Identification of Novel Candidate Markers of Type 2 Diabetes and Obesity in Russia by Exome Sequencing with a Limited Sample Size

Genomic insights into the causes of type 2 diabetes

(2018) Claudia Langenberg et al.   LANCET

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

(2018) Anubha Mahajan et al.   NATURE GENETICS

Paediatric genomics: diagnosing rare disease in children

(2018) Caroline F. Wright et al.   NATURE REVIEWS GENETICS

Catching hidden variation: systematic correction of reference minor allele annotation in clinical variant calling

(2017) Yury A Barbitoff et al.   GENETICS IN MEDICINE

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

(2017) Valérie Turcot et al.   NATURE GENETICS

Genome-wide meta-analysis in Japanese populations identifies novel variants at the TMC6–TMC8 and SIX3–SIX2 loci associated with HbA1c

(2017) Tsuyoshi Hachiya et al.   Scientific Reports

dbNSFP v3.0: A One-Stop Database of Functional Predictions and Annotations for Human Nonsynonymous and Splice-Site SNVs

(2016) Xiaoming Liu et al.   HUMAN MUTATION

The genetic architecture of type 2 diabetes

(2016) Christian Fuchsberger et al.   NATURE

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

(2016) Georg B Ehret et al.   NATURE GENETICS

Vav3 is linked to poor prognosis of pancreatic cancers and promotes the motility and invasiveness of pancreatic cancer cells

(2016) Makiko Tsuboi et al.   PANCREATOLOGY

Comprehensive Map of Molecules Implicated in Obesity

(2016) Jaisri Jagannadham et al.   PLoS One

PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels

(2015) Yongwook Choi et al.   BIOINFORMATICS

Targeted next-generation sequencing (NGS) of nine candidate genes with custom AmpliSeq in patients and a cardiomyopathy risk group

(2015) Andrey S. Glotov et al.   CLINICA CHIMICA ACTA

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Genetic markers of type 2 diabetes: Progress in genome-wide association studies and clinical application for risk prediction

(2015) Xueyin Wang et al.   Journal of Diabetes

Whole-Exome Sequencing of 2,000 Danish Individuals and the Role of Rare Coding Variants in Type 2 Diabetes

(2013) Kirk E. Lohmueller et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Whole exome sequencing identifies variation inCYB5AandRNF10associated with adiposity and type 2 diabetes

(2013) Ke Huang et al.   Obesity

Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci

(2013) Ching-Ti Liu et al.   PLoS Genetics

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

(2012) A. Albrechtsen et al.   DIABETOLOGIA

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

(2012) Robert A Scott et al.   NATURE GENETICS

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

(2010) Albena T. Dinkova-Kostova et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Prevention of Overweight and Obesity: How Effective is the Current Public Health Approach

(2010) Ruth S.M. Chan et al.   International Journal of Environmental Research and Public Health

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

ADAMTS13 and von Willebrand factor concentrations in patients with diabetes mellitus

(2009) Mika Skeppholm et al.   BLOOD COAGULATION & FIBRINOLYSIS

RREB-1 Is a Transcriptional Repressor of HLA-G

(2009) S. Flajollet et al.   JOURNAL OF IMMUNOLOGY