In Silico Analysis of the Minor Histocompatibility Antigen Landscape Based on the 1000 Genomes Project

Specific T Cell Responses against Minor Histocompatibility Antigens Cannot Generally Be Explained by Absence of Their Allelic Counterparts on the Cell Surface

(2018) Helena M. Bijen et al.   PROTEOMICS

Comparison of the MHC I Immunopeptidome Repertoire of B-Cell Lymphoblasts Using Two Isolation Methods

(2018) Joël Lanoix et al.   PROTEOMICS

Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction

(2017) Jennifer G. Abelin et al.   IMMUNITY

Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response

(2017) Cornelis A.M. van Bergen et al.   JOURNAL OF CLINICAL INVESTIGATION

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity

(2017) Michal Bassani-Sternberg et al.   PLoS Computational Biology

Novel Non-Histocompatibility Antigen Mismatched Variants Improve the Ability to Predict Antibody-Mediated Rejection Risk in Kidney Transplant

(2017) Silvia Pineda et al.   Frontiers in Immunology

Dynamical system modeling to simulate donor T cell response to whole exome sequencing-derived recipient peptides: Understanding randomness in alloreactivity incidence following stem cell transplantation

(2017) Vishal Koparde et al.   PLoS One

Genome-wide minor histocompatibility matching as related to the risk of graft-versus-host disease

(2016) Paul J. Martin et al.   BLOOD

Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers

(2016) D P Granados et al.   LEUKEMIA

Blinatumomab: a CD19/CD3 bispecific T cell engager (BiTE) with unique anti-tumor efficacy

(2016) Maria-Elisabeth Goebeler et al.   LEUKEMIA & LYMPHOMA

Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy

(2016) Bracha Shraibman et al.   MOLECULAR & CELLULAR PROTEOMICS

High-sensitivity HLA class I peptidome analysis enables a precise definition of peptide motifs and the identification of peptides from cell lines and patients’ sera

(2016) Danilo Ritz et al.   PROTEOMICS

A large fraction of HLA class I ligands are proteasome-generated spliced peptides

(2016) Juliane Liepe et al.   SCIENCE

Targeting of cancer neoantigens with donor-derived T cell receptor repertoires

(2016) E. Stronen et al.   SCIENCE

Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames

(2016) Céline M. Laumont et al.   Nature Communications

Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

(2016) Michal Bassani-Sternberg et al.   Nature Communications

NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasets

(2016) Morten Nielsen et al.   Genome Medicine

Autosomal Minor Histocompatibility Antigens: How Genetic Variants Create Diversity in Immune Targets

(2016) Marieke Griffioen et al.   Frontiers in Immunology

Complete Regression of Metastatic Cervical Cancer After Treatment With Human Papillomavirus–Targeted Tumor-Infiltrating T Cells

(2015) Sanja Stevanović et al.   JOURNAL OF CLINICAL ONCOLOGY

Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

(2015) Michal Bassani-Sternberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Allo-reactive T cells for the treatment of hematological malignancies

(2015) J.H.F. Falkenburg et al.   Molecular Oncology

A TCR-mimic antibody to WT1 bypasses tyrosine kinase inhibitor resistance in human BCR-ABL+ leukemias

(2014) L. Dubrovsky et al.   BLOOD

Whole exome sequencing to estimate alloreactivity potential between donors and recipients in stem cell transplantation

(2014) Juliana K. Sampson et al.   BRITISH JOURNAL OF HAEMATOLOGY

Identification of minor histocompatibility antigens based on the 1000 Genomes Project

(2014) R. Oostvogels et al.   HAEMATOLOGICA

Accurate quantitation of MHC-bound peptides by application of isotopically labeled peptide MHC complexes

(2014) Chopie Hassan et al.   Journal of Proteomics

Mapping the HLA ligandome landscape of acute myeloid leukemia: a targeted approach toward peptide-based immunotherapy

(2014) C Berlin et al.   LEUKEMIA

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

(2014) Matthew M. Gubin et al.   NATURE

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

(2014) Mahesh Yadav et al.   NATURE

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

(2014) Shannon L. Maude et al.   NEW ENGLAND JOURNAL OF MEDICINE

HLA Diversity in the 1000 Genomes Dataset

(2014) Pierre-Antoine Gourraud et al.   PLoS One

Expanding the detectable HLA peptide repertoire using electron-transfer/higher-energy collision dissociation (EThcD)

(2014) G. P. M. Mommen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides

(2014) Diana Paola Granados et al.   Nature Communications

In silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem-Cell Transplant Donors and Recipients: Understanding the Quantitative Immunobiology of Allogeneic Transplantation

(2014) Max Jameson-Lee et al.   Frontiers in Immunology

The Human Leukocyte Antigen–presented Ligandome of B Lymphocytes

(2013) Chopie Hassan et al.   MOLECULAR & CELLULAR PROTEOMICS

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes

(2013) S. Kumari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors

(2012) Emmet McCormack et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Generation and administration of HA-1-specific T-cell lines for the treatment of patients with relapsed leukemia after allogeneic stem cell transplantation: a pilot study

(2012) P. Meij et al.   HAEMATOLOGICA

A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

(2012) D. G. MacArthur et al.   SCIENCE

Exploiting T cells specific for human minor histocompatibility antigens for therapy of leukemia

(2011) Marie Bleakley et al.   IMMUNOLOGY AND CELL BIOLOGY

High-Throughput Identification of Potential Minor Histocompatibility Antigens by MHC Tetramer-Based Screening: Feasibility and Limitations

(2011) Pleun Hombrink et al.   PLoS One

Common Minor Histocompatibility Antigen Discovery Based upon Patient Clinical Outcomes and Genomic Data

(2011) Paul M. Armistead et al.   PLoS One

Graft versus Leukemia Reactivity after Allogeneic Stem Cell Transplantation

(2010) J.H. Frederik Falkenburg et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens

(2010) E. H. Warren et al.   BLOOD

Loss of Mismatched HLA in Leukemia after Stem-Cell Transplantation

(2009) Luca Vago et al.   NEW ENGLAND JOURNAL OF MEDICINE

Graft-versus-leukemia effects of transplantation and donor lymphocytes

(2008) H.-J. Kolb   BLOOD