Hypophosphatemic Rickets: Revealing Novel Control Points for Phosphate Homeostasis
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Hypophosphatemic Rickets: Revealing Novel Control Points for Phosphate Homeostasis
Authors
Keywords
Phosphate, Hypophosphatemia, Hyperphosphatemia, Osteomalacia, FGF23, αKlotho, Mineralization, Rickets, Furin, Fam20c, DMP1, ENPP1, GALNT3
Journal
Current Osteoporosis Reports
Volume 12, Issue 3, Pages 252-262
Publisher
Springer Nature
Online
2014-06-30
DOI
10.1007/s11914-014-0223-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Randomized trial of the anti-FGF23 antibody KRN23 in X-linked hypophosphatemia
- (2014) Thomas O. Carpenter et al. JOURNAL OF CLINICAL INVESTIGATION
- Hereditary deletion of the entireFAM20Cgene in a patient with Raine syndrome
- (2013) Farouq K. Ababneh et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy
- (2013) Chad D. Touchberry et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Dosage Effect of a Phex Mutation in a Murine Model of X-Linked Hypophosphatemia
- (2013) Shoji Ichikawa et al. CALCIFIED TISSUE INTERNATIONAL
- Effects of Extracellular Phosphate on Gene Expression in Murine Osteoblasts
- (2013) C. Rendenbach et al. CALCIFIED TISSUE INTERNATIONAL
- Calcium Regulates FGF-23 Expression in Bone
- (2013) Valentin David et al. ENDOCRINOLOGY
- Exome sequencing reveals FAM20c mutations associated with fibroblast growth factor 23-related hypophosphatemia, dental anomalies, and ectopic calcification
- (2013) Silje Hjorth Rafaelsen et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Effects of iron deficiency anemia and its treatment on fibroblast growth factor 23 and phosphate homeostasis in women
- (2013) Myles Wolf et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Neonatal Iron Deficiency Causes Abnormal Phosphate Metabolism by Elevating FGF23 in Normal and ADHR Mice
- (2013) Erica L Clinkenbeard et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Plasma FGF23 levels increase rapidly after acute kidney injury
- (2013) Marta Christov et al. KIDNEY INTERNATIONAL
- Effect of ferric carboxymaltose on serum phosphate and C-terminal FGF23 levels in non-dialysis chronic kidney disease patients: post-hoc analysis of a prospective study
- (2013) Merche Prats et al. BMC Nephrology
- Parathyroid-Specific Deletion of Klotho Unravels a Novel Calcineurin-Dependent FGF23 Signaling Pathway That Regulates PTH Secretion
- (2013) Hannes Olauson et al. PLoS Genetics
- Hexa-D-arginine treatment increases 7B2•PC2 activity inhyp-mouse osteoblasts and rescues theHYPphenotype
- (2012) Baozhi Yuan et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Nuclear fibroblast growth factor 2 (FGF2) isoforms inhibit bone marrow stromal cell mineralization through FGF23/FGFR/MAPK in vitro
- (2012) Liping Xiao et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Mechanism of FGF23 processing in fibrous dysplasia
- (2012) Nisan Bhattacharyya et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia
- (2012) Nilana MT Barros et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Circulating αKlotho influences phosphate handling by controlling FGF23 production
- (2012) Rosamund C. Smith et al. JOURNAL OF CLINICAL INVESTIGATION
- Targeted Deletion of Klotho in Kidney Distal Tubule Disrupts Mineral Metabolism
- (2012) H. Olauson et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Altered Bone Development and an Increase in FGF-23 Expression in Enpp1−/− Mice
- (2012) Neil Charles Wallace Mackenzie et al. PLoS One
- Protective Roles of DMP1 in High Phosphate Homeostasis
- (2012) Afsaneh Rangiani et al. PLoS One
- The Raine Syndrome Protein FAM20C Is a Golgi Kinase That Phosphorylates Bio-Mineralization Proteins
- (2012) Hiroyuki O. Ishikawa et al. PLoS One
- Secreted Kinase Phosphorylates Extracellular Proteins That Regulate Biomineralization
- (2012) V. S. Tagliabracci et al. SCIENCE
- Inactivation of a Novel FGF23 Regulator, FAM20C, Leads to Hypophosphatemic Rickets in Mice
- (2012) Xiaofang Wang et al. PLoS Genetics
- Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo
- (2011) Yumie Rhee et al. BONE
- Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) Protein Regulates Osteoblast Differentiation
- (2011) Hwa Kyung Nam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- APhexmutation in a murine model of X-linked hypophosphatemia alters phosphate responsiveness of bone cells
- (2011) Shoji Ichikawa et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Iron Modifies Plasma FGF23 Differently in Autosomal Dominant Hypophosphatemic Rickets and Healthy Humans
- (2011) Erik A. Imel et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- FGF23 induces left ventricular hypertrophy
- (2011) Christian Faul et al. JOURNAL OF CLINICAL INVESTIGATION
- Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice
- (2011) E. G. Farrow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autosomal-Recessive Hypophosphatemic Rickets Is Associated with an Inactivation Mutation in the ENPP1 Gene
- (2010) Varda Levy-Litan et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Loss-of-Function ENPP1 Mutations Cause Both Generalized Arterial Calcification of Infancy and Autosomal-Recessive Hypophosphatemic Rickets
- (2010) Bettina Lorenz-Depiereux et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype
- (2010) Hua Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The biological function of DMP-1 in osteocyte maturation is mediated by its 57-kDa c-terminal fragment
- (2010) Yongbo Lu et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Treatment of X-Linked Hypophosphatemia with Calcitriol and Phosphate Increases Circulating Fibroblast Growth Factor 23 Concentrations
- (2010) Erik A. Imel et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population
- (2009) Majd A.I. Mirza et al. ATHEROSCLEROSIS
- Ablation of theGalnt3Gene Leads to Low-Circulating Intact Fibroblast Growth Factor 23 (Fgf23) Concentrations and Hyperphosphatemia Despite IncreasedFgf23Expression
- (2009) Shoji Ichikawa et al. ENDOCRINOLOGY
- Klotho is a substrate for α-, β- and γ-secretase
- (2009) Laura Bloch et al. FEBS LETTERS
- Defective O-Glycosylation due to a Novel Homozygous S129P Mutation Is Associated with Lack of Fibroblast Growth Factor 23 Secretion and Tumoral Calcinosis
- (2009) Clemens Bergwitz et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- FGF23 Elevation and Hypophosphatemia after Intravenous Iron Polymaltose: A Prospective Study
- (2009) Belinda J. Schouten et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Circulating Fibroblast Growth Factor 23 in Patients with End-Stage Renal Disease Treated by Peritoneal Dialysis Is Intact and Biologically Active
- (2009) Takashi Shimada et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Initial FGF23-Mediated Signaling Occurs in the Distal Convoluted Tubule
- (2009) E. G. Farrow et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation
- (2009) R. Goetz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular analysis of DMP1 mutants causing autosomal recessive hypophosphatemic rickets
- (2008) Emily G. Farrow et al. BONE
- Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis
- (2008) Orlando M. Gutiérrez et al. NEW ENGLAND JOURNAL OF MEDICINE
- A translocation causing increased -Klotho level results in hypophosphatemic rickets and hyperparathyroidism
- (2008) C. A. Brownstein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started