Sclerosing Bone Dysplasias: Leads Toward Novel Osteoporosis Treatments

Osteomesopyknosis: A Case Report and Review of Sclerosing Bone Disorders

(2014) Ada Yao et al.   Endocrine Practice

Emerging therapeutic targets for osteoporosis treatment

(2014) Minglei Chen et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Two Years of Denosumab and Teriparatide Administration in Postmenopausal Women With Osteoporosis (The DATA Extension Study): A Randomized Controlled Trial

(2014) Benjamin Z. Leder et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Romosozumab in Postmenopausal Women with Low Bone Mineral Density

(2014) Michael R. McClung et al.   NEW ENGLAND JOURNAL OF MEDICINE

Implications of Osteoblast-Osteoclast Interactions in the Management of Osteoporosis by Antiresorptive Agents Denosumab and Odanacatib

(2014) Natalie A. Sims et al.   Current Osteoporosis Reports

Hereditary deletion of the entireFAM20Cgene in a patient with Raine syndrome

(2013) Farouq K. Ababneh et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

No mutations in the serotonin related TPH1 and HTR1B genes in patients with monogenic sclerosing bone disorders

(2013) Eveline Boudin et al.   BONE

Exome sequencing identifies CTSK mutations in patients originally diagnosed as intermediate osteopetrosis

(2013) Alessandra Pangrazio et al.   BONE

Localization of the gene for X-linked calvarial hyperostosis to chromosome Xq27.3–Xqter

(2013) V.M. Borra et al.   BONE

Localization of the Gene for Hyperostosis Cranialis Interna to Chromosome 8p21 with Analysis of Three Candidate Genes

(2013) V. M. Borra et al.   CALCIFIED TISSUE INTERNATIONAL

Genetics in Endocrinology: Autosomal dominant osteopetrosis revisited: lessons from recent studies

(2013) Jens Bollerslev et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

ReversingLRP5-Dependent Osteoporosis andSOSTDeficiency-Induced Sclerosing Bone Disorders by Altering WNT Signaling Activity

(2013) Ming-Kang Chang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Serum Dickkopf 1 Levels in Sclerostin Deficiency

(2013) A. H. van Lierop et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Osteopetrosis: genetics, treatment and new insights into osteoclast function

(2013) Cristina Sobacchi et al.   Nature Reviews Endocrinology

Next-generation sequencing: a frameshift in skeletal dysplasia gene discovery

(2013) S. Lazarus et al.   OSTEOPOROSIS INTERNATIONAL

A Novel Autosomal Recessive GJA1 Missense Mutation Linked to Craniometaphyseal Dysplasia

(2013) Ying Hu et al.   PLoS One

Sclerostin Inhibition Reverses Skeletal Fragility in an Lrp5-Deficient Mouse Model of OPPG Syndrome

(2013) R. Kedlaya et al.   Science Translational Medicine

The role of extracellular modulators of canonical Wnt signaling in bone metabolism and diseases

(2013) Eveline Boudin et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Mutations in sFRP1 or sFRP4 are not a common cause of craniotubular hyperostosis

(2012) Eveline Boudin et al.   BONE

V-ATPases in osteoclasts: Structure, function and potential inhibitors of bone resorption

(2012) A. Qin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Odanacatib in the treatment of postmenopausal women with low bone mineral density: Five years of continued therapy in a phase 2 study

(2012) Bente Langdahl et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin antibody improves skeletal parameters in a Brtl/+ mouse model of osteogenesis imperfecta

(2012) Benjamin P Sinder et al.   JOURNAL OF BONE AND MINERAL RESEARCH

AnSNX10mutation causes malignant osteopetrosis of infancy

(2012) Memet Aker et al.   JOURNAL OF MEDICAL GENETICS

Inactivation of a Novel FGF23 Regulator, FAM20C, Leads to Hypophosphatemic Rickets in Mice

(2012) Xiaofang Wang et al.   PLoS Genetics

Identification of signal peptide domain SOST mutations in autosomal dominant craniodiaphyseal dysplasia

(2011) Su Jin Kim et al.   HUMAN GENETICS

Bone Overgrowth-associated Mutations in theLRP4Gene Impair Sclerostin Facilitator Function

(2011) Olivier Leupin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

Calvarial hyperostosis: a benign X-linked recessive disorder

(2010) Roberta A. Pagon et al.   CLINICAL GENETICS

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

(2010) Janel O. Johnson et al.   NEURON

Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: Part II

(2009) William J. Moore et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel and recurrent germlineLEMD3mutations causing Buschke-Ollendorff syndrome and osteopoikilosis but not isolated melorheostosis

(2009) Y Zhang et al.   CLINICAL GENETICS

Human Osteoclast-Poor Osteopetrosis with Hypogammaglobulinemia due to TNFRSF11A (RANK) Mutations

(2008) Matteo M. Guerrini et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human genetics of osteoporosis

(2008) Serge Ferrari   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Modulation of Wnt Signaling Through Inhibition of Secreted Frizzled-Related Protein I (sFRP-1) with N-Substituted Piperidinyl Diphenylsulfonyl Sulfonamides†

(2008) William J. Moore et al.   JOURNAL OF MEDICINAL CHEMISTRY

Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis

(2008) Zandra A Jenkins et al.   NATURE GENETICS