Curcumin-loaded self-nanomicellizing solid dispersion system: part II: in vivo safety and efficacy assessment against behavior deficit in Alzheimer disease

Self-nanomicellizing solid dispersion of edaravone: part II: in vivo assessment of efficacy against behavior deficits and safety in Alzheimer’s disease model

(2018) Ankit Parikh et al.   Drug Design Development and Therapy

Self-nanomicellizing solid dispersion of edaravone: part I – oral bioavailability improvement

(2018) Ankit Parikh et al.   Drug Design Development and Therapy

Curcumin-loaded self-nanomicellizing solid dispersion system: part I: development, optimization, characterization, and oral bioavailability

(2018) Ankit Parikh et al.   Drug Delivery and Translational Research

Mice with Sort1 deficiency display normal cognition but elevated anxiety-like behavior

(2016) Chun-Sheng Ruan et al.   EXPERIMENTAL NEUROLOGY

Development of a novel oral delivery system of edaravone for enhancing bioavailability

(2016) Ankit Parikh et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Impaired Dendritic Development and Memory in Sorbs2 Knock-Out Mice

(2016) Q. Zhang et al.   JOURNAL OF NEUROSCIENCE

A cannabinoid link between mitochondria and memory

(2016) Etienne Hebert-Chatelain et al.   NATURE

A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice

(2016) Andrea Wolf et al.   PLoS One

Microparticles Containing Curcumin Solid Dispersion: Stability, Bioavailability and Anti-Inflammatory Activity

(2015) C. C. C. Teixeira et al.   AAPS PHARMSCITECH

New Drugs from Marine Organisms in Alzheimer’s Disease

(2015) Patrizia Russo et al.   Marine Drugs

p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer’s disease

(2015) X-Q Yao et al.   MOLECULAR PSYCHIATRY

Enhanced Bioavailability and Anticancer Effect of Curcumin-Loaded Electrospun Nanofiber: In Vitro and In Vivo Study

(2015) Chuan Wang et al.   Nanoscale Research Letters

Enhanced oral bioavailability and anticancer activity of novel curcumin loaded mixed micelles in human lung cancer cells

(2015) Sharvil Patil et al.   PHYTOMEDICINE

Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits

(2015) Shu-Sheng Jiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute and sub-chronic toxicity studies of honokiol microemulsion

(2015) Qianqian Zhang et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Enhanced Bioavailability and Anticancer Effect of Curcumin-Loaded Electrospun Nanofiber: In Vitro and In Vivo Study

(2015) Chuan Wang et al.   Nanoscale Research Letters

Alzheimer disease therapeutics: Focus on the disease and not just plaques and tangles

(2014) Khalid Iqbal et al.   BIOCHEMICAL PHARMACOLOGY

Acute and sub-chronic oral toxicity profiles of the aqueous extract of Cortex Dictamni in mice and rats

(2014) Lili Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014

(2014) L. S. Schneider et al.   JOURNAL OF INTERNAL MEDICINE

Effects of (−)Epicatechin on the Pathology of APP/PS1 Transgenic Mice

(2014) Yue-Qin Zeng et al.   Frontiers in Neurology

Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model via Canonical Wnt/β-Catenin Pathway

(2013) Shashi Kant Tiwari et al.   ACS Nano

Mechanisms and effects of curcumin on spatial learning and memory improvement in APPswe/PS1dE9 mice

(2013) Pengwen Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Animal Models of Alzheimer Disease

(2013) F. M. LaFerla et al.   Cold Spring Harbor Perspectives in Medicine

Modeling Alzheimer’s disease: from past to future

(2013) Claudia Saraceno et al.   Frontiers in Pharmacology

Anticoagulant activities of curcumin and its derivative

(2012) Dong-Chan Kim et al.   BMB Reports

Acute and sub-chronic (28days) oral toxicity evaluation of hydroethanolic extract of Bridelia ferruginea Benth root bark in male rodent animals

(2012) Batomayena Bakoma et al.   FOOD AND CHEMICAL TOXICOLOGY

Mice fed on a diet enriched with genetically engineered multivitamin corn show no sub-acute toxic effects and no sub-chronic toxicity

(2012) Gemma Arjó et al.   PLANT BIOTECHNOLOGY JOURNAL

Overstimulation of newborn mice leads to behavioral differences and deficits in cognitive performance

(2012) D. A. Christakis et al.   Scientific Reports

Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

(2012) John M Ringman et al.   Alzheimers Research & Therapy

Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease

(2011) Patrizia Mecocci et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NIA Commentary: Translational Issues in Alzheimer’s Disease Drug Development

(2011) Neil S Buckholtz et al.   NEUROPSYCHOPHARMACOLOGY

Alzheimer's disease: clinical trials and drug development

(2010) Francesca Mangialasche et al.   LANCET NEUROLOGY

The effect of curcumin (turmeric) onAlzheimer′s disease: An overview

(2009) Shrikant Mishra et al.   Annals of Indian Academy of Neurology

Consumption of Grape Seed Extract Prevents Amyloid-β Deposition and Attenuates Inflammation in Brain of an Alzheimer’s Disease Mouse

(2009) Yan-Jiang Wang et al.   NEUROTOXICITY RESEARCH

Intramuscular delivery of a single chain antibody gene reduces brain Aβ burden in a mouse model of Alzheimer's disease

(2007) Yan-Jiang Wang et al.   NEUROBIOLOGY OF AGING