Investigation of post-translational modifications in type 2 diabetes

Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorial

(2018) Christina Ludwig et al.   Molecular Systems Biology

Global Phosphoproteomic Analysis of Insulin/Akt/mTORC1/S6K Signaling in Rat Hepatocytes

(2017) Yuanyuan Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation

(2016) Marta Szabat et al.   Cell Metabolism

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle

(2016) Urszula Chursa et al.   DIABETOLOGIA

Mass spectrometry-based proteomic quest for diabetes biomarkers

(2015) Shiying Shao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Mitochondrial complex I defect and increased fatty acid oxidation enhance protein lysine acetylation in the diabetic heart

(2015) Edwin J. Vazquez et al.   CARDIOVASCULAR RESEARCH

Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure

(2015) Kosaku Shinoda et al.   Cell Metabolism

Removal of Abnormal MyofilamentO-GlcNAcylation Restores Ca2+Sensitivity in Diabetic Cardiac Muscle

(2015) Genaro A. Ramirez-Correa et al.   DIABETES

Quantitative Phosphoproteomics Revealed Glucose-Stimulated Responses of Islet Associated with Insulin Secretion

(2015) Jiaming Li et al.   JOURNAL OF PROTEOME RESEARCH

Terminal Galactosylation and Sialylation Switching on Membrane Glycoproteins upon TNF-Alpha-Induced Insulin Resistance in Adipocytes

(2015) Benjamin L. Parker et al.   MOLECULAR & CELLULAR PROTEOMICS

Dissection of metabolic pathways in the Db/Db mouse model by integrative proteome and acetylome analysis

(2015) Soraya Hölper et al.   Molecular BioSystems

Diabetes-associated dysregulation ofO-GlcNAcylation in rat cardiac mitochondria

(2015) Partha S. Banerjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

One-pot synthesis of magnetic colloidal nanocrystal clusters coated with chitosan for selective enrichment of glycopeptides

(2014) Chunli Fang et al.   ANALYTICA CHIMICA ACTA

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling

(2014) Osama Abo Alrob et al.   CARDIOVASCULAR RESEARCH

Detecting O-GlcNAc using in vitro sulfation

(2014) Zhengliang L Wu et al.   GLYCOBIOLOGY

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Genetic Control of Differential Acetylation in Diabetic Rats

(2014) Pamela J. Kaisaki et al.   PLoS One

Role of advanced glycation end products in cellular signaling

(2014) Christiane Ott et al.   Redox Biology

Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases

(2014) Brent J. Ryan et al.   Redox Biology

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

(2013) Sean J. Humphrey et al.   Cell Metabolism

ProteinO-GlcNAcylation in diabetes and diabetic complications

(2013) Junfeng Ma et al.   Expert Review of Proteomics

Proteome Wide Purification and Identification of O-GlcNAc-Modified Proteins Using Click Chemistry and Mass Spectrometry

(2013) Hannes Hahne et al.   JOURNAL OF PROTEOME RESEARCH

Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

(2013) Jeffrey R. Erickson et al.   NATURE

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

β-cell dedifferentiation in diabetes is important, but what is it?

(2013) Gordon C Weir et al.   Islets

O-GlcNAc Transferase/Host Cell Factor C1 Complex Regulates Gluconeogenesis by Modulating PGC-1α Stability

(2012) Hai-Bin Ruan et al.   Cell Metabolism

Maintenance of  -Cell Maturity and Plasticity in the Adult Pancreas: Developmental Biology Concepts in Adult Physiology

(2012) M. Szabat et al.   DIABETES

HLA-dependent autoantibodies against post-translationally modified collagen type II in type 1 diabetes mellitus

(2012) R. Strollo et al.   DIABETOLOGIA

O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

(2012) Shalini Pathak et al.   EMBO JOURNAL

Implementation of proteomic biomarkers: making it work

(2012) Harald Mischak et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Acetylation of Retinal Histones in Diabetes Increases Inflammatory Proteins

(2012) Chandra Sekhar Rao Kadiyala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stable Isotope Labeling with Amino Acids in Drosophila for Quantifying Proteins and Modifications

(2012) Ping Xu et al.   JOURNAL OF PROTEOME RESEARCH

Global Identification and Characterization of BothO-GlcNAcylation and Phosphorylation at the Murine Synapse

(2012) Jonathan C. Trinidad et al.   MOLECULAR & CELLULAR PROTEOMICS

Electron transfer dissociation mass spectrometry in proteomics

(2012) Min-Sik Kim et al.   PROTEOMICS

Induction of lactadherin mediates the apoptosis of endothelial cells in response to advanced glycation end products and protective effects of grape seed procyanidin B2 and resveratrol

(2011) Bao-ying Li et al.   APOPTOSIS

Comprehensive Identification of Glycated Peptides and Their Glycation Motifs in Plasma and Erythrocytes of Control and Diabetic Subjects

(2011) Qibin Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Ultra High Resolution Linear Ion Trap Orbitrap Mass Spectrometer (Orbitrap Elite) Facilitates Top Down LC MS/MS and Versatile Peptide Fragmentation Modes

(2011) Annette Michalski et al.   MOLECULAR & CELLULAR PROTEOMICS

Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody

(2010) Scott A. Yuzwa et al.   AMINO ACIDS

Quantitative Proteomics Reveals Subset-Specific Viral Recognition in Dendritic Cells

(2010) Christian A. Luber et al.   IMMUNITY

Quantitative Phosphoproteomic Analysis of T Cell Receptor Signaling in Diabetes Prone and Resistant Mice

(2010) Leo K. Iwai et al.   JOURNAL OF PROTEOME RESEARCH

Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc

(2010) Chin Fen Teo et al.   Nature Chemical Biology

Super-SILAC mix for quantitative proteomics of human tumor tissue

(2010) Tamar Geiger et al.   NATURE METHODS

Decoding signalling networks by mass spectrometry-based proteomics

(2010) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: A mass spectrometric approach

(2010) Veerle De Corte et al.   PROTEIN SCIENCE

Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle

(2009) K. Højlund et al.   DIABETOLOGIA

Bioinformatics analysis of mass spectrometry-based proteomics data sets

(2009) Chanchal Kumar et al.   FEBS LETTERS

iTRAQ Underestimation in Simple and Complex Mixtures: “The Good, the Bad and the Ugly”

(2009) Saw Yen Ow et al.   JOURNAL OF PROTEOME RESEARCH

A Robust Error Model for iTRAQ Quantification Reveals Divergent Signaling between Oncogenic FLT3 Mutants in Acute Myeloid Leukemia

(2009) Yi Zhang et al.   MOLECULAR & CELLULAR PROTEOMICS

O-LinkedN-Acetylglucosamine Modification of Insulin Receptor Substrate-1 Occurs in Close Proximity to Multiple SH2 Domain Binding Motifs

(2009) Amanda L. Klein et al.   MOLECULAR & CELLULAR PROTEOMICS

In-depth Qualitative and Quantitative Profiling of Tyrosine Phosphorylation Using a Combination of Phosphopeptide Immunoaffinity Purification and Stable Isotope Dimethyl Labeling

(2009) Paul J. Boersema et al.   MOLECULAR & CELLULAR PROTEOMICS

A Dual Pressure Linear Ion Trap Orbitrap Instrument with Very High Sequencing Speed

(2009) Jesper V. Olsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Enrichment and Site Mapping ofO-LinkedN-Acetylglucosamine by a Combination of Chemical/Enzymatic Tagging, Photochemical Cleavage, and Electron Transfer Dissociation Mass Spectrometry

(2009) Zihao Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics

(2009) Paul J Boersema et al.   Nature Protocols

Evidence for phosphorylation of serine 753 in CFTR using a novel metal-ion affinity resin and matrix-assisted laser desorption mass spectrometry

(2009) David C. A. Neville et al.   PROTEIN SCIENCE

SILAC Mouse for Quantitative Proteomics Uncovers Kindlin-3 as an Essential Factor for Red Blood Cell Function

(2008) Marcus Krüger et al.   CELL

Site-Specific GlcNAcylation of Human Erythrocyte Proteins: Potential Biomarker(s) for Diabetes

(2008) Z. Wang et al.   DIABETES

O-GlcNAc Regulates FoxO Activation in Response to Glucose

(2008) Michael P. Housley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specific Phosphopeptide Enrichment with Immobilized Titanium Ion Affinity Chromatography Adsorbent for Phosphoproteome Analysis

(2008) Houjiang Zhou et al.   JOURNAL OF PROTEOME RESEARCH

Absolute SILAC for Accurate Quantitation of Proteins in Complex Mixtures Down to the Attomole Level

(2008) Stefan Hanke et al.   JOURNAL OF PROTEOME RESEARCH

An Assessment of Software Solutions for the Analysis of Mass Spectrometry Based Quantitative Proteomics Data

(2008) Lukas N. Mueller et al.   JOURNAL OF PROTEOME RESEARCH

Hydrophilic Interaction Chromatography Reduces the Complexity of the Phosphoproteome and Improves Global Phosphopeptide Isolation and Detection

(2008) Dean E. McNulty et al.   MOLECULAR & CELLULAR PROTEOMICS

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

(2008) Xiaoyong Yang et al.   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

(2008) Michael L Nielsen et al.   NATURE METHODS

Hepatic Glucose Sensing via the CREB Coactivator CRTC2

(2008) R. Dentin et al.   SCIENCE