissue inflammation in patients with alcoholic liver disease

(2014) Cosmin S. Voican et al.   LIVER INTERNATIONAL

The complement system in human cardiometabolic disease

(2014) E. Hertle et al.   MOLECULAR IMMUNOLOGY

Adipose Inflammation and Macrophage Infiltration After Binge Ethanol and Burn Injury

(2013) Yuanyuan Qin et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2

(2013) Daniel E Croker et al.   IMMUNOLOGY AND CELL BIOLOGY

Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells

(2013) Wing-hong Kwan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Changes and Regulation of the C5a Receptor on Neutrophils during Septic Shock in Humans

(2013) H. Unnewehr et al.   JOURNAL OF IMMUNOLOGY

The Complement Anaphylatoxin C5a Receptor Contributes to Obese Adipose Tissue Inflammation and Insulin Resistance

(2013) J. Phieler et al.   JOURNAL OF IMMUNOLOGY

C5aR and C5L2 act in concert to balance immunometabolism in adipose tissue

(2013) Pegah Poursharifi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

C5L2: a controversial receptor of complement anaphylatoxin, C5a

(2012) Rui Li et al.   FASEB JOURNAL

Transfer of extracellular vesicles during immune cell-cell interactions

(2012) Cristina Gutiérrez-Vázquez et al.   IMMUNOLOGICAL REVIEWS

Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3+ regulatory T cells

(2012) Michael G Strainic et al.   NATURE IMMUNOLOGY

Functional annotation of the human fat cell secretome

(2012) Ingrid Dahlman et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Identification of a Cytochrome P4502E1/Bid/C1q-dependent Axis Mediating Inflammation in Adipose Tissue after Chronic Ethanol Feeding to Mice

(2011) Becky M. Sebastian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Validation of Novel Adipokines Released from Primary Human Adipocytes

(2011) Stefan Lehr et al.   MOLECULAR & CELLULAR PROTEOMICS

Crosstalk between Complement and Toll-Like Receptors

(2011) Wen-Chao Song   TOXICOLOGIC PATHOLOGY

Complement and Alcoholic Liver Disease: Role of C1q in the Pathogenesis of Ethanol-Induced Liver Injury in Mice

(2010) Jessica I. Cohen et al.   GASTROENTEROLOGY

Early growth response-1 attenuates liver injury and promotes hepatoprotection after carbon tetrachloride exposure in mice

(2010) Michele T. Pritchard et al.   JOURNAL OF HEPATOLOGY

Harmful effect of adipose tissue on liver lesions in patients with alcoholic liver disease

(2010) Sylvie Naveau et al.   JOURNAL OF HEPATOLOGY

Crosstalk pathways between Toll-like receptors and the complement system

(2010) George Hajishengallis et al.   TRENDS IN IMMUNOLOGY