IL-6 as a Druggable Target in Psoriasis: Focus on Pustular Variants
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Title
IL-6 as a Druggable Target in Psoriasis: Focus on Pustular Variants
Authors
Keywords
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Journal
Journal of Immunology Research
Volume 2014, Issue -, Pages 1-10
Publisher
Hindawi Limited
Online
2014-07-14
DOI
10.1155/2014/964069
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Note: Only part of the references are listed.- Targeting the Interleukin-12/23 Cytokine Family in the Treatment of Psoriatic Disease
- (2015) Neil H. Shear et al. JOURNAL OF CUTANEOUS MEDICINE AND SURGERY
- IL-8 as Antibody Therapeutic Target in Inflammatory Diseases: Reduction of Clinical Activity in Palmoplantar Pustulosis
- (2014) L. Skov et al. JOURNAL OF IMMUNOLOGY
- Clinical and epidemiological comparison of patients affected by palmoplantar plaque psoriasis and palmoplantar pustulosis: a case series study
- (2013) A.M.G. Brunasso et al. BRITISH JOURNAL OF DERMATOLOGY
- Successful therapy with anakinra in a patient with generalized pustular psoriasis carryingIL36RNmutations
- (2013) U. Hüffmeier et al. BRITISH JOURNAL OF DERMATOLOGY
- Autoinflammatory Pustular Neutrophilic Diseases
- (2013) Haley B. Naik et al. DERMATOLOGIC CLINICS
- IL-17 plays a central role in initiating experimentalCandida albicansinfection in mouse corneas
- (2013) Hongbo Zhang et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Jakpot! New small molecules in autoimmune and inflammatory diseases
- (2013) Kamran Ghoreschi et al. EXPERIMENTAL DERMATOLOGY
- Update on biologicals for treatment of juvenile idiopathic arthritis
- (2013) Gerd Horneff EXPERT OPINION ON BIOLOGICAL THERAPY
- IL-17 targeted therapies for psoriasis
- (2013) Andrea Chiricozzi et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Genetic variations in IL6 and IL12B decreasing the risk for psoriasis
- (2013) Andreea Nicoleta Boca et al. IMMUNOLOGY LETTERS
- Psoriasis onset with tocilizumab
- (2013) Anne Grasland et al. JOINT BONE SPINE
- IL-1R1 Signaling Facilitates Munro’s Microabscess Formation in Psoriasiform Imiquimod-Induced Skin Inflammation
- (2013) Mireia Uribe-Herranz et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL36RN Mutations in Generalized Pustular Psoriasis: Just the Tip of the Iceberg?
- (2013) Francesca Capon JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Rare Pathogenic Variants in IL36RN Underlie a Spectrum of Psoriasis-Associated Pustular Phenotypes
- (2013) Niovi Setta-Kaffetzi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- NF-κB and STAT3 Inhibition as a Therapeutic Strategy in Psoriasis: In Vitro and In Vivo Effects of BTH
- (2013) Rosa M. Andrés et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Prevalent and Rare Mutations in IL-36RN Gene in Chinese Patients with Generalized Pustular Psoriasis and Psoriasis Vulgaris
- (2013) Ming Li et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Majority of Generalized Pustular Psoriasis without Psoriasis Vulgaris Is Caused by Deficiency of Interleukin-36 Receptor Antagonist
- (2013) Kazumitsu Sugiura et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Mutations in IL36RN in Patients with Generalized Pustular Psoriasis
- (2013) Andreas Körber et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Loss of IL36RN Function Does Not Confer Susceptibility to Psoriasis Vulgaris
- (2013) Dorottya M. Berki et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients
- (2013) Paola Di Meglio et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-6 Regulates Neutrophil Microabscess Formation in IL-17A-Driven Psoriasiform Lesions
- (2013) Andrew L. Croxford et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Acute treatment of generalized pustular psoriasis of von Zumbusch with single-dose infliximab
- (2013) Noah Smith et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Therapeutic depletion of myeloid lineage leukocytes in patients with generalized pustular psoriasis indicates a major role for neutrophils in the immunopathogenesis of psoriasis
- (2013) Shigaku Ikeda et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Effects of adalimumab therapy in adult subjects with moderate-to-severe psoriasis on Th17 pathway
- (2013) A. Balato et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Increased expression of IL-17A and limited involvement of IL-23 in patients with palmo-plantar (PP) pustular psoriasis or PP pustulosis; results from a randomised controlled trial
- (2013) R. Bissonnette et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- First Clinical Description of an Infant With Interleukin-36-Receptor Antagonist Deficiency Successfully Treated With Anakinra
- (2013) L. Rossi-Semerano et al. PEDIATRICS
- The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses
- (2013) Michelle A. Lowes et al. TRENDS IN IMMUNOLOGY
- Efficacy and Safety of Tumor Necrosis Factor Inhibitors in Acute Generalized Pustular Psoriasis
- (2012) Manuelle Viguier ARCHIVES OF DERMATOLOGY
- Efficacy and safety of tofacitinib, an oral Janus kinase inhibitor, in the treatment of psoriasis: a Phase 2b randomized placebo-controlled dose-ranging study
- (2012) K.A. Papp et al. BRITISH JOURNAL OF DERMATOLOGY
- Th17 Cells in Immunity to Candida albicans
- (2012) Nydiaris Hernández-Santos et al. Cell Host & Microbe
- Experimentally induced psoriatic lesion associates with interleukin (IL)-6 in mast cells and appearance of dermal cells expressing IL-33 and IL-6 receptor
- (2012) M.-M. Suttle et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis
- (2012) Anne Puel et al. Current Opinion in Allergy and Clinical Immunology
- IL-36 in psoriasis
- (2012) JE Towne et al. CURRENT OPINION IN PHARMACOLOGY
- Inhibition of the IL-6 signaling pathway: A strategy to combat chronic inflammatory diseases and cancer
- (2012) Parvin Ataie-Kachoie et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Immunity to infection in IL-17-deficient mice and humans
- (2012) Sophie Cypowyj et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- IL-6, IL-17 and STAT3: a holy trinity in auto-immunity?
- (2012) Annalisa Camporeale Frontiers in Bioscience-Landmark
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- (2012) Stefan Rose-John International Journal of Biological Sciences
- Successful effect of tocilizumab in anti-TNF-α-induced palmoplantar pustulosis in rheumatoid arthritis
- (2012) Javier Rueda-Gotor et al. JOINT BONE SPINE
- Psoriasiform dermatitis is driven by IL-36–mediated DC-keratinocyte crosstalk
- (2012) Luigi Tortola et al. JOURNAL OF CLINICAL INVESTIGATION
- Cutting Edge: IL-17-Secreting Innate Lymphoid Cells Are Essential for Host Defense against Fungal Infection
- (2012) A. Gladiator et al. JOURNAL OF IMMUNOLOGY
- An Alternative Pathway of Imiquimod-Induced Psoriasis-Like Skin Inflammation in the Absence of Interleukin-17 Receptor A Signaling
- (2012) Khalifa El Malki et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Emerging Role of IL-17 in the Pathogenesis of Psoriasis: Preclinical and Clinical Findings
- (2012) David A. Martin et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Psoriasis Onset with Tocilizumab Treatment for Rheumatoid Arthritis
- (2012) D. WENDLING et al. JOURNAL OF RHEUMATOLOGY
- Tumor Necrosis Factor-associated Palmoplantar Pustular Psoriasis Treated with Interleukin 6 Blocker
- (2012) S. YOUNIS et al. JOURNAL OF RHEUMATOLOGY
- Treatment of pustular psoriasis: From the Medical Board of the National Psoriasis Foundation
- (2012) Amanda Robinson et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis
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- (2012) Mercedes Rincon TRENDS IN IMMUNOLOGY
- Clinical and Laboratory Features in Acute Generalized Pustular Psoriasis
- (2011) João Borges-Costa et al. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
- Expression of interleukin (IL)-1 family members upon stimulation with IL-17 differs in keratinocytes derived from patients with psoriasis and healthy donors
- (2011) P. Muhr et al. BRITISH JOURNAL OF DERMATOLOGY
- The value of blocking IL-6 outside of rheumatoid arthritis: current perspective
- (2011) Miho Murakami et al. CURRENT OPINION IN RHEUMATOLOGY
- IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer
- (2011) Markus F. Neurath et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Recent advances in IL-22 biology
- (2011) L. A. Zenewicz et al. INTERNATIONAL IMMUNOLOGY
- Human slan (6-sulfo LacNAc) dendritic cells are inflammatory dermal dendritic cells in psoriasis and drive strong Th17/Th1 T-cell responses
- (2011) Anja Hänsel et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
- (2011) Simon A. Jones et al. JOURNAL OF CLINICAL INVESTIGATION
- Flare of pustular psoriasis after initiating ustekinumab therapy
- (2011) Kurt S. Wenk et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- IL-21 Promotes Skin Recruitment of CD4+ Cells and Drives IFN- -Dependent Epidermal Hyperplasia
- (2011) M. Sarra et al. JOURNAL OF IMMUNOLOGY
- Distinct Roles of IL-23 and IL-17 in the Development of Psoriasis-Like Lesions in a Mouse Model
- (2011) Kimiko Nakajima et al. JOURNAL OF IMMUNOLOGY
- Epidermal CCR6 + γδ T Cells Are Major Producers of IL-22 and IL-17 in a Murine Model of Psoriasiform Dermatitis
- (2011) Tomotaka Mabuchi et al. JOURNAL OF IMMUNOLOGY
- IL-22 Is Required for Imiquimod-Induced Psoriasiform Skin Inflammation in Mice
- (2011) A. B. Van Belle et al. JOURNAL OF IMMUNOLOGY
- IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression
- (2011) A. Johnston et al. JOURNAL OF IMMUNOLOGY
- Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis
- (2011) A. M. Lin et al. JOURNAL OF IMMUNOLOGY
- IL-23-Mediated Epidermal Hyperplasia Is Dependent on IL-6
- (2011) Josefine Lindroos et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-17A Upregulates Keratin 17 Expression in Keratinocytes through STAT1- and STAT3-Dependent Mechanisms
- (2011) Xiaowei Shi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Inter-Regulation of Th17 Cytokines and the IL-36 Cytokines In Vitro and In Vivo: Implications in Psoriasis Pathogenesis
- (2011) Yijun Carrier et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis
- (2011) Trilokraj Tejasvi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis
- (2011) Slaheddine Marrakchi et al. NEW ENGLAND JOURNAL OF MEDICINE
- −174G/C IL-6 gene promoter polymorphism predicts therapeutic response to TNF-α blockers
- (2011) Laura Di Renzo et al. Pharmacogenetics and Genomics
- Involvement of IL-17F via the induction of IL-6 in psoriasis
- (2010) Sawa Fujishima et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Signal transduction pathways and transcriptional regulation in Th17 cell differentiation
- (2010) Kiyoshi Hirahara et al. CYTOKINE & GROWTH FACTOR REVIEWS
- The histopathological spectrum of acute generalized exanthematous pustulosis (AGEP) and its differentiation from generalized pustular psoriasis
- (2010) Sylvia H. Kardaun et al. JOURNAL OF CUTANEOUS PATHOLOGY
- Serum IL-22 correlates with psoriatic severity and serum IL-6 correlates with susceptibility to phototherapy
- (2010) Yuan-Hsin Lo et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Onset of palmoplantar pustular psoriasis while on adalimumab for psoriatic arthritis: A ‘class effect’ of TNF-α antagonists or simply an anti-psoriatic treatment adverse reaction?
- (2010) Efstathios Rallis et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- IL-23-Mediated Psoriasis-Like Epidermal Hyperplasia Is Dependent on IL-17A
- (2010) H. L. Rizzo et al. JOURNAL OF IMMUNOLOGY
- IL-1RL2 and Its Ligands Contribute to the Cytokine Network in Psoriasis
- (2010) H. Blumberg et al. JOURNAL OF IMMUNOLOGY
- Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor
- (2010) Ken Miyoshi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis
- (2010) Andrea Chiricozzi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis
- (2009) L. van der Fits et al. JOURNAL OF IMMUNOLOGY
- IL-6 Signaling in Psoriasis Prevents Immune Suppression by Regulatory T Cells
- (2009) W. A. Goodman et al. JOURNAL OF IMMUNOLOGY
- The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis
- (2009) Antonella Di Cesare et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Circulating Th17, Th22, and Th1 Cells Are Increased in Psoriasis
- (2009) Shinji Kagami et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-6 and IL-10 Promoter Gene Polymorphisms in Psoriasis Vulgaris
- (2008) W Baran et al. ACTA DERMATO-VENEREOLOGICA
- Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
- (2008) K.E. Nograles et al. BRITISH JOURNAL OF DERMATOLOGY
- Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
- (2008) Hideki Ogura et al. IMMUNITY
- Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells
- (2008) Michelle A. Lowes et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
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