Regulation of Pancreatic Beta Cell Stimulus-Secretion Coupling by microRNAs

Role of non-coding RNAs in pancreatic beta-cell development and physiology

(2014) L. Eliasson et al.   Acta Physiologica

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

(2014) Anna Edlund et al.   BMC Medicine

Epigenetic Regulation of the DLK1-MEG3 MicroRNA Cluster in Human Type 2 Diabetic Islets

(2014) Vasumathi Kameswaran et al.   Cell Metabolism

Thioredoxin-interacting Protein Promotes Islet Amyloid Polypeptide Expression through miR-124a and FoxA2

(2014) Gu Jing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-7a regulates pancreatic β cell function

(2014) Mathieu Latreille et al.   JOURNAL OF CLINICAL INVESTIGATION

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

(2014) J. Fadista et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Could microRNAs contribute to the maintenance of β cell identity?

(2014) Haggai Kaspi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Contact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site

(2014) Nikhil R. Gandasi et al.   Nature Communications

Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion

(2014) Tasnim Dayeh et al.   PLoS Genetics

Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans

(2014) Jonathan L. S. Esguerra et al.   Frontiers in Genetics

Regulation of ABCA1 Protein Expression and Function in Hepatic and Pancreatic Islet Cells by miR-145

(2013) Martin H. Kang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tumor-suppressivemicroRNA-143/145cluster targets hexokinase-2 in renal cell carcinoma

(2013) Hirofumi Yoshino et al.   CANCER SCIENCE

Syntaxin-1a is a Direct Target of miR-29a in Insulin-producing β-Cells

(2013) A. Bagge et al.   HORMONE AND METABOLIC RESEARCH

miR-153 Regulates SNAP-25, Synaptic Transmission, and Neuronal Development

(2013) Chunyao Wei et al.   PLoS One

The miRNA Profile of Human Pancreatic Islets and Beta-Cells and Relationship to Type 2 Diabetes Pathogenesis

(2013) Martijn van de Bunt et al.   PLoS One

MicroRNA Expression in Alpha and Beta Cells of Human Pancreatic Islets

(2013) Dagmar Klein et al.   PLoS One

MicroRNA-301a Mediated Regulation of Kv4.2 in Diabetes: Identification of Key Modulators

(2013) Siva K. Panguluri et al.   PLoS One

Regulation of Insulin Secretion in Human Pancreatic Islets

(2012) Patrik Rorsman et al.   Annual Review of Physiology

MicroRNA-29a is up-regulated in beta-cells by glucose and decreases glucose-stimulated insulin secretion

(2012) Annika Bagge et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diabetes Mellitus and the β Cell: The Last Ten Years

(2012) Frances M. Ashcroft et al.   CELL

Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic  -Cells Leads to Relative Hyperinsulinism During Exercise

(2012) T. J. Pullen et al.   DIABETES

Changes in MicroRNA Expression Contribute to Pancreatic  -Cell Dysfunction in Prediabetic NOD Mice

(2012) E. Roggli et al.   DIABETES

When less is more: the forbidden fruits of gene repression in the adult β-cell

(2012) T. J. Pullen et al.   DIABETES OBESITY & METABOLISM

Emerging roles of non-coding RNAs in pancreatic β-cell function and dysfunction

(2012) C. Guay et al.   DIABETES OBESITY & METABOLISM

A novel miR-155/miR-143 cascade controls glycolysis by regulatinghexokinase 2in breast cancer cells

(2012) Shuai Jiang et al.   EMBO JOURNAL

MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulatingGLUT3expression

(2012) Xiang Fei et al.   FEBS LETTERS

MicroRNA-30d Induces Insulin Transcription Factor MafA and Insulin Production by Targeting Mitogen-activated Protein 4 Kinase 4 (MAP4K4) in Pancreatic β-Cells

(2012) Xiaomin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs Are Essential for Stretch-induced Vascular Smooth Muscle Contractile Differentiation via MicroRNA (miR)-145-dependent Expression of L-type Calcium Channels

(2012) Karolina M. Turczyńska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes

(2012) Sofia A. Andersson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC

(2012) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular, Cellular and Structural Mechanisms of Cocaine Addiction: A Key Role for MicroRNAs

(2012) Sietse Jonkman et al.   NEUROPSYCHOPHARMACOLOGY

Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells

(2011) R. Hage Hassan et al.   DIABETOLOGIA

miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors

(2011) Tal Melkman-Zehavi et al.   EMBO JOURNAL

Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain

(2011) Alexandre Favereaux et al.   EMBO JOURNAL

Nkx2.2 repressor complex regulates islet  -cell specification and prevents  -to- -cell reprogramming

(2011) J. B. Papizan et al.   GENES & DEVELOPMENT

miR-29a and miR-29b Contribute to Pancreatic  -Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)

(2011) T. J. Pullen et al.   MOLECULAR AND CELLULAR BIOLOGY

GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: Implications for understanding genetic association signals at this locus

(2011) Laura J. McCulloch et al.   MOLECULAR GENETICS AND METABOLISM

Differential Glucose-Regulation of MicroRNAs in Pancreatic Islets of Non-Obese Type 2 Diabetes Model Goto-Kakizaki Rat

(2011) Jonathan Lou S. Esguerra et al.   PLoS One

Expression and Localization of microRNAs in Perinatal Rat Pancreas: Role of miR-21 in Regulation of Cholesterol Metabolism

(2011) Louise Larsen et al.   PLoS One

Beta-Cell Specific Deletion of Dicer1 Leads to Defective Insulin Secretion and Diabetes Mellitus

(2011) Martins Kalis et al.   PLoS One

Diabetes mellitus, a microRNA-related disease?

(2011) Claudiane Guay et al.   Translational Research

Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects

(2010) Caroline Bolmeson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterizing Light-Regulated Retinal MicroRNAs Reveals Rapid Turnover as a Common Property of Neuronal MicroRNAs

(2010) Jacek Krol et al.   CELL

MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial Fibrillation

(2010) Yanjie Lu et al.   CIRCULATION

MicroRNA-15a positively regulates insulin synthesis by inhibiting uncoupling protein-2 expression

(2010) Liang-Liang Sun et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation

(2010) L. Thorrez et al.   GENOME RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Suppression of Sulfonylurea- and Glucose-Induced Insulin Secretion In Vitro and In Vivo in Mice Lacking the Chloride Transport Protein ClC-3

(2009) Dai-Qing Li et al.   Cell Metabolism

Genetic basis of β-cell dysfunction in man

(2009) L. Groop et al.   DIABETES OBESITY & METABOLISM

Roles of cAMP signalling in insulin granule exocytosis

(2009) S. Seino et al.   DIABETES OBESITY & METABOLISM

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

The Promoter of the pri-miR-375 Gene Directs Expression Selectively to the Endocrine Pancreas

(2009) Tali Avnit-Sagi et al.   PLoS One

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptotagmins bind calcium to release insulin

(2008) Benoit R. Gauthier et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Why expression of some genes is disallowed in β-cells

(2008) Roel Quintens et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs

(2008) Pascal Lovis et al.   BIOLOGICAL CHEMISTRY

miR-375 Targets 3'-Phosphoinositide-Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic  -Cells

(2008) A. El Ouaamari et al.   DIABETES

Alterations in MicroRNA Expression Contribute to Fatty Acid-Induced Pancreatic  -Cell Dysfunction

(2008) P. Lovis et al.   DIABETES

Chromatin structure analyses identify miRNA promoters

(2008) F. Ozsolak et al.   GENES & DEVELOPMENT

Novel aspects of the molecular mechanisms controlling insulin secretion

(2008) Lena Eliasson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic β cell

(2008) Andreia S. Bernardo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Munc 18-1 and Granuphilin Collaborate During Insulin Granule Exocytosis

(2008) Alejandra Tomas et al.   TRAFFIC