The Role of Microparticles in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus

Targeting the SYK–BTK axis for the treatment of immunological and hematological disorders

(2013) Seng-Lai Tan et al.   PHARMACOLOGY & THERAPEUTICS

Increased IgG on cell-derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation

(2012) Christoffer T. Nielsen et al.   ARTHRITIS AND RHEUMATISM

During apoptosis HMGB1 is translocated into apoptotic cell-derived membraneous vesicles

(2012) Martin Schiller et al.   AUTOIMMUNITY

The role of microparticles in the generation of immune complexes in murine lupus

(2012) Anirudh J. Ullal et al.   CLINICAL IMMUNOLOGY

The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes

(2012) Nathalie Cloutier et al.   EMBO Molecular Medicine

Bruton's Tyrosine Kinase mediates platelet receptor-induced generation of microparticles: A potential mechanism for amplification of inflammatory responses in rheumatoid arthritis synovial joints

(2012) Jonathan Hsu et al.   IMMUNOLOGY LETTERS

Hypoxia—a key regulator of angiogenesis and inflammation in rheumatoid arthritis

(2012) Sofia Konisti et al.   Nature Reviews Rheumatology

Microparticles as mediators and biomarkers of rheumatic disease

(2012) D. S. Pisetsky et al.   RHEUMATOLOGY

Distinct features of circulating microparticles and their relationship to clinical manifestations in systemic lupus erythematosus

(2011) Christoffer T. Nielsen et al.   ARTHRITIS AND RHEUMATISM

Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus

(2011) Anirudh J. Ullal et al.   JOURNAL OF AUTOIMMUNITY

Anti-Neutrophil Cytoplasmic Antibodies Stimulate Release of Neutrophil Microparticles

(2011) Y. Hong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

(2011) Angélique Bobrie et al.   TRAFFIC

The release of microparticles by Jurkat leukemia T cells treated with staurosporine and related kinase inhibitors to induce apoptosis

(2010) Anirudh J. Ullal et al.   APOPTOSIS

Cellular Mechanisms Underlying the Formation of Circulating Microparticles

(2010) Olivier Morel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Microparticles

(2010) Sebastian F. Mause et al.   CIRCULATION RESEARCH

Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity

(2010) Fatih M Uckun et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Microparticles as a source of extracellular DNA

(2010) David S. Pisetsky et al.   IMMUNOLOGIC RESEARCH

Microparticles stimulate angiogenesis by inducing ELR+ CXC-chemokines in synovial fibroblasts

(2010) Nicole Reich et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The release of microparticles by RAW 264.7 macrophage cells stimulated with TLR ligands

(2010) Julie Gauley et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Microparticles as autoadjuvants in the pathogenesis of SLE

(2010) David S. Pisetsky et al.   Nature Reviews Rheumatology

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production

(2010) E. Boilard et al.   SCIENCE

The majority of circulating platelet-derived microparticles fail to bind annexin V, lack phospholipid-dependent procoagulant activity and demonstrate greater expression of glycoprotein Ib

(2010) Thomas Exner et al.   THROMBOSIS AND HAEMOSTASIS

Circulating microparticles remain associated with complement activation despite intensive anti-inflammatory therapy in early rheumatoid arthritis

(2009) I. C. van Eijk et al.   ANNALS OF THE RHEUMATIC DISEASES

Recent insights into the genetic basis of systemic lupus erythematosus

(2009) K L Moser et al.   GENES AND IMMUNITY

Aggregation and Microparticle Production Through Toll-like Receptor 4 Activation in Platelets From Recently Menopausal Women

(2009) Kazunori Hashimoto et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

The role of microparticles in the pathogenesis of rheumatic diseases

(2009) Christian Beyer et al.   Nature Reviews Rheumatology

A multicolor flow cytometric assay for measurement of platelet-derived microparticles

(2009) Fariborz Mobarrez et al.   THROMBOSIS RESEARCH

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Microparticle-induced release of B-lymphocyte regulators by rheumatoid synoviocytes

(2009) Laurent Messer et al.   ARTHRITIS RESEARCH & THERAPY

Platelet P2Y 12 Receptor Influences the Vessel Wall Response to Arterial Injury and Thrombosis

(2008) D.J.W. Evans et al.   CIRCULATION

The content of DNA and RNA in microparticles released by Jurkat and HL-60 cells undergoing in vitro apoptosis

(2008) Charles F. Reich et al.   EXPERIMENTAL CELL RESEARCH

The active metabolite of prasugrel effectively blocks the platelet P2Y12receptor and inhibits procoagulant and pro-inflammatory platelet responses

(2008) Heather M. Judge et al.   PLATELETS

Flow cytometric measurement of microparticles: Pitfalls and protocol modifications

(2008) Mona D. Shah et al.   PLATELETS