Expression of DP2 (CRTh2), a Prostaglandin D2 Receptor, in Human Mast Cells

A G protein–coupled receptor and the intracellular synthase of its agonist functionally cooperate

(2014) Chantal Binda et al.   JOURNAL OF CELL BIOLOGY

Conformational biosensors reveal GPCR signalling from endosomes

(2013) Roshanak Irannejad et al.   NATURE

Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2–DP1 receptor paracrine axis

(2013) Yoshitaka Taketomi et al.   NATURE IMMUNOLOGY

The single nucleotide polymorphismCRTh2rs533116 is associated with allergic asthma and increased expression of CRTh2

(2012) E. Campos Alberto et al.   ALLERGY

Expression of nitric oxide synthases in leukocytes in nasal polyps

(2012) Tsuyoshi Yoshimura et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

The Inhibitory G Protein Gi Identified as Pertussis Toxin-Catalyzed ADP-Ribosylation

(2012) Toshiaki Katada   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Limited replication of influenza A virus in human mast cells

(2012) Candy W. Marcet et al.   IMMUNOLOGIC RESEARCH

Microenvironmental regulation of inducible nitric oxide synthase expression and nitric oxide production in mouse bone marrow-derived mast cells

(2012) T. C. Moon et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The opposing role of two prostaglandin D2 receptors, DP and CRTH2, in human eosinophil migration

(2011) Takahito Chiba et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

R2D2 for C4Eo: an ‘alliance’ of PGD2 receptors is required for LTC4 production by human eosinophils

(2011) Graham A Mackay et al.   BRITISH JOURNAL OF PHARMACOLOGY

IFN-γ and TNF-α potentiate prostaglandin D2-induced human eosinophil chemotaxis through up-regulation of CRTH2 surface receptor

(2011) A.E. El-Shazly et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Accumulation of CRTH2-positive leukocytes in human allergic nasal mucosa

(2010) Hideaki Shirasaki et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Co-operative signalling through DP1 and DP2 prostanoid receptors is required to enhance leukotriene C4 synthesis induced by prostaglandin D2 in eosinophils

(2010) FP Mesquita-Santos et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protein Tyrosine Nitration of Aldolase in Mast Cells: A Plausible Pathway in Nitric Oxide-Mediated Regulation of Mast Cell Function

(2010) Y. Sekar et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Type I IFN Reverses Human Th2 Commitment and Stability by Suppressing GATA3

(2010) J. P. Huber et al.   JOURNAL OF IMMUNOLOGY

Characterization of C-terminal tail determinants involved in CRTH2 receptor trafficking: Identification of a recycling motif

(2009) Sébastien J. Roy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Advances in mast cell biology: new understanding of heterogeneity and function

(2009) T C Moon et al.   Mucosal Immunology

Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2

(2008) R. Schuligoi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Discovery of a New Class of Potent, Selective, and Orally Bioavailable CRTH2 (DP2) Receptor Antagonists for the Treatment of Allergic Inflammatory Diseases#

(2008) Stefano Crosignani et al.   JOURNAL OF MEDICINAL CHEMISTRY

Lipopolysaccharide Induces Macrophage Migration via Prostaglandin D2 and Prostaglandin E2

(2008) T. Tajima et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS