The Spectrum of Anti-Chromatin/Nucleosome Autoantibodies: Independent and Interdependent Biomarkers of Disease

Review: Antinucleosome Antibodies: A Critical Reflection on Their Specificities and Diagnostic Impact

(2014) Ole Petter Rekvig et al.   Arthritis & Rheumatology

Extracellular DNA traps in allergic, infectious, and autoimmune diseases

(2013) D. Simon et al.   ALLERGY

NETosis: how vital is it?

(2013) B. G. Yipp et al.   BLOOD

Neutrophils Recruited to Sites of Infection Protect from Virus Challenge by Releasing Neutrophil Extracellular Traps

(2013) Craig N. Jenne et al.   Cell Host & Microbe

Nuclear Antigens and Auto/Alloantibody Responses: Friend or Foe in Transplant Immunology

(2013) Toshiaki Nakano et al.   Clinical & Developmental Immunology

Major pathogenic steps in human lupus can be effectively suppressed by nucleosomal histone peptide epitope-induced regulatory immunity

(2013) Li Zhang et al.   CLINICAL IMMUNOLOGY

Autoantibody Induction by DNA-Containing Immune Complexes Requires HMGB1 with the TLR2/MicroRNA-155 Pathway

(2013) Z. Wen et al.   JOURNAL OF IMMUNOLOGY

Damage-Associated Molecular Patterns Control Neutrophil Recruitment

(2013) Keir Pittman et al.   Journal of Innate Immunity

The Role of Microparticles in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus

(2013) J. R. Dye et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

(2012) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Are anti-nucleosome antibodies a better diagnostic marker than anti-dsDNA antibodies for systemic lupus erythematosus? A systematic review and a study of metanalysis

(2012) Nicola Bizzaro et al.   AUTOIMMUNITY REVIEWS

NETs Tangle with HIV

(2012) Craig N. Jenne et al.   Cell Host & Microbe

Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis

(2012) Braedon McDonald et al.   Cell Host & Microbe

The origin and properties of extracellular DNA: From PAMP to DAMP

(2012) David S. Pisetsky   CLINICAL IMMUNOLOGY

High mobility group box chromosomal protein 1 in acute-on-chronic liver failure patients and mice with ConA-induced acute liver injury

(2012) Rong-Rong Zhou et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Sterile Inflammation in the Liver

(2012) Paul Kubes et al.   GASTROENTEROLOGY

High-mobility group box 1 protein blockade suppresses development of abdominal aortic aneurysm

(2012) Takashi Kohno et al.   Journal of Cardiology

Neutrophil extracellular traps: Is immunity the second function of chromatin?

(2012) Volker Brinkmann et al.   JOURNAL OF CELL BIOLOGY

Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease

(2012) J. Leffler et al.   JOURNAL OF IMMUNOLOGY

Peripheral RAGE (Receptor for Advanced Glycation Endproducts)-ligands in normal pregnancy and preeclampsia: novel markers of inflammatory response

(2012) Katsuhiko Naruse et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Deciphering the role of NETs and networks in SLE

(2012) Thomas Dörner   Nature Reviews Rheumatology

Human macrophage and dendritic cell-specific silencing of high-mobility group protein B1 ameliorates sepsis in a humanized mouse model

(2012) C. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Urine levels of HMGB1 in Systemic Lupus Erythematosus patients with and without renal manifestations

(2012) Deena A Abdulahad et al.   ARTHRITIS RESEARCH & THERAPY

Desempenho diagnóstico e associações clínicas dos anticorpos contra componentes da cromatina no lúpus eritematoso sistêmico juvenil

(2012) Silene Peres Keusseyan et al.   Revista Brasileira De Reumatologia

Anticorpos anti-C1q, anticromatina/nucleossomo e anti-dsDNA em pacientes com lúpus eritematoso sistêmico juvenil

(2012) Adriana Almeida de Jesus et al.   Revista Brasileira De Reumatologia

Autoantibodies to intracellular antigens: Generation and pathogenetic role

(2011) Vito Racanelli et al.   AUTOIMMUNITY REVIEWS

HMGB1 cytoplasmic translocation in patients with acute liver failure

(2011) Rong-Rong Zhou et al.   BMC GASTROENTEROLOGY

Hyperlipidemia stimulates the extracellular release of the nuclear high mobility group box 1 protein

(2011) Raluca Haraba et al.   CELL AND TISSUE RESEARCH

Geographical Differences in Autoantibodies and Anti-infectious Agents Antibodies Among Healthy Adults

(2011) Yinon Shapira et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Antinucleosome in systemic lupus erythematosus. A study in a Brazilian population

(2011) G. A. Sardeto et al.   CLINICAL RHEUMATOLOGY

Circulating levels of chromatin fragments are inversely correlated with anti-dsDNA antibody levels in human and murine systemic lupus erythematosus

(2011) Mariann H. Jørgensen et al.   IMMUNOLOGY LETTERS

Emergence of autoantibodies to HMGB1 is associated with survival in patients with septic shock

(2011) Stéphanie Barnay-Verdier et al.   INTENSIVE CARE MEDICINE

Fluvastatin reduces the high mobility group box 1 protein expression in hyperlipidemia

(2011) Raluca Haraba et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus

(2011) Anirudh J. Ullal et al.   JOURNAL OF AUTOIMMUNITY

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

High-mobility group box 1 represents a potential marker of disease activity and novel therapeutic target in systemic lupus erythematosus

(2011) V. Urbonaviciute et al.   JOURNAL OF INTERNAL MEDICINE

Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures

(2011) Jieun Choi et al.   Journal of Neuroinflammation

Postoperative Serum Concentrations of High Mobility Group Box Chromosomal Protein-1 Correlates to the Duration of SIRS and Pulmonary Dysfunction Following Gastrointestinal Surgery

(2011) Risa Takahata et al.   JOURNAL OF SURGICAL RESEARCH

The neutrophil in vascular inflammation

(2011) Mia Phillipson et al.   NATURE MEDICINE

Nonrenal and renal activity of systemic lupus erythematosus: a comparison of two anti-C1q and five anti-dsDNA assays and complement C3 and C4

(2011) Heikki Julkunen et al.   RHEUMATOLOGY INTERNATIONAL

Dissecting the Immune Cell Mayhem That Drives Lupus Pathogenesis

(2011) J. E. Craft   Science Translational Medicine

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Lupus Nephritis: Role of Antinucleosome Autoantibodies

(2011) Johan van der Vlag et al.   SEMINARS IN NEPHROLOGY

High mobility group box protein-1 (HMGB-1) as a new diagnostic marker in patients with acute appendicitis

(2011) Yavuz Albayrak et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus

(2010) C. C. van Bavel et al.   ANNALS OF THE RHEUMATIC DISEASES

Updating on the pathogenesis of systemic lupus erythematosus

(2010) R. Gualtierotti et al.   AUTOIMMUNITY REVIEWS

Impact of serum high-mobility group box 1 protein elevation on oxygenation impairment after thoracic aortic aneurysm repair

(2010) Takashi Kohno et al.   HEART AND VESSELS

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Comparison between multiplex assays for autoantibody detection in systemic lupus erythematosus

(2010) John G. Hanly et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Performance of a multiplex assay compared to enzyme and precipitation methods for anti-ENA testing in systemic lupus and systemic sclerosis

(2010) S. Albon et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Expression of High Mobility Group Box Chromosomal Protein 1 and Its Modulating Effects on Downstream Cytokines in Systemic Lupus Erythematosus

(2010) J. LI et al.   JOURNAL OF RHEUMATOLOGY

Diagnosing systemic lupus erythematosus: new-generation immunoassays for measurement of anti-dsDNA antibodies are an effective alternative to the Farr technique and the Crithidia luciliae immunofluorescence test

(2010) A. Antico et al.   LUPUS

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is HMGB1 a New Indirect Marker for Revealing Fibrosis in Chronic Hepatitis and a New Therapeutic Target in Treatment?

(2010) Ayse Albayrak et al.   VIRAL IMMUNOLOGY

BioPlex™ 2200 multiplexed system: Simultaneous detection of anti-dsDNA and anti-chromatin antibodies in patients with systemic lupus erythematosus

(2009) Nathalie Bardin et al.   AUTOIMMUNITY

Cisplatin prevents high mobility group box 1 release and is protective in a murine model of hepatic ischemia/reperfusion injury

(2009) Jon Cardinal et al.   HEPATOLOGY

Anti-nucleosome antibodies as a disease activity marker in patients with systemic lupus erythematosus

(2009) Suleiman SULEIMAN et al.   International Journal of Rheumatic Diseases

Nephritogenic Potential of Anti-DNA Antibodies against Necrotic Nucleosomes

(2009) E. S. Mortensen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Anti-nucleosome and anti-chromatin antibodies are present in active systemic lupus erythematosus but not in the cutaneous form of the disease

(2009) A Souza et al.   LUPUS

Lupus antibodies to the HMGB1 chromosomal protein: epitope mapping and association with disease activity

(2009) Ayako Hayashi et al.   Modern Rheumatology

Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies

(2009) Casandra C. van Bavel et al.   MOLECULAR IMMUNOLOGY

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

The Role of Extracellular DNA in Autoimmunity in SLE

(2009) K.-Y. Su et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Mechanisms of Toll-Like Receptor 4 (TLR4)-Mediated Inflammation After Cold Ischemia/Reperfusion in the Heart

(2009) David J. Kaczorowski et al.   TRANSPLANTATION

Lupus Nephritis

(2008) Elin S. Mortensen et al.   AMERICAN JOURNAL OF PATHOLOGY

The Role of High Mobility Group Box1 in Pulmonary Fibrosis

(2008) Naoki Hamada et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Predictive value of anti-dsDNA autoantibodies: Importance of the assay

(2008) Luis E. Munoz et al.   AUTOIMMUNITY REVIEWS

The antichromatin antibodies can be useful as a diagnostic tool and disease activity marker of systemic lupus erythematosus in Koreans

(2008) Hyoun-Ah Kim et al.   CLINICAL IMMUNOLOGY

The content of DNA and RNA in microparticles released by Jurkat and HL-60 cells undergoing in vitro apoptosis

(2008) Charles F. Reich et al.   EXPERIMENTAL CELL RESEARCH

Antinucleosome antibodies in primary antiphospholipid syndrome: A hint at systemic autoimmunity?

(2008) Laura Andreoli et al.   JOURNAL OF AUTOIMMUNITY

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The HMGB1 Receptor RAGE Mediates Ischemic Brain Damage

(2008) S. Muhammad et al.   JOURNAL OF NEUROSCIENCE

High mobility group box 1 (HMGB1) and macrophage migration inhibitory factor (MIF) in Kawasaki disease

(2008) T. Hoshina et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease

(2008) David S Pisetsky et al.   ARTHRITIS RESEARCH & THERAPY

The role of high-mobility group box 1 protein in the pathogenesis of autoimmune diseases

(2008) Reinhard E. Voll et al.   Current Rheumatology Reports